Administrative Core

密歇根州立大学肠道研究调查网络合作研究中心(MSU Erin CRC)是一个多学科、高度集成的研究中心，研究肠道微生物群在健康和疾病中的作用，以了解和缓解腹泻疾病。ERIN中心将围绕三个交叉研究主题领域组成：研究领域1-微生物生态：阐明肠道微生物区系在病原体抗性中的作用；研究区域2-宿主反应：空肠弯曲杆菌介导的(HU)微生物区系小鼠模型中的自身免疫性神经病；以及研究区域3-临床研究：微生物群组成、多样性和功能对肠道疾病的影响。MSU-ERIN的PI 该中心的五名核心负责人是琳达·曼斯菲尔德博士；核心负责人是玛格丽特·尼古拉斯女士；他们将共同组成行政核心小组(ACT)。由研究区领导层组成的内部咨询委员会将就研究事项向私人投资提供建议。一个由研究计划涵盖的三个领域的资深专家组成的外部科学顾问/委员会将发挥咨询和指导作用；该委员会将指导密歇根州立大学ERIN CRC，使其走上研究的轨道 进度和目标，并帮助保持计划的完整性。ACT将负责协调拟议的三个专题领域的研究工作，建立和保持研究质量、生产力和卓越，并确保以最快的方式实现ERIN的目的和目标；ACT还将发挥中央沟通和管理职能，将所有研究项目统一在一个行政保护伞下。地方执行委员会(LEC)将是密歇根州立大学Erin CRC的决策机构。它将由三个专题研究领域的负责人、负责专题平衡的指定个人调查员以及核心领导财政行政和核心协调员组成；地方经济委员会将协助ERIN的所有方面：科学、财务和行政。因此，密歇根州立大学ERIN-CRC的组织结构由行政核心和研究区领导组成，这两个领导共同组成了地方执行委员会(LEC)。以及三个研究区团队。All Erin小组是整个内部研究团队，只是不包括外部科学咨询委员会。ERIN-CRC的跨职能结构的设计旨在促进交流和互动的小组研究，并促进协同、创新和持续改进。

The Michigan State University Enterics Research Investigational Network, Cooperative Research Center (MSU ERIN CRC) is a mulfidisciplinary, highly integrated Research Center to study the enteric microbiome in health and disease to understand and alleviate diarrheal illness. The ERIN Center will be organized around three cross-cutting research thematic areas consisfing of: Research Area 1-Microbial Ecologv: Elucidating the role of the intestinal microbiota in pathogen resistance; Research Area 2 -Host Response: Campylobacter jejuni-mediated autoimmune neuropathies in (Hu) microbiota mouse models; and Research Area 3-Clinical Research: The impact of microbiome composition, diversity and function on enteric disease. The PI of MSU-ERIN Center is Dr. Linda Mansfield who will also serve as its Administrafive Core Leader; the Core Leader Fiscal Administrator and Core Coordinator will be Ms. Margaret Nicholas; together they will form the Administrative Core Team (ACT). An internal advisory committee consisfing of the Research Area Leadership will advise the PI on research matters. An Extemal Science Advison/ Committee made up of senior experts in the three fields covered by the research plan¿microbial ecology, host response/ immunology, and human clinical research/diagnosfics¿will act in an advisory and steering capacity; the committee will guide the MSU ERIN CRC, keep it on track for research progress and goals, and help to maintain program integrity. The ACT will be responsible for coordinating the research efforts of the three proposed thematic areas, establishing and maintaining research quality, productivity and excellence, and ensuring the delivery of ERIN aims and objectives in a fimely fashion; the ACT will also serve a central communications and management function uniting all research projects under one administrative umbrella. The Local Executive Committee (LEC) will be the decision making body for the MSU ERIN CRC. It will consist of the PI, leaders of three thematic research areas, designated individual investigators for theme balance, and the Core Leader Fiscal Administrative & Core Coordinator; the LEC will assist with all aspects of ERIN: scientific, financial, and administrative. Thus, the organizational structure of the MSU ERIN-CRC consists of the Administrative Core and the Research Area Leadership, which together forms the Local Executive Committee (LEC). and the three Research Area Teams. The All ERIN group is the entire Internal Research Team only excluding the External Science Advisory Committee. The cross-functional structure of the ERIN-CRC has been so designed as to facilitate communication and interactive group research and to promote synergy, innovation, and continuous improvement.