From Cells to Systems and Applications: Computational Neuroscience Training at Em

从细胞到系统和应用：EM 的计算神经科学培训

• 批准号: 8211805
• 负责人: DIETER JAEGER
• 金额: $ 8.93万
• 依托单位: EMORY UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-08-15 至 2016-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8211805
• 关键词: Address; Behavioral; Biological; Biological Sciences; Biology; Biomedical Engineering; Cells; Computer Simulation; Computing Methodologies; DNA Sequencing Facility; Disease; Education; Educational Curriculum; Educational process of instructing; Engineering; Epilepsy; Faculty; Fellowship; Funding; Grant; Individual; Institution; Joints; Link; Medical; Neurobiology; Neurosciences; Parkinson Disease; Principal Investigator; Qualifying; Recruitment Activity; Research; Research Personnel; Research Project Grants; Stretching; Students; System; Touch sensation; Training; Training Programs; United States National Institutes of Health; Work; cohort; computational neuroscience; disease mechanisms study; graduate student; interest; planetary Atmosphere; programs; relating to nervous system; research study; web site

DESCRIPTION (provided by applicant): Emory and Georgia Tech have steadily grown the number of faculty involved in computational neuroscience over the past 15 years. The research of these faculty stretch from cellular to systems and theoretical approaches. In 1997 the two Institutions formed a joint Department of Biomedical Engineering, further strengthening the highly collaborative atmosphere between researchers on both campuses. In addition both campuses have a strong track record both in undergraduate and graduate teaching. The proposed training program in computational neuroscience aims to capitalize on these strengths by formalizing an integrated approach to class work and research on both undergraduate and graduate levels. The strong NIH and NSF funded research programs of more than 15 principal investigators identified as computational neuroscientists range from detailed cellular computer simulations of neural dynamics to engineering approaches and the quantitative study of disease mechanisms underlying important disorders such as epilepsy and Parkinson's disease using computational methods. Therefore students will be exposed to multiple levels of approaches aimed ultimately at addressing medical questions. A highly qualified and diverse applicant pool for student fellowships under this program exists on both undergraduate and graduate levels, and will bring some applicants with a primarily background in the biological sciences to integrate computational approaches into their research, and vice versa brings more computational or theoretically oriented applicants in touch with biological experimental research. The program encompasses a cohort of 6 undergraduate and 6 graduate student fellows, who will absolve a rigorous curriculum in neurobiology and mathematical and computational methods through a core sequence of required classes as well as individually chosen electives. Undergraduate fellows will be funded for a period of two years in their junior and senior years, during which they will undertake specialized class work and research in a computational neuroscience lab. Undergraduate trainees will be primarily recruited from the Emory Neuroscience and Behavioral Biology and the Georgia Tech Biomedical Engineering majors, who bring a biological and quantitative strength to the program, respectively. Over 200 students join these majors annually, and we will only take applicants with a GPA of 3.5 or better and expressing an interest in future research graduate training. The graduate students in this program will be recruited from the applicant pools for the Neuroscience and Biomedical Engineering programs, which together receive more than 120 highly qualified applications each year. A special track for fellows in computational neuroscience will be announced on the program websites that will also link to an extensive independent website describing this program. Graduate students will be funded for the first two years of their education, and then obtain individual training grants or be funded by research grants. PHS 398/2590 (Rev. 06/09) Page Continuation Format Page PUBLIC HEALTH RELEVANCE: The use of computational approaches is becoming more and more important in biomedical research as the myriad of fact that we collect as scientists need to be put back together to enable a synthetic understanding of functioning systems. The training program "From Cells to Systems and Applications: Computational Neuroscience Training at Emory & Georgia Tech" makes a significant contribution to fulfilling the need for highly trained scientists capable of integrating experimental results using computational and theoretical approaches. A new generation of scientists with an integrated training in computational neuroscience graduating from this program will raise our level of being able to simulate and understand the complexity of brain processes underlying neurological and psychiatric diseases.

描述（由申请人提供）：埃默里大学和格鲁吉亚理工学院在过去的15年里稳步增加了参与计算神经科学的教师人数。这些教师的研究从细胞延伸到系统和理论方法。1997年，两个机构成立了生物医学工程联合系，进一步加强了两个校区研究人员之间的高度合作气氛。此外，两个校区在本科和研究生教学方面都有很好的记录。拟议的计算神经科学培训计划旨在通过正式确定本科和研究生水平的课堂工作和研究的综合方法来利用这些优势。强大的NIH和NSF资助了超过15名被确定为计算神经科学家的主要研究人员的研究计划，范围从神经动力学的详细细胞计算机模拟到工程方法以及使用计算方法对癫痫和帕金森病等重要疾病的疾病机制进行定量研究。因此，学生将接触到多层次的方法，旨在最终解决医学问题。一个高素质和多样化的申请人池学生奖学金根据这个程序存在于本科和研究生水平，并将带来一些申请人在生物科学的主要背景，以整合计算方法到他们的研究，反之亦然带来更多的计算或理论导向的申请人接触生物实验研究。该计划包括6名本科生和6名研究生研究员，他们将通过必修课程的核心序列以及单独选择的选修课来免除神经生物学和数学和计算方法的严格课程。本科研究员将在大三和大四获得为期两年的资助，在此期间，他们将在计算神经科学实验室进行专业的课堂工作和研究。本科学员将主要从埃默里神经科学和行为生物学和格鲁吉亚科技生物医学工程专业招募，他们分别为该计划带来生物和定量优势。每年有200多名学生加入这些专业，我们只接受GPA为3.5或更高并对未来的研究生培训感兴趣的申请人。该项目的研究生将从神经科学和生物医学工程项目的申请人中招募，这些项目每年共收到120多份高质量的申请。计算神经科学研究员的一个特殊轨道将在该计划的网站上公布，这些网站也将链接到一个描述该计划的广泛的独立网站。研究生将在其教育的前两年获得资助，然后获得个人培训赠款或由研究赠款资助。PHS 398/2590（Rev.06/09） 公共卫生相关性：计算方法的使用在生物医学研究中变得越来越重要，因为我们作为科学家收集的无数事实需要重新组合在一起，以实现对功能系统的综合理解。培训计划“从细胞到系统和应用：埃默里和格鲁吉亚理工学院的计算神经科学培训”为满足对训练有素的科学家的需求做出了重大贡献，这些科学家能够使用计算和理论方法整合实验结果。从该计划毕业的新一代科学家在计算神经科学方面接受了综合培训，这将提高我们模拟和理解神经和精神疾病背后大脑过程复杂性的水平。