E-Cigarette Use and Longitudinal Changes in Cigarette Smoking and Health

电子烟的使用以及吸烟与健康的纵向变化

基本信息

批准号：
9077678
负责人：
SEAN ESTEBAN MCCABE
金额：
$ 21.74万
依托单位：
UNIVERSITY OF MICHIGAN AT ANN ARBOR
依托单位国家：
美国
项目类别：
财政年份：
2016
资助国家：
美国
起止时间：
2016-09-01 至 2019-08-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9077678
关键词：
18 year old 21 year old Accounting Address Adolescence Adolescent Age Age of Onset Alcohol or Other Drugs use Behavior Cause of Death Cessation of life Characteristics Cigarette Cigarette Smoker Data Data Analyses Development Disease Drug abuse Electronic cigarette Enrollment Epidemiology Ethnic Origin Exposure to Frequencies Future Gender Health Health Policy Health behavior High Prevalence High School Student Knowledge Lead Long-Term Effects Longitudinal Studies Measures Monitor Natural History Nicotine Outcome Pattern Prevalence Prevention Preventive Intervention Public Health Race Recording of previous events Research Risk Risk Factors Sample Size Sampling School-Age Population Secondary Schools Services Smoke Smoking Socioeconomic Status Students Subgroup Surveys Testing Time Tobacco use Weight Youth adolescent smoking age group base cigarette smoking clinical practice cohort disability high school improved public health relevance rate of change sex smoking cessation tenth grade twelfth grade young adult

项目摘要

DESCRIPTION (provided by applicant): This project, entitled "E-Cigarette Use and Longitudinal Changes in Cigarette Smoking and Health" proposes to use three waves of nationally representative longitudinal data to examine the relationships among e-cigarette use, traditional cigarette smoking, other tobacco use, other substance use behaviors and health problems from adolescence to young adulthood. E-cigarette use has increased significantly between 2011 and 2014 among U.S. adolescents and has surpassed the current use of traditional cigarette smoking among adolescents. In 2014, more than one in every six U.S. high school seniors used e- cigarettes in the past month. Never-smoking adolescents who have used e-cigarettes are twice more likely to say they intend to smoke traditional cigarettes than never-smoking youth who have not used e-cigarettes. Traditional cigarette smoking is most prevalent among young adults following high school (ages 18-24) relative to all other age groups. Tobacco use remains the leading preventable cause of death, and traditional cigarette smoking is responsible for more than 480,000 deaths per year in the U.S. This raises important public health questions regarding the long-term effects of e-cigarette use: 1) Does e-cigarette use change the risk for subsequent traditional cigarette smoking, other tobacco use, and health problems? 2) Are traditional cigarette smokers more likely to quit smoking after initiating e-cigarette use? To date, the long-term patterns and consequences associated with e-cigarette use in nationally representative samples of adolescents have not been studied. To address these gaps in knowledge, we will conduct a secondary analysis of data from the Monitoring the Future (MTF) study, a multi-cohort epidemiological survey of a sample of approximately 142,500 students enrolled in U.S. private/public secondary schools. The MTF study also features a longitudinal panel sample of high school seniors (modal age: 18 years) who were followed 1-2 years (modal ages: 19-20 years) and 3-4 years (modal ages: 21-22 years) after high school, resulting in three waves of longitudinal data. Several new questions were recently added to the MTF study to assess e-cigarette use. As a result, the MTF has sufficient measures and sample size to test for potential gender, race/ethnicity, and socioeconomic status differences in e-cigarette use and its consequences. Our study aims to: (1) estimate the bias in estimated rates of e-cigarette use and traditional cigarette smoking in adolescence and young adulthood and estimated rates of change over time in e-cigarette use and traditional cigarette smoking due to differential attrition in the MTF study, by comparing and evaluating alternative weighting and imputation approaches; (2) examine the trajectories of e-cigarette use, traditional cigarette smoking, other tobacco use, other substance use behaviors, and health problems from adolescence to young adulthood as a function of e-cigarette use history at age 18; and (3) assess the effects of age of onset and frequency of e-cigarette use on the trajectories of traditional cigarette smoking, other tobacco use, other substance use behaviors, and health problems.

描述（由适用提供）：该项目的标题为“使用电子烟和吸烟和健康的纵向变化”建议使用三波全国代表性的纵向数据浪潮，以研究使用电子烟的使用，传统的吸烟，其他烟草使用，其他毒品的使用行为，其他烟草的使用行为，以及来自青少年的年轻人的健康问题。在2011年至2014年之间，在美国青少年中，电子烟的使用量显着增加，并且在青少年中使用传统香烟吸烟的目前使用。在2014年，过去一个月，美国六位高中生中每六个以上使用电子烟。使用电子烟的青少年从未吸烟的青少年说，他们打算吸烟的可能性要比从未吸烟的青年来吸烟的可能性要高两倍。相对于所有其他年龄段，高中毕业后的年轻人（18-24岁），传统的香烟吸烟最为普遍。烟草使用仍然是可预防的死亡原因，传统的香烟吸烟造成美国每年超过480,000人死亡，这引发了有关电子烟的长期影响使用的重要公共健康问题：1）电子烟的使用会改变随后的传统吸烟，其他烟草使用，其他烟草使用的风险吗？ 2）传统的吸烟者在使用电子烟后是否更有可能戒烟？迄今为止，尚未研究与在国家代表性的青少年样本中使用电子烟相关的长期模式和后果。为了解决这些知识的差距，我们将对监测未来（MTF）研究的数据进行二次分析，该研究是一项多核心流行病学调查，对大约142,500名学生入学的学生的样本进行了研究。 MTF的研究还包括一个高中生（模态年龄：18岁）的纵向面板样本，他们在高中后进行了1-2岁（模态年龄：19-20岁）和3-4岁（模态年龄：21-22岁），导致了三波纵向数据。最近将几个新问题添加到MTF研究中，以评估电子烟的使用。结果，MTF具有足够的措施和样本量来测试潜在的性别，种族/种族以及电子烟使用及其后果的社会经济状况差异。我们的研究旨在：（1）估计青少年和成年期电子烟的使用率和传统的香烟吸烟的偏差，以及通过比较和评估交替的权重和浮标的方法，由于MTF研究中的电子烟的使用和传统的香烟吸烟而在电子烟使用和传统的香烟吸烟中随着时间的推移而估计的变化率；（2）检查电子烟的使用轨迹，传统的香烟吸烟，其他烟草使用，其他药物使用行为以及从青春期到年轻成年的健康问题，这是E-I-I-Acigarette在18岁时使用历史的函数；（3）评估使用年龄和电子烟的频率对传统香烟吸烟，其他烟草使用，其他药物使用行为和健康问题的轨迹的影响。