Adenosine and the Basal Forebrain in the Control of Behavioral State

腺苷和基底前脑控制行为状态

• 批准号: 7786264
• 负责人: ROBERT E STRECKER
• 金额: --
• 依托单位: VA BOSTON HEALTH CARE SYSTEM
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-04-01 至 2013-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7786264
• 关键词: Adenocarcinoma Cell; Adenosine; Adenosine A1 Receptor; Affect; Agar; Animal Model; Apoptosis; Attention; Award; Basic Science; Behavior Control; Behavioral; Behavioral Symptoms; Binding; Biological; Biological Assay; Brain; Cardiovascular system; Caring; Cell Cycle; Cell Death; Cell Proliferation; Cessation of life; Chronic; Clinical Data; Clinical Research; Clinical Trials; Cognition; Cognitive; Coupled; Data; Development; Emergency Situation; Endocrine; Epigenetic Process; Erinaceidae; Event; Excessive Daytime Sleepiness; FDA approved; Feedback; Flow Cytometry; Generations; Genetic; Goals; Grant; Growth; Health; Healthcare; Healthcare Systems; Heart Diseases; Hippocampus (Brain); Histones; Histopathology; Human; Hygiene; Image; Immune; Impaired cognition; Intervention; Investigation; Knowledge; Laboratories; Lead; Learning; Life; Long-Term Potentiation; Malignant Neoplasms; Malignant neoplasm of pancreas; Mammals; Measures; Mediating; Mediator of activation protein; Medical; Memory; Memory impairment; Mental disorders; Messenger RNA; Microscopic; Military Personnel; Modeling; Molecular; Molecular Genetics; Motion; Mus; Names; Narcolepsy; Neurobiology; Neuromodulator; Neurons; Neurosciences; Occupational; Pancreas; Pancreatic Adenocarcinoma; Pathway interactions; Patients; Pattern; Performance; Pharmaceutical Preparations; Physiological; Population; Post-Traumatic Stress Disorders; Prevalence; Procedures; Purinergic P1 Receptors; Quality of life; RNA; Rattus; Recovery; Regimen; Relative (related person); Reporting; Research; Research Personnel; Residencies; Resistance; Role; Safety; Shapes; Signal Transduction; Sleep; Sleep Apnea Syndromes; Sleep Disorders; Sleep disturbances; Sleeplessness; Societies; Sonic Hedgehog Pathway; Stress; Symptoms; Synaptic plasticity; Testing; Therapeutic; Toxic effect; Training; Transportation; Traumatic Brain Injury; Treatment Efficacy; Veterans; Vorinostat; Wakefulness; Water; Work; Xenograft procedure; alertness; basal forebrain; base; cancer cell; chemotherapeutic agent; chronic pain; density; design; drug testing; extracellular; human SMO protein; improved; in vivo; inhibitor/antagonist; innovation; male; neurophysiology; novel; novel strategies; pancreatic cancer cells; pancreatic neoplasm; pre-clinical; protein function; public health relevance; receptor; relating to nervous system; research study; resistance mechanism; response; sleep onset; smoothened signaling pathway; social; success; therapy development; tumor; tumor growth; vigilance