Developmental Psychopathology of Restrictive and Binge Eating in Childhood

儿童时期限制性饮食和暴饮暴食的发展精神病理学

基本信息

项目摘要

DESCRIPTION (provided by applicant): Candidate: I am a Research Assistant Professor with the Eating Disorders Program in the Department of Psychiatry at The University of North Carolina at Chapel Hill. I have training in developmental psychopathology and eating disorders. I am seeking training in childhood deregulated eating, psychiatric genetics, longitudinal data analysis, and proteome methodology. Career Goals: My ultimate goal is to define prodromal eating disorders-early signs and symptoms that emerge before the onset of eating disorders-and develop a prognostic algorithm of eating disorder risk in children. Translational science to detect prodromal eating disorders could have the potential to prevent later eating disorders by altering developmental trajectories through early intervention. Career Development: I plan to build my skills and expertise in four areas: 1. Dysregulated eating in childhood; 2. Psychiatric genetics including the development of a polygenic risk index; 3. Longitudinal data analyses including latent trajectory modeling; and 4. Prodrome theory, methodology, and collaborative research. Research Project: The proposed project leverages existing resources by using previously collected data from the Norwegian Mother and Child Study (MoBa), a longitudinal prospective birth cohort study and biobank of ~110,000 Norwegian children and their mothers. First, I will map the developmental trajectories of restrictive eating in children from 18 months t 8 years of age and test models of pathways to 8-year-old's restrictive eating (e.g. food avoidance and emotional underrating eating less when angry or anxious). Second, I will map the developmental trajectories of binge eating in children from 36 months to 8 years of age and test models of pathways to 8-year-old's binge eating (e.g. eating large amount of food in a short period of time and experiencing loss of control over eating having the impression that one could not stop eating). Third, I will examine the impact of the addition of an anorexia nervosa polygenic risk index to inform trajectory and pathway models of children's restrictive eating in the children of mothers with and without anorexia nervosa. In future independent applications (R01s), these results will inform multi-method direct observations of the children at risk for eating disorders in MoBa as they age into adolescence, the period of greatest risk for eating disorder onset. Environment: The research and training will take place in the Department of Psychiatry at UNC Chapel Hill with additional training in the Norwegian Institute of Public Health. Mentorship: The mentorship team includes lead mentor, Dr. Cynthia Bulik, a psychologist, and internationally recognized expert in eating disorder research and treatment and co-mentor, Dr. Patrick Sullivan, a psychiatrist and leading expert in psychiatric genetics. Dr. Eliana Perrin, consultant, is a pediatrician with expertise in deregulated eating in middle childhood. Dr. Kari North, consultant, is a genetic epidemiologist and will provide expertise in integrating genetics and longitudinal data analysis and methods. Dr. Ted Reichborn-Kjennerud, consultant, is a psychiatrist and expert in the MoBa dataset and psychiatric genetic epidemiology. Dr. Robert Hamer, a consultant, is a biostatistician and expert in longitudinal modeling. Dr. Diana Perkins, consultant, is a psychiatrist and co-principal investigator of genomics component of the North American Prodrome Longitudinal Study for schizophrenia.
描述(由申请人提供): 候选人:我是北卡罗来纳大学教堂山分校精神病学系饮食失调项目的研究助理教授。我接受过发展精神病理学和饮食失调方面的培训。我正在寻求有关儿童放松饮食管制、精神遗传学、纵向数据分析和蛋白质组方法的培训。职业目标:我的最终目标是定义前驱饮食失调(饮食失调发作前出现的早期体征和症状)并开发儿童饮食失调风险的预后算法。检测前驱饮食失调的转化科学有可能通过早期干预改变发育轨迹来预防后来的饮食失调。职业发展:我计划在四个领域培养我的技能和专业知识: 1. 童年时期饮食失调; 2. 精神遗传学,包括制定多基因风险指数; 3. 纵向数据分析,包括潜在轨迹建模; 4.前驱症状理论、方法和合作研究。研究项目:拟议项目通过使用先前从挪威母亲和儿童研究 (MoBa) 收集的数据来利用现有资源,MoBa 是一项纵向前瞻性出生队列研究和约 110,000 名挪威儿童及其母亲的生物库。首先,我将绘制 18 个月至 8 岁儿童限制性饮食的发展轨迹,并测试 8 岁儿童限制性饮食的路径模型(例如避免食物和情绪低估愤怒或焦虑时少食)。其次,我将绘制36个月至8岁儿童暴食的发展轨迹,并测试8岁儿童暴食的路径模型(例如短时间内吃大量食物,并经历对饮食失去控制,产生无法停止进食的印象)。第三,我将研究添加神经性厌食症多基因风险指数的影响,以了解患有和不患有神经性厌食症的母亲的孩子的儿童限制性饮食的轨迹和途径模型。在未来的独立应用(R01)中,这些结果将为 MoBa 中患有饮食失调风险的儿童在青春期(饮食失调发病风险最大的时期)的多方法直接观察提供信息。环境:研究和培训将在北卡罗来纳大学教堂山分校精神病学系进行,并在挪威公共卫生研究所进行额外培训。导师:导师团队包括首席导师 Cynthia Bulik 博士(心理学家)和国际公认的饮食失调研究和治疗专家,以及共同导师 Patrick Sullivan 博士(精神病学家和精神病遗传学领先专家)。博士。 Eliana Perrin 是一位儿科医生,顾问,在解除儿童中期饮食管制方面拥有丰富的专业知识。顾问卡里·诺斯 (Kari North) 博士是一位遗传流行病学家,将提供整合遗传学和纵向数据分析和方法方面的专业知识。顾问 Ted Reichborn-Kjennerud 博士是一位精神病学家,也是 MoBa 数据集和精神病遗传流行病学方面的专家。顾问罗伯特·哈默博士是一位生物统计学家和纵向建模专家。戴安娜·珀金斯 (Diana Perkins) 博士是一名顾问,是一名精神病学家,也是北美精神分裂症前驱症状纵向研究基因组学部分的联合首席研究员。

