Northwestern University Clinical & Translational Sciences Institute (NUCATS) 2.0

描述(由申请人提供)： 我们迅速将新的科学知识转化为改善患者和人群健康的能力仍然受到众多挑战的限制。西北大学临床与翻译科学研究所(NUCATS)成立于2007年，旨在为西北大学及其他地方的临床与翻译(C&T)科学提供支持。西北大学(NU)是一所领先的国家研究型大学，附属于全国知名的临床合作伙伴。NUCATS是全国公认的C&T科学几个关键领域的创新领导者，在临床前治疗开发、健康和生物医学信息学系统、研究网络平台和培训计划等领域开创了新颖和可扩展的方法，以促进多学科团队科学；并创建和领导了芝加哥地区三个CTSA的地区性联盟，以促进社区参与活动和基于实践的研究。在本提案中，我们描述了我们的第二代研究所-NUCATS 2.0。NUCATS 2.0的使命是“加速患者和人群的变革性研究发现”。我们的愿景是通过追求三个全球目标，将NUCATS转变为高度整合的学术联系的国家模式，不断提高创新C&T研究的质量、安全、效率和速度：1)通过整合将研究人员与资源、培训、资金机会和战略合作伙伴联系在一起的流程和计划，加快翻译速度和提高效率；2)开发和实施创新系统，以识别、评估、促进和传播科学突破，并提高C&T研究的质量、安全和成本效益；3)通过团队建设、教育和培训，促进西北大学的合作、创新和翻译文化，以增强未来多学科翻译研究团队的能力。NUCATS 2.0将成为一个创新的领导者，推动拯救生命和促进健康的科学发现的快速转化，以改善临床实践和人口健康。

DESCRIPTION (provided by applicant): Our ability to translate new scientific knowledge rapidly into improvements in patient and population health continues to be limited by numerous challenges. The Northwestern University Clinical and Translational Sciences Institute (NUCATS) was launched in 2007 to create a home supporting clinical and translational (C&T) science at Northwestern and beyond. Northwestern University (NU) is a leading national research university affiliated with nationally-renowned clinical partners. NUCATS is nationally recognized as an innovation leader in several key areas of C&T science, pioneering novel and scalable approaches in the areas of preclinical therapeutic development, health and biomedical informatics systems, research networking platforms and training programs to promote multi-disciplinary team science; and creation and leadership of a regional consortium of the three Chicago-area CTSAs to promote community engagement activities and practice-based research. In the present proposal, we describe our second generation institute, NUCATS 2.0. The Mission of NUCATS 2.0 is "Speeding transformative research discoveries to patients and the population." Our Vision is to transform NUCATS into a national model of a highly integrated academic nexus that continually increases the quality, safety, efficiency and speed of innovative C&T research, by pursuing three Global Aims: 1) To speed translation and improve efficiency by integrating processes and programs that connect researchers with a continuum of resources, training, funding opportunities, and strategic partners; 2) To develop and implement innovative systems to identify, evaluate, facilitate and disseminate scientific breakthroughs, and improve the quality, safety and cost-effectiveness of C&T research; and 3) To promote Northwestern's culture of collaboration, innovation and translation through team-building, education, and training to empower the multi-disciplinary translational research teams of tomorrow. NUCATS 2.0 will be an innovative leader driving the rapid translation of life-saving and health promoting scientific discoveries to improv clinical practice and population health.