WANPRC MACACA NEMESTRINA SPF BREEDING COLONY
WANPRC 猕猴桃 SPF 育种群
基本信息
- 批准号:8356908
- 负责人:
- 金额:$ 184.47万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2011
- 资助国家:美国
- 起止时间:2011-07-01 至 2012-06-30
- 项目状态:已结题
- 来源:
- 关键词:Acquired Immunodeficiency SyndromeAnimalsBiomedical ResearchBreedingDiagnosticEnsureEvaluationFoundationsFundingGrantHousingHuman ResourcesImmunologyInstitutionLaboratoriesLocal MicrobicidesMacacaMacaca nemestrinaMaintenanceMorbidity - disease rateNational Center for Research ResourcesPathogenesisPrimatesPrincipal InvestigatorProcessResearchResearch InfrastructureResearch PersonnelResourcesSIVSolidSourceSpecific Pathogen FreesTexasTherapeutic AgentsTuberculosisUnited States National Institutes of HealthViralWashingtonanimal breedingcostgerm free conditionlaboratory facilitymeetingsmortalitypublic health relevancetransmission processvaccine developmentvirology
项目摘要
This subproject is one of many research subprojects utilizing the resources
provided by a Center grant funded by NIH/NCRR. Primary support for the subproject
and the subproject's principal investigator may have been provided by other sources,
including other NIH sources. The Total Cost listed for the subproject likely
represents the estimated amount of Center infrastructure utilized by the subproject,
not direct funding provided by the NCRR grant to the subproject or subproject staff.
DESCRIPTION (provided by applicant): Macaca nemestrina are an invaluable resource for AIDS-related studies in vaccine development, therapeutic agent discovery, topical microbicide evaluation, and basic lentiviral virology, pathogenesis and immunology. The Washington National Primate Research Center (WaNPRC) seeks support to extend maintenance and continue expansion of the existing M. nemestrina specific pathogen-free breeding (SPF) colony. This colony is free of several viral agents (SIV, SRV, STLV, CHV) and tuberculosis. We seek support to expand the colony to more fully meet NIH research needs at WaNPRC and elsewhere. This proposal extends successful management and housing practices developed over the course of the previous grant which provide a solid, proven foundation for continued expansion of the colony. The existing SPF animals will be relocated as needed to consolidate the SPF M. nemestrina breeding colony at the Shin Nippon Biomedical Laboratory facility at Alice, Texas. Virologic surveillance will continue to be provided by the WaNPRC Diagnostic Laboratory and management will continue as an integrated process between WaNPRC and SNBL personnel. This foundation will be expanded to ensure continued successful expansion of this important SPF macaque colony.
PUBLIC HEALTH RELEVANCE (provided by applicant): The M. nemestrina is an important, highly relevant species for AIDS-related biomedical research. Animals from this SPF colony are distributed widely; the majority provided to Affiliate Investigators, and significant numbers provided to other collaborative institutions. Additionally, SPF animals significantly limit the potential morbidity and/or mortality associated with zoonotic CHV transmission.
这个子项目是利用这些资源的众多研究子项目之一
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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DAVID M ANDERSON其他文献
DAVID M ANDERSON的其他文献
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{{ truncateString('DAVID M ANDERSON', 18)}}的其他基金
29th Annual Symposium for Nonhuman Primate Models for AIDS
第29届非人类灵长类艾滋病模型年度研讨会
- 批准号:
8196705 - 财政年份:2011
- 资助金额:
$ 184.47万 - 项目类别:
COMPARISON OF VACCINE REGIMENS: HIV-SIV RECOMBINANTS WITH PROTEIN BOOSTING
疫苗方案的比较:具有蛋白质增强作用的 HIV-SIV 重组体
- 批准号:
8357622 - 财政年份:2011
- 资助金额:
$ 184.47万 - 项目类别:
MECHANISM OF PROTECTIVE IMMUNITY INDUCED BY EBOLA VACCINES
埃博拉疫苗诱导保护性免疫的机制
- 批准号:
8357611 - 财政年份:2011
- 资助金额:
$ 184.47万 - 项目类别:
POST-EXPOSURE MONITORING OF LENTIVIRUS-INFECTED MACAQUES
慢病毒感染猕猴的暴露后监测
- 批准号:
8357594 - 财政年份:2011
- 资助金额:
$ 184.47万 - 项目类别:
MECHANISM OF PROTECTIVE IMMUNITY INDUCED BY EBOLA VACCINES
埃博拉疫苗诱导保护性免疫的机制
- 批准号:
8172781 - 财政年份:2010
- 资助金额:
$ 184.47万 - 项目类别:
POST-EXPOSURE MONITORING OF LENTIVIRUS-INFECTED MACAQUES
慢病毒感染猕猴的暴露后监测
- 批准号:
8172754 - 财政年份:2010
- 资助金额:
$ 184.47万 - 项目类别:
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