Medical Scientist Training Program - Ohio State University

描述（由申请人提供）：学术医学的基本使命是获取和应用科学知识，以改善医疗保健。为了使医疗企业有效运作，对于学术生物医学界来说，拥有接受特殊培训的医生-科学家至关重要，这些培训将严格的科学教育与最先进的医学教育相结合。这些人员促进了临床和实验室之间的互动，促进了对疾病机制的基础研究和导致临床应用的转化研究。因此，他们被定位为生物医学研究和教育界的领导者。在此MSTP应用程序中，我们描述了俄亥俄州州立大学（OSU）医学科学家计划（MSP），其目标是为MD-博士学员提供科学和医学教育的严谨性，深度和广度，以便于整合两套培训，为他们作为成功的医生科学家的职业生涯做好准备。为了实现这些目标，MSP作为一个合作伙伴计划，将创新的医学院课程与三个综合研究生课程联系起来，让学生在各个领域进行深入的科学探究。医学院的课程是使用OSU的独立学习计划完成的，这是一个独特的课堂独立学习课程，使学生能够使用结构化的目标和分布式信息源来学习临床前医学课程。与此同时，学生开始他们的博士培训，采取研究生课程在三个特定的程序之一，综合生物医学科学研究生课程（IBGP），神经科学研究生课程（NGSP），或生物医学工程（BME）。通过同时开始这两个领域的课程，学生可以获得比顺序学习材料更好的内容整合。此外，这种工程化的综合方法意味着学生在两年的课程结束时几乎完成了所有的课程。从第三年开始，学生可以将大部分时间投入到论文研究中，使他们能够以时间效率高的方式完成学业，通常持续8年。这个高度整合的MD-PhD课程吸引了大量优秀申请人的兴趣，我们每年都会填补5个职位。我们要求在5年内提供30个学生年的资金，从第一年的2个学生年开始，每年增加2个学生年，到第5年总共增加10个学生年。NIGMS对我们计划的认可将使我们能够招募最优秀和最聪明的学生，提高MSP培养未来领导者的能力，这些领导者将使俄亥俄州州立大学医学院实现其既定的使命：通过研究，教育和患者护理创新来改善人们的生活。 公共卫生相关性：所有NIH资助的研究的使命是改善这个国家的健康。由于MD-PhD学员具有基础科学到临床应用的连续性的专业知识，因此他们具有发现基本疾病机制并将这些发现带回临床的最佳技能。因此，致力于追求这条职业道路的学生应该得到培养，并被安置在俄亥俄州州立大学等培训环境中，使他们能够实现这些崇高的目标。NIGMS对这种培训的支持对于提供使这些未来的医生-科学家领导人蓬勃发展的环境至关重要。

DESCRIPTION (provided by applicant): The fundamental mission of academic medicine is the acquisition and application of scientific knowledge to improve health care. In order for the medical enterprise to function effectively, it is critically important for the academic biomedical community to have physician-scientists who receive special training that integrates both a rigorous scientific education with state-of-the-art medical education. These individuals facilitate interactions between the clinic and lab that promote both basic investigation on disease mechanisms and translational research leading to clinical applications. Thus, they are positioned to be leaders in biomedical research and educational communities. In this MSTP application, we describe The Ohio State University (OSU) Medical Scientist Program (MSP), whose objective is to provide MD-PhD trainees with the rigor, depth, and breadth of both scientific and medical education in a way that facilitates integrating both sets of training to prepare them for careers as successful physician-scientists. In order to achieve these goals, the MSP serves as a partnership program linking an innovative medical school curriculum with three integrated graduate programs to allow students to pursue in-depth scientific inquiry in a wide variety of areas. Medical school coursework is completed using OSU's Independent Study Program, a unique classroom- independent course of study which enables students to use structured objectives and distributed sources of information to learn the pre-clinical medical curriculum. At the same time, students begin their PhD training by taking graduate courses in one of three specific programs, the Integrated Biomedical Science Graduate Program (IBGP), the Neuroscience Graduate Studies Program (NGSP), or Biomedical Engineering (BME). By beginning coursework in both areas simultaneously, students receive much better integration of content than would be achieved by studying the material sequentially. In addition, this engineered integrated approach means that students have completed nearly all their coursework by the end of two years in the program. Beginning in the third year, students can devote the bulk of their time to their dissertation research, enabling them to complete their studies in a time-efficient manner typically lasting 8 years. This highly integrated MD-PhD program has attracted interest from a large pool of excellent applicants for the 5 positions that we fill annually. We are requesting funds for 30 student years of funding over 5 years beginning with 2 in the first year and adding 2 each year to a total of 10 in year 5. Recognition of our program by NIGMS will allow us to recruit the best and brightest students, enhancing the ability of the MSP to train the future leaders who will enable the Ohio State University College of Medicine to achieve its stated mission: To improve people's lives through innovation in research, education and patient care. PUBLIC HEALTH RELEVANCE: The mission of all NIH-funded research is the improvement of this nation's health. Since MD-PhD trainees have expertise in the continuum of basic science to clinical application, they have the optimal skill set to discover fundamental disease mechanisms and to bring these findings back to the clinic. Thus, students dedicated to pursuing this career path should be nurtured and placed in training environments such as the Ohio State University that will enable them to reach these lofty goals. NIGMS support of this training is essential in providing the environment that will allow these future physician-scientist leaders to flourish.