项目成果

期刊论文数量(6)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Facebook Use and Disordered Eating in College-Aged Women.
Perfectionism Group Treatment for Eating Disorders in an Inpatient, Partial Hospitalization, and Outpatient Setting.
The incidence of eating disorders in a Danish register study: Associations with suicide risk and mortality.
丹麦登记研究中饮食失调的发生率:与自杀风险和死亡率的关联。
  • DOI:
    10.1016/j.jpsychires.2015.03.003
  • 发表时间:
    2015
  • 期刊:
  • 影响因子:
    4.8
  • 作者:
    Zerwas,Stephanie;Larsen,JanneTidselbak;Petersen,Liselotte;Thornton,LauraM;Mortensen,PrebenBo;Bulik,CynthiaM
  • 通讯作者:
    Bulik,CynthiaM
Obstetric and gynecologic problems associated with eating disorders.
{{ item.title }}
{{ item.translation_title }}
  • DOI:
    {{ item.doi }}
  • 发表时间:
    {{ item.publish_year }}
  • 期刊:
  • 影响因子:
    {{ item.factor }}
  • 作者:
    {{ item.authors }}
  • 通讯作者:
    {{ item.author }}

数据更新时间:{{ journalArticles.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ monograph.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ sciAawards.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ conferencePapers.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ patent.updateTime }}

Stephanie Christine Zerwas其他文献

Stephanie Christine Zerwas的其他文献

{{ item.title }}
{{ item.translation_title }}
  • DOI:
    {{ item.doi }}
  • 发表时间:
    {{ item.publish_year }}
  • 期刊:
  • 影响因子:
    {{ item.factor }}
  • 作者:
    {{ item.authors }}
  • 通讯作者:
    {{ item.author }}

{{ truncateString('Stephanie Christine Zerwas', 18)}}的其他基金

Developmental Psychopathology of Restrictive and Binge Eating in Childhood
儿童时期限制性饮食和暴饮暴食的发展精神病理学
  • 批准号:
    8706973
  • 财政年份:
    2013
  • 资助金额:
    $ 16.27万
  • 项目类别:
Developmental Psychopathology of Restrictive and Binge Eating in Childhood
儿童时期限制性饮食和暴饮暴食的发展精神病理学
  • 批准号:
    8487604
  • 财政年份:
    2013
  • 资助金额:
    $ 16.27万
  • 项目类别:

相似海外基金

Essential Fatty Acid Deficiency as a modifiable determinant of cognitive dysfunction among 6-18-year-old Ugandan children of varying perinatal HIV status
必需脂肪酸缺乏是不同围产期 HIV 状况的 6-18 岁乌干达儿童认知功能障碍的可改变决定因素
  • 批准号:
    10741470
  • 财政年份:
    2022
  • 资助金额:
    $ 16.27万
  • 项目类别:
A study of student discipline under the 18-year-old adults: From the perspective of student participation in the disciplinary process
18岁成年人下的学生纪律研究——基于学生参与纪律过程的视角
  • 批准号:
    22K02260
  • 财政年份:
    2022
  • 资助金额:
    $ 16.27万
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
A research on systematic and comprehensive curriculum for social studies and civics aimed at cultivating the ability of 18-year-old citizens
以培养18岁公民能力为目标的系统综合社会学与公民课程研究
  • 批准号:
    20H01670
  • 财政年份:
    2020
  • 资助金额:
    $ 16.27万
  • 项目类别:
    Grant-in-Aid for Scientific Research (B)
Refurbishment of a 18-Year Old PECVD System
翻新已有 18 年历史的 PECVD 系统
  • 批准号:
    RTI-2021-00270
  • 财政年份:
    2020
  • 资助金额:
    $ 16.27万
  • 项目类别:
    Research Tools and Instruments
Building systems for education and consultation about prevention and assistance for consumer troubles by 18-year-old adult high-school students
构建18岁成人高中生消费纠纷预防和救助教育和咨询体系
  • 批准号:
    20K13799
  • 财政年份:
    2020
  • 资助金额:
    $ 16.27万
  • 项目类别:
    Grant-in-Aid for Early-Career Scientists
A Study of Civics Curriculum Development which Clarify the Qualities and Abilities aimed to be 18-Year-Old Adult
明确18岁成人素质和能力的公民课程开发研究
  • 批准号:
    17K04908
  • 财政年份:
    2017
  • 资助金额:
    $ 16.27万
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
18-year-old female and male students´ conceptions of death: The influence of the film viewing
18岁男女学生的死亡观:电影观看的影响
  • 批准号:
    5358087
  • 财政年份:
    2002
  • 资助金额:
    $ 16.27万
  • 项目类别:
    Research Grants
What will remain? Traces of school literature instructions in the use of media and personel reading history of 17/18-year-old graduates of the "Hauptschule"
剩下什么?
  • 批准号:
    5263408
  • 财政年份:
    2000
  • 资助金额:
    $ 16.27万
  • 项目类别:
    Priority Programmes
{{ showInfoDetail.title }}

作者:{{ showInfoDetail.author }}

知道了