Training Program in Microbial Pathogenesis

描述(由申请人提供)：本申请是犹他大学2003年授予的微生物致病培训计划的续展申请。该奖项的头五年成功地实现了犹他大学加强和促进微生物致病作用的目标，并为研究生和博士后研究员提供了新的培训机会。综合方法涉及来自不同部门和学科的实验室，为受训人员带来了高水平的科学交流。拥有微生物学、免疫学和宿主反应、传染病/流行病学、艾滋病毒生物学、病原体传播生态学和病原体易感性遗传学基础的教职员工现在定期参加由培训赠款赞助的活动。该奖项的第一期成果是：1)开发了微生物病原学和免疫学的新课程；2)增加了受训人员与微生物致病研讨会系列演讲者的互动；3)成立了一个新的微生物致病学期刊俱乐部；以及4)启动了年度培训补助金务虚会，学员和外部专家演讲者发表了演讲。这些计划已经扩展到微生物致病社区作为一个整体。这一重新提交提供了更多的重点计划，以监测学员的成功和项目活动，并为学员在微生物致病学未来的职业生涯做准备。这包括内部和外部审查，以及学员和导师的正式反馈。我们继续强调科学严谨的出版物的重要性，以及提供大量学术和职业建议的机会。学员准备影响健康和研究的重要领域，包括新出现的传染病、宿主-病原体相互作用的分子遗传学、分子病毒学和流行病学，以及免疫反应在宿主防御和感染的病理结果中的参与。已离开培训补助金的受训人员目前在研究或学术领域担任职务。基于第一个奖项的成功，我们请求继续支持3名博士后和3名博士后实习生。 相关性：微生物病原学作为一门学科涵盖了感染病原体与人类或动物宿主之间的关键相互作用。了解这些相互作用的分子方面对于健康相关传染病研究的许多方面都很重要，包括分子发病机制、疫苗开发、治疗方法和流行病学。我们项目的实习生对这些补品有广泛的接触，并接受了这一领域的高级研究人员的培训。

DESCRIPTION (provided by applicant): This application is a resubmission for renewal of the Training Program in Microbial Pathogenesis at the University of Utah awarded in 2003. The first five years of this award successfully accomplished the goals of enhancing and promoting Microbial Pathogenesis at the University of Utah and providing new training opportunities for graduate students and postdoctoral fellows. An integrated approach, involving laboratories from different departments and disciplines, has resulted in a high level of scientific exchange for the trainees. Faculty with foundations in microbiology, immunology and host responses, infectious disease/epidemiology, HIV biology, ecology of pathogen transmission, and genetics of susceptibility to pathogens, now interact on a regular basis at Training Grant-sponsored events. The first period of the award has resulted in: 1) the development of new courses in Microbial Pathogenesis and Immunology; 2) increased interaction of trainees with speakers at the Microbial Pathogenesis Seminar Series; 3) formation of a new journal club in Microbial Pathogenesis; and 4) the initiation of an Annual Training Grant Retreat with trainee presentations and those of outside expert speakers. These programs have extended to the Microbial Pathogenesis community as a whole. This resubmission provides greater emphasis on plans for monitoring trainee success and program activities, and in preparing trainees for future careers in Microbial Pathogenesis. This included internal and external reviews, and formal feedback from trainees and mentors. We continue to emphasize the importance of scientifically rigorous publications, along with numerous opportunities for academic and career advice. Trainees are prepared to impact important areas of health and research including emerging infectious diseases, molecular genetics of host-pathogen interactions, molecular virology and epidemiology, and involvement of immune responses in host defense and pathological outcomes of infection. AH trainees who have left the Training Grant currently hold positions in research or academics. Based on the success of the first award, we are requesting continued support for 3 pre-doctoral and 3 postdoctoral trainees. RELEVANCE: Microbial Pathogenesis as a discipline covers the critical interactions between infectious pathogens and the human or animal host. Understanding the molecular aspects of these interactions is important for many aspects of health related infectious disease research including molecular pathogenesis, vaccine development, therapeutic cures, and epidemiology. Trainees in our program have a broad exposure to these tonics and are trained as sophisticated investigators in this area.