Center for Regenerative Medicine (CRM) Support for New Faculty Member
再生医学中心 (CRM) 对新教员的支持
基本信息
- 批准号:7936151
- 负责人:
- 金额:$ 76.12万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2009
- 资助国家:美国
- 起止时间:2009-09-30 至 2011-08-31
- 项目状态:已结题
- 来源:
- 关键词:AdvertisingAppointmentAreaArtsAttentionAwardBioinformaticsBiologyBiomedical EngineeringBloodBostonBusinessesCardiacCellular biologyClinicalClinical TrialsCommitCommunitiesComplementComputational BiologyCore FacilityCritical CareDevelopmentDevelopmental BiologyDockingEducational process of instructingFacultyFosteringFoundationsFundingFutureGeneral HospitalsGeneticGrantHeartHospital DepartmentsHousingHumanIndividualInstitutesInternal MedicineInternationalKidneyLaboratoriesLeadershipLiverLungLung diseasesMassachusettsMedicineMentorsMusculoskeletal SystemNational Heart, Lung, and Blood InstituteNatural regenerationNervous system structureNew YorkOperative Surgical ProceduresPhysiciansPolymersPositioning AttributePulmonologyRecruitment ActivityRegenerative MedicineResearchResourcesScientistSecureStem cellsTherapeutic UsesTrainingTranslatingUniversitiesWorkbasebody systemcell preparationhuman diseaseinterestmedical schoolsmeetingsmembermultidisciplinaryneurosurgerypediatric departmentprofessorprogramsregenerativestem cell biologysuccess
项目摘要
DESCRIPTION (provided by applicant): This application is seeking support for a new Assistant Professor in the Center for Regenerative Medicine (CRM), at the Massachusetts General Hospital (MGH), Harvard Medical School. This individual will be located in recently completed laboratory and office space for CRM, on the MGH main campus, as part of a 10 faculty physically adjoined unit within the Simches Building housing five interdisciplinary centers. The CRM space is open lab format to encourage interaction and includes GMP level facilities for clinical grade cell preparations, a polymer handling suite for bioengineered matrix construction and a computational biology suite housing a cadre of bioinformatics experts. The CRM is a multidisciplinary organization established in 2003 incorporating individuals from the Departments of Medicine, Surgery, Neurosurgery, Cell Biology, Genetics and Stem Cell and Regenerative Biology. After review of over 70 candidates, a physician-scientist with a record of excellent research in lung developmental and regenerative biology as well as clinical expertise in lung disease was selected. This candidate, Dr. Jayaraj Rajagopal, is focused on the application of lung stem cells and regeneration to human lung disease.
Aims: 1.) To recruit a physician-scientist focusing on stem cell based approaches to human disease
2.) To establish a laboratory with state-of-the-art facilities to enhance our understanding and potential application of lung developmental biology to lung disease.3.) To foster the success of a future thought leader in regenerative medicine for lung disease.
In contrast to recent progress in blood and cardiac stem cell biology, work in the lung remains underdeveloped. We wish to recruit a new faculty candidate to the Center for Regenerative Medicine at the Massachusetts General Hospital. We believe our candidate's interest in the therapeutic uses of lung stem cells and developmental biology will lay a foundation for regenerative medicine in the lung.
