2010 Biomolecular Interactions & Methods GRC & GRS

2010 生物分子相互作用

• 批准号: 7800232
• 负责人: Karen G. Fleming
• 金额: $ 0.5万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-12-01 至 2010-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7800232
• 关键词: Address; Area; Arts; Binding; Biological; Biological Process; Biophysics; Cell physiology; Cellular biology; Collaborations; Complement; Complex; Disease; Educational process of instructing; Elements; Environment; Future; Goals; Health; Human; Joints; Knowledge; Mass Spectrum Analysis; Methodology; Methods; Molecular; Molecular Biology; Motion; Postdoctoral Fellow; Process; Protein Dynamics; Proteins; Published Comment; Research; Research Personnel; Ribosomes; Scientist; System; Technology; Therapeutic Intervention; Work; abstracting; base; biological systems; experience; human disease; meetings; molecular dynamics; novel; posters; pre-doctoral; symposium; theories

DESCRIPTION (provided by applicant): This proposal seeks partial support for joint Gordon Conference meetings: (1) the Gordon Research Conference on Biomolecular Interactions and Methods (Jan 17-22, 2010); and/or (2) its accompanying Gordon Research Symposium, which is organized by and for pre- and postdoctoral scientists (Jan 16-17, 2010). Both meetings will take place in Galveston, TX at the same venue, and we anticipate that many of the young scientists attending the GRS will also participate in the subsequent GRC. The broad and long-term goal of these meetings is to advance our quantitative understanding of biomolecular complexes so that we may characterize the molecular basis for biological functions, disease, and therapeutic intervention. The theme of the 2010 meetings, Protein Interaction Dynamics: Theory, Methods, and Practice, will explore the state-of-the-art for characterizing protein dynamics, the effect of protein motions on binding interactions, and the dynamics of molecular associations in biological systems. Dr. Jamie Williamson (Scripps) will present a keynote address on his pioneering research that pushes mass spectrometry technology to address the contemporary problem of ribosome assembly. In addition, the meeting includes nine scientific sessions with both invited speakers as well as presentations from submitted abstracts; lively and highly interactive poster sessions complement the formal presentations. In 2010, the main conference will be preceded by a weekend meeting planned by and for post-doctoral and pre-doctoral trainees in the field of cell biology and biothermodynamics. This meeting, the Gordon-Kenan Graduate Research Seminar on Biomolecular Interactions & Methods, will provide a forum for these future leaders in the field to present their work in talks and posters, in a collegial and interactive environment that will add outstanding value to their overall GRC experience. This meeting provides a unique opportunity for scientists to focus on the highly interdisciplinary subject of protein interaction dynamics in a discussion-oriented meeting. The health relatedness of this application is that biomolecular interactions underlie all biological processes, and detailed knowledge of these processes is critical for understanding the molecular basis of disease and developing new therapies.

描述（由申请人提供）：本提案寻求对戈登会议联合会议的部分支持：（1）戈登生物分子相互作用和方法研究会议（2010年1月17日至22日）;和/或（2）由博士前和博士后科学家组织的戈登研究研讨会（2010年1月16日至17日）。这两次会议将在德克萨斯州的加尔维斯顿举行，我们预计许多参加GRS的年轻科学家也将参加随后的GRC。这些会议的广泛和长期目标是促进我们对生物分子复合物的定量理解，以便我们可以表征生物功能，疾病和治疗干预的分子基础。2010年会议的主题，蛋白质相互作用动力学：理论，方法和实践，将探讨最先进的表征蛋白质动力学，蛋白质运动对结合相互作用的影响，以及生物系统中分子缔合的动力学。Jamie威廉姆森博士（Scripps）将就他的开创性研究发表主题演讲，该研究推动质谱技术解决核糖体组装的当代问题。此外，会议还包括9场科学会议，邀请演讲者以及提交的摘要介绍;生动和高度互动的海报会议补充了正式演讲。2010年，在主要会议之前，将举行一次周末会议，由细胞生物学和生物热力学领域的博士后和博士前受训人员计划并为其举办。这次会议，戈登凯南研究生研究研讨会生物分子相互作用和方法，将提供一个论坛，为这些未来的领导者在该领域提出他们的工作在会谈和海报，在一个合议和互动的环境，将增加突出的价值，他们的整体GRC经验。这次会议为科学家提供了一个独特的机会，在一个以讨论为导向的会议上专注于蛋白质相互作用动力学的高度跨学科的主题。该应用的健康相关性在于，生物分子相互作用是所有生物过程的基础，并且这些过程的详细知识对于理解疾病的分子基础和开发新疗法至关重要。