STRUCTURAL CHARACTERIZATION OF SULFATED STEROIDS THAT ACTIVATE MOUSE

激活小鼠的硫酸类固醇的结构表征

• 批准号: 7954032
• 负责人: FONG-FU HSU
• 金额: $ 0.35万
• 依托单位: WASHINGTON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-02-01 至 2010-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7954032
• 关键词: A Mouse; Chemicals; Computer Retrieval of Information on Scientific Projects Database; Cues; Female; Funding; Grant; Insecta; Institution; Mammals; Mass Spectrum Analysis; Mus; Neurons; Pheromone; Research; Research Personnel; Resources; Signal Transduction; Social Behavior; Social Identification; Source; United States National Institutes of Health; Urine; biomedical resource; steroid sulfate; vomeronasal organ

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. In many species, social behavior is organized via chemical signaling. While many of these signals have been identified for insects, the chemical identity of these social cues (often called pheromones) for mammals is largely unknown. We recently isolated these chemical cues that caused firing in the pheromone-sensing neurons of the vomeronasal organ from female mouse urine (1).

这个子项目是许多利用 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 中心，但不一定是研究者所在的机构。 在许多物种中，社会行为是通过化学信号来组织的。虽然许多这些信号已经确定为昆虫，这些社会线索（通常称为信息素）的哺乳动物的化学身份在很大程度上是未知的。我们最近从雌性小鼠尿液中分离出这些化学线索，这些化学线索导致犁鼻器的信息素感应神经元放电（1）。