STRUCTURAL CHARACTERIZATION OF SULFATED STEROIDS THAT ACTIVATE MOUSE

激活小鼠的硫酸类固醇的结构表征

• 批准号: 8168783
• 负责人: FONG-FU HSU
• 金额: $ 1.13万
• 依托单位: WASHINGTON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-03-10 至 2010-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8168783
• 关键词: Chemicals; Computer Retrieval of Information on Scientific Projects Database; Cues; Female; Funding; Grant; Insecta; Institution; Mammals; Mus; Neurons; Pheromone; Research; Research Personnel; Resources; Signal Transduction; Social Behavior; Social Identification; Source; United States National Institutes of Health; Urine; steroid sulfate; vomeronasal organ

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. In many species, social behavior is organized via chemical signaling. While many of these signals have been identified for insects, the chemical identity of these social cues (often called pheromones) for mammals is largely unknown. We recently isolated these chemical cues that caused firing in the pheromone-sensing neurons of the vomeronasal organ from female mouse urine (1).

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 在许多物种中，社会行为是通过化学信号来组织的。虽然这些信号中的许多已经在昆虫身上被识别出来，但对于哺乳动物来说，这些社交信号(通常被称为信息素)的化学特性在很大程度上是未知的。我们最近从雌性小鼠的尿液中分离出了这些化学线索，这些化学线索导致了犁鼻器信息素感觉神经元的放电(1)。