ELECTROSPRAY IONIZATION WITH LOW-ENERGY COLLISIONALLY ACTIVATED DISSOCIATION

低能碰撞激活解离的电喷雾电离

• 批准号: 8361400
• 负责人: FONG-FU HSU
• 金额: $ 1.75万
• 依托单位: WASHINGTON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-01-01 至 2011-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8361400
• 关键词: Acids; Dissociation; Electrospray Ionization; Funding; Glycerophospholipids; Grant; Mass Fragmentography; Mass Spectrum Analysis; National Center for Research Resources; Principal Investigator; Research; Research Infrastructure; Resources; Source; United States National Institutes of Health; biomedical resource; cost; diglycerol phosphate; glycerophosphoethanolamine; glycerophosphoserine; glycerylphosphoinositol

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. This review describes the use of low-energy collisionally activated dissociation (CAD) with both tandem quadrupole and ion-trap mass spectrometry toward structural characterization of glycerophospholipids (GPLs), including classes of glycerophosphocholine, glycerophosphoethanolamine, glycerophosphoserine, glycerophosphoglycerol glycerophosphoinositol and glycerophosphatidic acid, as well as their lyso-, plasmanyl-, and plasmenylphospholipid subclasses.

这个子项目是许多利用资源的研究子项目之一 由NIH/NCRR资助的中心拨款提供。子项目的主要支持 而子项目的主要调查员可能是由其他来源提供的， 包括其它NIH来源。 列出的子项目总成本可能 代表子项目使用的中心基础设施的估计数量， 而不是由NCRR赠款提供给子项目或子项目工作人员的直接资金。 本文介绍了使用低能量碰撞活化解离（CAD）与串联四极杆和离子阱质谱对甘油磷脂（GPLs）的结构表征，包括类的甘油磷酸胆碱，甘油磷酸乙醇胺，甘油磷酸丝氨酸，甘油磷酸甘油磷酸肌醇和甘油磷脂酸，以及它们的lyso-，plasmanyl-和plasmenylphospholipid的子类。