Omics Core
Omics Core
批准号:
8978011
负责人:
Xiang Zhang
金额:
$46.09万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2016
资助国家:
美国
项目状态:
已结题
起止时间:
2016-05-15 至 2021-04-30
关键词:
AcidsAcroleinAffinityAlcohol NutritionAlcoholic Liver DiseasesAlcoholsAnimalsAttentionAttenuatedAutomobile DrivingBioinformaticsBiologicalBiotinBloodBlood specimenBody WeightCell LineCellsChronicComplex MixturesCurcuminDataData CollectionData ReportingData SetDevelopmentDrug InteractionsEmbryoEndotoxemiaEnsureEnvironmentEpigenetic ProcessExtracellular MatrixFecesFibroblastsGas ChromatographyGingerGoalsGrapefruitHepaticHigh Pressure Liquid ChromatographyHistone AcetylationHistonesHuman ResourcesInflammationInjuryInstitutionInterleukin-2IntestinesLactobacillus casei rhamnosusLiquid substanceLiverLiver DysfunctionLiver diseasesLungLysineMass Spectrum AnalysisMeasuresMediatingMetabolicMethodologyMethodsMolecularMolecular EvolutionMusNeural Crest CellOrganPatternPeptidesPerformancePost-Translational Protein ProcessingPreparationProtein AnalysisProtein FragmentProteinsProteomicsProtocols documentationResearchResearch InfrastructureResearch PersonnelResolutionResourcesRoleSamplingScienceSerumServicesStandardizationSulforaphaneTNFRSF5 geneTechniquesTechnologyTimeTissue SampleTissuesTraining and EducationTranscriptional RegulationUnsaturated FatsUrineabstractingadductalcohol effectdata sharingdesignexosomehistone methylationhistone modificationinstrumentliquid chromatography mass spectrometryliver injurylong chain fatty acidmalemeetingsmembermetabolomicsmethod developmentmultiple reaction monitoringnanoparticlenovelnutritionphosphoproteomicsprogramsprotein metaboliteresponsesample collectionsaturated fatsuccesstoxicanttributyrintwo-dimensional
中文摘要
文摘:
英文摘要
Abstract:
The primary function of Omics Core is to provide members of the ULARC with the expertise, resources and
facilities needed for metabolomic, proteomic and bioinformatic analyses of biological samples collected to
study liver injury, nutrition, gut:liver interactions, and liver:environment/toxicant/drug interactions. OMICS Core
personnel will assist with the design of sample collection protocols, will drive the development and the
execution of novel and robust chromatographic methods for sample separation and mass spectrometric
methods for the analysis of proteins, peptides, and metabolites with a goal of providing a greater
understanding of the evolution of molecular mechanisms that correlate with or participate in liver dysfunction.
The core will ensure uniformity and standardization in sample preparation, method development, instrument
performance, data collection, data reporting and data sharing. The Core endeavors to contribute to the overall
success and utility of the ULARC and to enhance the infrastructure and the technical and academic capabilities
of the institution as a whole. In addition to its function as a service core, we will also promote the education and
training of the ULARC members with regards to state-of–the-art Omics and Bioinformatics methods; with
particular attention to the ULARC junior investigators.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Mechanistic and therapeutic investigation of secondary metastatic seeding from breast cancer bone lesion
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批准号:10650756
-
项目类别:
-
资助金额:$47.62万
-
财政年份:2020
-
负责人:Xiang Zhang
-
依托单位:
Mechanistic and therapeutic investigation of secondary metastatic seeding from breast cancer bone lesion
-
批准号:10028080
-
项目类别:
-
资助金额:$50.09万
-
财政年份:2020
-
负责人:Xiang Zhang
-
依托单位:
Mechanistic and therapeutic investigation of secondary metastatic seeding from breast cancer bone lesion
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批准号:10204993
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项目类别:
-
资助金额:$48.59万
-
财政年份:2020
-
负责人:Xiang Zhang
-
依托单位:
Unveiling the mechanisms underlying secondary metastasis and possible therapeutic windows
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批准号:10818995
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项目类别:
-
资助金额:$7.54万
-
财政年份:2020
-
负责人:Xiang Zhang
