Administrative Core

密歇根州立大学肠道研究网络合作研究中心 (MSU ERIN CRC) 是一个多学科、高度综合的研究中心，致力于研究健康和疾病中的肠道微生物组，以了解和缓解腹泻疾病。 ERIN 中心将围绕三个交叉研究主题领域进行组织，包括： 研究领域 1-微生物生态：阐明肠道微生物群在病原体抵抗力中的作用；研究领域 2 - 宿主反应：（Hu）微生物群小鼠模型中空肠弯曲菌介导的自身免疫性神经病；研究领域3-临床研究：微生物组的组成、多样性和功能对肠道疾病的影响。 MSU-ERIN 的 PI 中心由 Linda Mansfield 博士担任，她也将担任其行政核心领导者；核心领导人财政管理员和核心协调员将是玛格丽特·尼古拉斯女士；他们将共同组成行政核心团队（ACT）。由研究领域领导层组成的内部咨询委员会将就研究事项向 PI 提供建议。由研究计划涵盖的三个领域——微生物生态学、宿主反应/免疫学和人类临床研究/诊断——的资深专家组成的外部科学顾问/委员会将发挥咨询和指导作用；该委员会将指导 MSU ERIN CRC，使其保持研究正轨 进度和目标，并有助于保持计划的完整性。 ACT 将负责协调三个拟议主题领域的研究工作，建立和维持研究质量、生产力和卓越性，并确保及时实现 ERIN 的宗旨和目标； ACT 还将发挥中央通信和管理职能，将所有研究项目统一在一个行政管理框架下。地方执行委员会 (LEC) 将成为 MSU ERIN CRC 的决策机构。该小组将由 PI、三个主题研究领域的领导者、负责主题平衡的指定个人调查员以及核心领导者、财政行政和核心协调员组成； LEC 将在 ERIN 的各个方面提供协助：科学、财务和行政。因此，MSU ERIN-CRC 的组织结构由行政核心和研究领域领导层组成，它们共同组成了地方执行委员会 (LEC)。以及三个研究领域团队。 All ERIN 小组是整个内部研究团队，仅不包括外部科学咨询委员会。 ERIN-CRC 的跨职能结构旨在促进沟通和互动小组研究，并促进协同、创新和持续改进。

The Michigan State University Enterics Research Investigational Network, Cooperative Research Center (MSU ERIN CRC) is a mulfidisciplinary, highly integrated Research Center to study the enteric microbiome in health and disease to understand and alleviate diarrheal illness. The ERIN Center will be organized around three cross-cutting research thematic areas consisfing of: Research Area 1-Microbial Ecologv: Elucidating the role of the intestinal microbiota in pathogen resistance; Research Area 2 -Host Response: Campylobacter jejuni-mediated autoimmune neuropathies in (Hu) microbiota mouse models; and Research Area 3-Clinical Research: The impact of microbiome composition, diversity and function on enteric disease. The PI of MSU-ERIN Center is Dr. Linda Mansfield who will also serve as its Administrafive Core Leader; the Core Leader Fiscal Administrator and Core Coordinator will be Ms. Margaret Nicholas; together they will form the Administrative Core Team (ACT). An internal advisory committee consisfing of the Research Area Leadership will advise the PI on research matters. An Extemal Science Advison/ Committee made up of senior experts in the three fields covered by the research plan¿microbial ecology, host response/ immunology, and human clinical research/diagnosfics¿will act in an advisory and steering capacity; the committee will guide the MSU ERIN CRC, keep it on track for research progress and goals, and help to maintain program integrity. The ACT will be responsible for coordinating the research efforts of the three proposed thematic areas, establishing and maintaining research quality, productivity and excellence, and ensuring the delivery of ERIN aims and objectives in a fimely fashion; the ACT will also serve a central communications and management function uniting all research projects under one administrative umbrella. The Local Executive Committee (LEC) will be the decision making body for the MSU ERIN CRC. It will consist of the PI, leaders of three thematic research areas, designated individual investigators for theme balance, and the Core Leader Fiscal Administrative & Core Coordinator; the LEC will assist with all aspects of ERIN: scientific, financial, and administrative. Thus, the organizational structure of the MSU ERIN-CRC consists of the Administrative Core and the Research Area Leadership, which together forms the Local Executive Committee (LEC). and the three Research Area Teams. The All ERIN group is the entire Internal Research Team only excluding the External Science Advisory Committee. The cross-functional structure of the ERIN-CRC has been so designed as to facilitate communication and interactive group research and to promote synergy, innovation, and continuous improvement.