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中文摘要
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描述(由申请人提供):在当地医生办公室经常发现的广告,描绘了一个生活在寒冷世界中的小孩子,文字是“这个孩子有毒品问题”,记录了当今抗击疾病的非传统方法的必要性。事实上,戈登研究会议“医学中的金属:药物无机化学”就是这一事业的先锋。在肿瘤领域,顺铂和其他铂类药物已经证明了基于金属的药物的成功,其他领域仍有望等待类似的发现。然而,随着许多新方法的出现,过去的成功推动了搜索的继续,例如保罗·埃利希的抗梅毒药物阿尔芬胺(Salvarsan)。重要的是,研究人员和临床医生需要一个共同的论坛,在那里可以分享信息和策略。为此,必须创造肥沃的环境,使发现得以诞生。药物中的金属戈登研究会议将于2010年6月27日至7月2日在NH的普罗科特学院举行。本次会议将有来自不同背景和不同国籍的不同发言者的广泛发言。此外,这一组合将包括高级调查人员,以及初级调查人员和学生主持人。在这次会议上,将第一次从提交的摘要中挑选相当一部分青年科学家的发言,并在实验的基础上,为学生和年轻的和初学的科学家提供一个论坛,学习和发展关键技能,以开发新的疾病治疗方法。我们认为,增加这一新类型的陈述对我们的领域很重要,可以帮助促进伙伴关系和合作以及未来药物和治疗的发展。这种方法将允许一种形式来更新该地区的那些在临床上取得成功的情况,以及实验室在与疾病作斗争中的情况。在Metals in Medicine Gordon大会上,我们有机会将一群跨学科的科学家和医生聚集在一起,分享和学习无机化学、临床前开发中的生物化学、生物学和医学,以及在实验或医院类型的环境中治疗患者。在这次会议上,我们将讨论以下七个与健康相关的领域:肿瘤学、诊断/成像、核医学、传染病和神经退行性疾病、新陈代谢疾病、心血管疾病和老龄化。 与公共健康相关:戈登医学研究会议是一个多学科会议,化学家、生物化学家、生物学家、药剂师和临床医生齐聚一堂,学习基础科学和临床工作的最新技术。医学中的金属是一个快速发展的领域,记录了几种关键药物,如肿瘤学中的顺铂、核磁共振造影剂、心脏溶解放射性药物显像剂和纳米科学应用。这些抗击疾病的新的和非传统的方法需要多学科的联系,以验证研究人员在实验室和临床环境中开发所需的结果。会议将介绍以下七个与健康相关的领域的当前临床实践和发现水平的研究:肿瘤学、诊断/成像、核医学、传染病和神经退行性疾病、新陈代谢疾病、心血管疾病和老龄化。
英文摘要
DESCRIPTION (provided by applicant): Advertisements often found in the local physician's office, depicting a small child in a cold world with the text "this child has a drug problem" is documenting how much need there is for unconventional approaches to fight disease today. Indeed, the Gordon Research conference "Metals in Medicine: Medicinal Inorganic Chemistry" is spearheading just this cause. Solidly rooted in the area of oncology where cisplatin and other platinum drugs have documented the success of metal-based drugs, other areas are still hopefully waiting for similar discoveries. However, with many new approaches the search continues fueled by the past successes, such as Paul Ehrlich's anti-syphilitic agent arsphenamine (Salvarsan). Importantly, the researchers and clinicians need a common forum where information and strategies can be shared. To this end the fertile environment upon which discoveries can be born must be created. The Metals in Medicine Gordon Research Conference will be held at Proctor Academy, NH, June 27-July 2nd, 2010. This meeting will feature a broad range of presentations from a diverse group of speakers from different backgrounds and of different Nationalities. In addition, the mix will include senior level investigators, as well as beginning investigators and student presenters. For the first time in this conference a significant fraction of young scientist presentations will be selected from the submitted abstracts and on an experimental basis thus provide a forum for the students and young and beginning scientists to learn and develop key skills to develop new treatments of disease. We believe that the addition of this new type of presentation is important to our area and can help foster partnerships and collaborations and the development of the drug and treatments of tomorrow. Such an approach will allow a format to update those in the area what is successful in the clinic, as well as the laboratory in the battle of diseases. At the Metals in Medicine Gordon Conference we have the opportunity to bring together a group of interdisciplinary scientists and physicians to share and learn from inorganic chemistry, to biochemistry, biology and medicine in preclinical development and to treatment of patients in an experimental or hospital-type setting. At this meeting we will cover the following seven health-related areas: Oncology, Diagnostics/Imaging, Nuclear Medicine, Infectious and Neurodegenerative Diseases, Metabolic Disorders, Cardiovascular Malady, and Aging. PUBLIC HEALTH RELEVANCE: The Gordon Research Conference Metals in Medicine is a multidisciplinary meeting, in which chemists, biochemists, biologist, pharmacist and clinicians come together to learn the state-of-the-art in both basic sciences and clinical work. Metals in Medicine is a rapidly developing field documented with several key drugs, such as cisplatin in oncology, MRI contrast agents, Cardiolyte radiopharmaceutical imaging agents and nanoscience applications. These novel and unconventional approaches to fighting disease require multidisciplinary connectivity to validate the results needed by researchers to develop in laboratories and clinical settings alike. The meeting will feature both current clinical practices and discovery-level research in the following seven health-related areas: Oncology, Diagnostics/Imaging, Nuclear Medicine, Infectious and Neurodegenerative Diseases, Metabolic Disorders, Cardiovascular Malady, and Aging.
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METALLOBIOCHEMISTRY OF VANADIUM-V
  • 批准号:
    3467188
  • 项目类别:
  • 资助金额:
    $8.88万
  • 财政年份:
    1989
  • 负责人:
    DEBBIE Catharina CRANS
  • 依托单位:
METALLOBIOCHEMISTRY OF VANADIUM(V)
  • 批准号:
    3467189
  • 项目类别:
  • 资助金额:
    $9.32万
  • 财政年份:
    1989
  • 负责人:
    DEBBIE Catharina CRANS
  • 依托单位:
METALLOBIOCHEMISTRY OF VANADIUM(V)
  • 批准号:
    2180401
  • 项目类别:
  • 资助金额:
    $14.42万
  • 财政年份:
    1989
  • 负责人:
    DEBBIE Catharina CRANS
  • 依托单位:
METALLOBIOCHEMISTRY OF VANADIUM(V)
  • 批准号:
    2180400
  • 项目类别:
  • 资助金额:
    $15.55万
  • 财政年份:
    1989
  • 负责人:
    DEBBIE Catharina CRANS
  • 依托单位:
海外基金