描述(由申请人提供):本申请寻求哈佛医学院马萨诸塞州总医院(MGH)再生医学中心(CRM)新助理教授的支持。这个人将位于最近完成的实验室和CRM办公空间,在MGH主校区,作为Simches大楼内的10个教师物理相邻单元的一部分,其中包括五个跨学科中心。CRM空间是开放的实验室形式,以鼓励互动,包括用于临床级细胞制备的GMP级设施,用于生物工程基质构建的聚合物处理套件和容纳生物信息学专家骨干的计算生物学套件。CRM是一个多学科组织,成立于2003年,由医学、外科、神经外科、细胞生物学、遗传学、干细胞和再生生物学系的个人组成。在对70多名候选人进行审查后,选出了一名在肺部发育和再生生物学以及肺部疾病临床专业知识方面具有出色研究记录的医生兼科学家。Jayaraj Rajagopal博士专注于肺干细胞和再生在人类肺部疾病中的应用。
目的:1.)招募一名专注于以干细胞为基础的人类疾病治疗方法的医生科学家
2.)的情况。建立一个拥有最先进设备的实验室,以提高我们对肺部发育生物学的理解和肺部疾病的潜在应用。促进未来肺部疾病再生医学思想领袖的成功。
与血液和心脏干细胞生物学的最新进展相反,肺部的工作仍然不发达。我们希望招聘一名新的教师候选人到马萨诸塞州总医院的再生医学中心。我们相信我们的候选人对肺干细胞和发育生物学的治疗用途的兴趣将为肺再生医学奠定基础。
项目成果
期刊论文数量(1)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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David T Scadden其他文献
The hematopoietic stem cell in its place
造血干细胞在它的位置上
- DOI:
10.1038/ni1331 - 发表时间:
2006-03-20 - 期刊:
- 影响因子:27.600
- 作者:
Gregor B Adams;David T Scadden - 通讯作者:
David T Scadden
Osteoclasts eat stem cells out of house and home
破骨细胞把干细胞赶尽杀绝。
- DOI:
10.1038/nm0606-610 - 发表时间:
2006-06-01 - 期刊:
- 影响因子:50.000
- 作者:
Louise E Purton;David T Scadden - 通讯作者:
David T Scadden
Cancer stem cells refined
癌症干细胞的提纯
- DOI:
10.1038/ni0704-701 - 发表时间:
2004-07-01 - 期刊:
- 影响因子:27.600
- 作者:
David T Scadden - 通讯作者:
David T Scadden
David T Scadden的其他文献
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{{ truncateString('David T Scadden', 18)}}的其他基金
Functional consequences of stem and progenitor cell heterogeneity
干细胞和祖细胞异质性的功能后果
- 批准号:
10413502 - 财政年份:2020
- 资助金额:
$ 76.12万 - 项目类别:
Enhancing regeneration of stem cell-derived HIV-specific immune effectors
增强干细胞衍生的 HIV 特异性免疫效应器的再生
- 批准号:
10163909 - 财政年份:2020
- 资助金额:
$ 76.12万 - 项目类别:
Enhancing regeneration of stem cell-derived HIV-specific immune effectors
增强干细胞衍生的 HIV 特异性免疫效应器的再生
- 批准号:
10409803 - 财政年份:2020
- 资助金额:
$ 76.12万 - 项目类别:
Functional consequences of stem and progenitor cell heterogeneity
干细胞和祖细胞异质性的功能后果
- 批准号:
10188996 - 财政年份:2020
- 资助金额:
$ 76.12万 - 项目类别:
Clonal tracking and molecular characterization of hematopoiesis under stress
应激条件下造血的克隆追踪和分子特征
- 批准号:
10413504 - 财政年份:2020
- 资助金额:
$ 76.12万 - 项目类别:
Enhancing regeneration of stem cell-derived HIV-specific immune effectors
增强干细胞衍生的 HIV 特异性免疫效应器的再生
- 批准号:
10601073 - 财政年份:2020
- 资助金额:
$ 76.12万 - 项目类别:
Project 1: Implications of blood cell heterogeneity for CV disease
项目 1:血细胞异质性对心血管疾病的影响
- 批准号:
10238040 - 财政年份:2019
- 资助金额:
$ 76.12万 - 项目类别:
Project 1: Implications of blood cell heterogeneity for CV disease
项目 1:血细胞异质性对心血管疾病的影响
- 批准号:
10469350 - 财政年份:2019
- 资助金额:
$ 76.12万 - 项目类别:
Project 1: Implications of blood cell heterogeneity for CV disease
项目 1:血细胞异质性对心血管疾病的影响
- 批准号:
10670732 - 财政年份:2019
- 资助金额:
$ 76.12万 - 项目类别:
Functional consequences of stem and progenitor cell heterogeneity
干细胞和祖细胞异质性的功能后果
- 批准号:
10641537 - 财政年份:2017
- 资助金额:
$ 76.12万 - 项目类别:
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