ELECTROSPRAY IONIZATION WITH LOW-ENERGY COLLISIONALLY ACTIVATED DISSOCIATION

低能碰撞激活解离的电喷雾电离

• 批准号: 8361400
• 负责人: FONG-FU HSU
• 金额: $ 1.75万
• 依托单位: WASHINGTON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-01-01 至 2011-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8361400
• 关键词: Acids; Dissociation; Electrospray Ionization; Funding; Glycerophospholipids; Grant; Mass Fragmentography; Mass Spectrum Analysis; National Center for Research Resources; Principal Investigator; Research; Research Infrastructure; Resources; Source; United States National Institutes of Health; biomedical resource; cost; diglycerol phosphate; glycerophosphoethanolamine; glycerophosphoserine; glycerylphosphoinositol

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. This review describes the use of low-energy collisionally activated dissociation (CAD) with both tandem quadrupole and ion-trap mass spectrometry toward structural characterization of glycerophospholipids (GPLs), including classes of glycerophosphocholine, glycerophosphoethanolamine, glycerophosphoserine, glycerophosphoglycerol glycerophosphoinositol and glycerophosphatidic acid, as well as their lyso-, plasmanyl-, and plasmenylphospholipid subclasses.

这个子项目是利用资源的许多研究子项目之一。 由NIH/NCRR资助的中心拨款提供。对子项目的主要支持 子项目的首席调查员可能是由其他来源提供的， 包括美国国立卫生研究院的其他来源。为子项目列出的总成本可能 表示该子项目使用的中心基础设施的估计数量， 不是由NCRR赠款提供给次级项目或次级项目工作人员的直接资金。 本文介绍了用低能碰撞激活解离(CAD)串联四极杆和离子陷阱质谱仪来表征甘油磷脂的结构，包括甘油磷胆碱、甘油磷乙醇胺、甘油磷脂丝氨酸、甘油磷脂肌醇和甘油磷脂酸，以及它们的甘油磷脂亚类、质膜基磷脂亚类和质膜磷脂亚类。