The 13th International Workshop on Developmental Nephrology: From Basic Models to Translational Science

第十三届发育肾病学国际研讨会：从基础模型到转化科学

• 批准号: 8908658
• 负责人: CARLTON MATTHEW BATES
• 金额: $ 1万
• 依托单位: UNIVERSITY OF PITTSBURGH AT PITTSBURGH
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-04-01 至 2016-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8908658
• 关键词: Accounting; Adult; American; Award; Basic Science; Biology; Cellular biology; Child; Childhood; Chronic Kidney Failure; Clinical; Congenital Abnormality; Coupled; Development; Developmental Biology; Dialysis procedure; Discipline; Disease; Educational workshop; Faculty; Fees; Fostering; Foundations; Funding; Genetic; Goals; Grant; Health; Human; International; Kidney; Kidney Failure; Kidney Transplantation; Knowledge; Laboratories; Life; Longevity; Lower urinary tract; Medical; Medicine; Modeling; Molecular Biology; Morbidity - disease rate; Natural regeneration; Nephrology; Participant; Pathology; Patient Care; Patients; Physiology; Postdoctoral Fellow; Qualifying; Regenerative Medicine; Research Personnel; Science; Scientist; Societies; Stem cells; Techniques; Therapeutic; Therapeutic Studies; Training Programs; Translational Research; Travel; Underrepresented Minority; United States; Urinary tract; Urology; Woman; Work; abstracting; career; congenital anomaly; cost; meetings; neonatal care; programs; public health relevance; regenerative therapy; repaired; stem cell biology; symposium

 DESCRIPTION (provided by applicant): Congenital anomalies of the kidney and urinary tract account for the majority of cases of renal failure in the first year of life. Despite progress in therapies for chronic kidney disease, the average lifespan for children on dialysis and after kidney transplantation is shortened by 50 years and 25 years, respectively. These pressing clinical issues coupled with recent advances in the developmental sciences necessitate defining the mechanisms involved in kidney and urinary tract development. Furthermore, the basic and translational research presented at the 13th International Developmental Nephrology Workshop will form the foundation for developing regenerative therapies for children and adults with irreversible kidney damage. The primary goal of the Workshop is to provide a comprehensive, state-of-the-art meeting on the developing kidney and urinary tract. A secondary goal is to bring together basic and clinician-scientists to foster cross-collaborative science. A third goal is to entice junior investigators (MDs and PhDs), women, and under-represented minorities into careers focused on kidney and urinary tract development and disease. Thus, the participants include a diverse spectrum of investigators in a forum conducive to the exchange of new knowledge, techniques, and concepts relating to the biology, physiology, genetics and therapeutic approaches for the developing kidney and urinary tract in health and disease. Workshop participants include investigators in the disciplines of pediatric nephrology, renal medicine, urology, physiology, cell biology, developmental biology, stem cell biology, pathology, and molecular biology, and regenerative medicine. As in the past, the program will also include internationally recognized leaders in developmental biology whose work is not centered on the kidney. The meeting format and the outstanding slate of speakers assembled for the Workshop will provide a unique educational opportunity for qualified junior faculty and senior post-doctoral fellows. Not only will they be exposed to cutting edge science, but the Workshop is conducive to small group discussions and interactions that should spark new collaborative interactions among participants. This meeting is unique in being entirely dedicated to developmental nephrology. There is no other regularly occurring meeting dedicated to this subject. Other larger annual meetings with some overlap (such as the American Society of Nephrology) do not replicate the focus, the smaller venue and the breadth of speakers and participants of the IWDN meeting. The aim of this proposal is to seek support for travel awards for up to 10 young investigators to attend this conference, to partially defray the conference fees (including registration, meals, lodging, and shuttle costs to and from the airport). The funds will be used to support young investigators and trainees from laboratories and training programs in the United States that have submitted abstracts to attend the meeting. A subcommittee of the Workshop Organizing Committee will review the abstract submissions and CVs and select the most meritorious applicants for these awards, with special emphasis on women and underserved minorities.

 描述（由申请人提供）：先天性肾脏和泌尿道异常占出生后第一年肾衰竭病例的大多数。尽管慢性肾脏疾病的治疗取得了进展，但接受透析和肾移植的儿童的平均寿命分别缩短了50年和25年。这些紧迫的临床问题，再加上最近在发展科学的进展，有必要确定参与肾脏和尿路发育的机制。此外，在第13届国际发育肾脏学研讨会上提出的基础和转化研究将为患有不可逆肾损伤的儿童和成人开发再生疗法奠定基础。该研讨会的主要目标是提供一个全面的，国家的最先进的会议上发展的肾脏和泌尿道。第二个目标是将基础科学家和临床科学家聚集在一起，以促进交叉协作科学。第三个目标是吸引初级研究人员（医学博士和博士），女性和代表性不足的少数民族进入专注于肾脏和泌尿道发育和疾病的职业生涯。因此，与会者包括不同领域的研究人员在一个论坛，有利于交流新的知识，技术和概念有关的生物学，生理学，遗传学和治疗方法的发展中的肾脏和泌尿道的健康和疾病。研讨会的参与者包括儿科肾脏病学，肾脏医学，泌尿学，生理学，细胞生物学，发育生物学，干细胞生物学，病理学，分子生物学和再生医学学科的研究人员。与过去一样，该计划还将包括国际公认的发育生物学领导者，他们的工作不以肾脏为中心。会议的形式和杰出的发言者名单组装的讲习班将提供一个独特的教育机会，合格的初级教师和高级博士后 伙计们他们不仅将接触到尖端科学，而且研讨会有利于小组讨论和互动，这将激发参与者之间新的合作互动。这次会议的独特之处在于完全致力于发展肾病学。没有其他定期举行的会议专门讨论这一问题。其他一些重叠的大型年会（如美国肾脏病学会）没有复制IWDN会议的重点，较小的场地和演讲者和参与者的广度。本提案的目的是寻求对最多10名年轻调查员参加这次会议的旅费补助的支持，以支付部分会议费用（包括登记、膳食、住宿和往返机场的班车费用）。这笔资金将用于 支持来自美国实验室和培训项目的年轻研究人员和受训人员参加会议。讲习班组织委员会的一个小组委员会将审查提交的摘要和简历，并为这些奖项挑选最有价值的申请人，特别强调妇女和服务不足的少数民族。