-
依托单位:
Omics Core
-
批准号:10026252
-
项目类别:
-
资助金额:$31.42万
-
财政年份:2016
-
负责人:Xiang Zhang
-
依托单位:
Omics Core
-
批准号:10608169
-
项目类别:
-
资助金额:$29.85万
-
财政年份:2016
-
负责人:Xiang Zhang
-
依托单位:
Omics Core
-
批准号:10625861
-
项目类别:
-
资助金额:$38.04万
-
财政年份:2016
-
负责人:Xiang Zhang
-
依托单位:
Omics Core
-
批准号:10056417
-
项目类别:
-
资助金额:$33.04万
-
财政年份:2016
-
负责人:Xiang Zhang
-
依托单位:
OMICS CORE
-
批准号:8813877
-
项目类别:
-
资助金额:$34.63万
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财政年份:2016
-
负责人:Xiang Zhang
-
依托单位:
Omics Core
-
批准号:10377893
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项目类别:
-
资助金额:$31.44万
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财政年份:2016
-
负责人:Xiang Zhang
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依托单位:
Ultra Performance Liquid Chromatography High Resolution High Mass Accuracy Mass Spectrometer
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批准号:8826389
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项目类别:
-
资助金额:$60.0万
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财政年份:2015
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负责人:Xiang Zhang
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依托单位:
Translational Research in Breast Cancer
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批准号:10460204
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项目类别:
-
资助金额:$209.15万
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财政年份:2014
-
负责人:Xiang Zhang
-
依托单位:
Osteoclast-independent mechanisms of early-stage bone colonization of breast canc
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批准号:9118111
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项目类别:
-
资助金额:$32.47万
-
财政年份:2014
-
负责人:Xiang Zhang
-
依托单位:
Osteoclast-independent mechanisms of early-stage bone colonization of breast canc
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批准号:9330803
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项目类别:
-
资助金额:$32.47万
-
财政年份:2014
-
负责人:Xiang Zhang
-
依托单位:
Osteoclast-Independent Mechanisms of Early-Stage Bone Colonization of Breast Cancer
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批准号:10369640
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项目类别:
-
资助金额:$37.24万
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财政年份:2014
-
负责人:Xiang Zhang
-
依托单位:
Osteoclast-independent mechanisms of early-stage bone colonization of breast canc
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批准号:8910672
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项目类别:
-
资助金额:$32.47万
-
财政年份:2014
-
负责人:Xiang Zhang
-
依托单位:
Osteoclast-independent mechanisms of early-stage bone colonization of breast canc
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批准号:8670428
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项目类别:
-
资助金额:$32.47万
-
财政年份:2014
-
负责人:Xiang Zhang
-
依托单位:
Translational Research in Breast Cancer
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批准号:10704510
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项目类别:
-
资助金额:$197.44万
-
财政年份:2014
-
负责人:Xiang Zhang
-
依托单位:
Translational Research in Breast Cancer
-
批准号:10219965
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项目类别:
-
资助金额:$209.28万
-
财政年份:2014
-
负责人:Xiang Zhang
-
依托单位:
Osteoclast-Independent Mechanisms of Early-Stage Bone Colonization of Breast Cancer
-
批准号:10602492
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项目类别:
-
资助金额:$37.24万
-
财政年份:2014
-
负责人:Xiang Zhang
-
依托单位:
国内基金
海外基金
Acrolein调控耳蜗核神经元-胶质细胞网络参与感音神经性耳聋发病机制的研究
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批准号:81570922
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项目类别:面上项目
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资助金额:65.0万元
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批准年份:2015
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负责人:屈涓
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依托单位:
acrolein在脊髓损伤后慢性疼痛发生发展中的作用及机制研究
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批准号:81171052
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项目类别:面上项目
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资助金额:60.0万元
-
批准年份:2011
-
负责人:武胜昔
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依托单位: