ELECTROSPRAY IONIZATION WITH LOW-ENERGY COLLISIONALLY ACTIVATED DISSOCIATION

低能碰撞激活解离的电喷雾电离

• 批准号: 8168803
• 负责人: FONG-FU HSU
• 金额: $ 1.13万
• 依托单位: WASHINGTON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-03-10 至 2010-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8168803
• 关键词: Acids; Computer Retrieval of Information on Scientific Projects Database; Dissociation; Electrospray Ionization; Funding; Glycerophospholipids; Grant; Institution; Mass Fragmentography; Research; Research Personnel; Resources; Source; United States National Institutes of Health; diglycerol phosphate; glycerophosphoethanolamine; glycerophosphoserine; glycerylphosphoinositol

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This review describes the use of low-energy collisionally activated dissociation (CAD) with both tandem quadrupole and ion-trap mass spectrometry toward structural characterization of glycerophospholipids (GPLs), including classes of glycerophosphocholine, glycerophosphoethanolamine, glycerophosphoserine, glycerophosphoglycerol glycerophosphoinositol and glycerophosphatidic acid, as well as their lyso-, plasmanyl-, and plasmenylphospholipid subclasses.

该子项目是利用该技术的众多研究子项目之一 资源由 NIH/NCRR 资助的中心拨款提供。子项目和 研究者 (PI) 可能已从 NIH 的另一个来源获得主要资金， 因此可以在其他 CRISP 条目中表示。列出的机构是 对于中心来说，它不一定是研究者的机构。 本综述描述了使用低能碰撞激活解离 (CAD) 结合串联四极杆和离子阱质谱来表征甘油磷脂 (GPL)，包括甘油磷酸胆碱、甘油磷酸乙醇胺、甘油磷酸丝氨酸、甘油磷酸甘油甘油磷酸肌醇 和甘油磷脂酸，以及它们的溶血磷脂、血浆磷脂和血浆磷脂亚类。