E-Cigarette Use and Longitudinal Changes in Cigarette Smoking and Health

电子烟的使用以及吸烟与健康的纵向变化

• 批准号: 9339655
• 负责人: SEAN ESTEBAN MCCABE
• 金额: $ 21.74万
• 依托单位: UNIVERSITY OF MICHIGAN AT ANN ARBOR
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-09-01 至 2019-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9339655
• 关键词: Address; Adolescence; Adolescent; Age; Age of Onset; Alcohol or Other Drugs use; Behavior; Cause of Death; Cessation of life; Characteristics; Cigarette; Cigarette Smoker; Data; Data Analyses; Development; Disease; Drug abuse; Electronic cigarette; Enrollment; Epidemiology; Ethnic Origin; Exposure to; Frequencies; Future; Gender; Health; Health Policy; High Prevalence; High School Student; Knowledge; Lead; Long-Term Effects; Longitudinal Studies; Measures; Methodology; Modality; Monitor; Natural History; Nicotine; Outcome; Pattern; Prevalence; Prevention; Preventive Intervention; Privatization; Public Health; Race; Recording of previous events; Research; Risk; Risk Factors; Sample Size; Sampling; School-Age Population; Secondary Schools; Smoke; Smoking; Smoking and Health Research; Socioeconomic Status; Students; Subgroup; Surveys; Testing; Time; Tobacco use; Weight; Youth; adolescent smoking; age effect; age group; base; cigarette smoking; clinical practice; cohort; disability; high school; improved; premature; public health relevance; rate of change; secondary analysis; service intervention; sex; smoking cessation; tenth grade; twelfth grade; young adult

 DESCRIPTION (provided by applicant): This project, entitled "E-Cigarette Use and Longitudinal Changes in Cigarette Smoking and Health" proposes to use three waves of nationally representative longitudinal data to examine the relationships among e-cigarette use, traditional cigarette smoking, other tobacco use, other substance use behaviors and health problems from adolescence to young adulthood. E-cigarette use has increased significantly between 2011 and 2014 among U.S. adolescents and has surpassed the current use of traditional cigarette smoking among adolescents. In 2014, more than one in every six U.S. high school seniors used e- cigarettes in the past month. Never-smoking adolescents who have used e-cigarettes are twice more likely to say they intend to smoke traditional cigarettes than never-smoking youth who have not used e-cigarettes. Traditional cigarette smoking is most prevalent among young adults following high school (ages 18-24) relative to all other age groups. Tobacco use remains the leading preventable cause of death, and traditional cigarette smoking is responsible for more than 480,000 deaths per year in the U.S. This raises important public health questions regarding the long-term effects of e-cigarette use: 1) Does e-cigarette use change the risk for subsequent traditional cigarette smoking, other tobacco use, and health problems? 2) Are traditional cigarette smokers more likely to quit smoking after initiating e-cigarette use? To date, the long-term patterns and consequences associated with e-cigarette use in nationally representative samples of adolescents have not been studied. To address these gaps in knowledge, we will conduct a secondary analysis of data from the Monitoring the Future (MTF) study, a multi-cohort epidemiological survey of a sample of approximately 142,500 students enrolled in U.S. private/public secondary schools. The MTF study also features a longitudinal panel sample of high school seniors (modal age: 18 years) who were followed 1-2 years (modal ages: 19-20 years) and 3-4 years (modal ages: 21-22 years) after high school, resulting in three waves of longitudinal data. Several new questions were recently added to the MTF study to assess e-cigarette use. As a result, the MTF has sufficient measures and sample size to test for potential gender, race/ethnicity, and socioeconomic status differences in e-cigarette use and its consequences. Our study aims to: (1) estimate the bias in estimated rates of e-cigarette use and traditional cigarette smoking in adolescence and young adulthood and estimated rates of change over time in e-cigarette use and traditional cigarette smoking due to differential attrition in the MTF study, by comparing and evaluating alternative weighting and imputation approaches; (2) examine the trajectories of e-cigarette use, traditional cigarette smoking, other tobacco use, other substance use behaviors, and health problems from adolescence to young adulthood as a function of e-cigarette use history at age 18; and (3) assess the effects of age of onset and frequency of e-cigarette use on the trajectories of traditional cigarette smoking, other tobacco use, other substance use behaviors, and health problems.

 描述(由申请者提供)：这个题为《电子烟使用与吸烟与健康的纵向变化》的项目建议使用三波具有全国代表性的纵向数据来研究电子烟使用、传统吸烟、其他烟草使用、其他物质使用行为和从青春期到青春期的健康问题之间的关系。2011年至2014年，美国青少年中电子烟的使用量大幅增加，已经超过了目前青少年中传统香烟的使用量。2014年，在过去的一个月里，每六名美国高中生中就有一人以上使用电子烟。从不吸烟的青少年使用过电子烟，表示他们打算抽传统香烟的可能性是从未使用电子烟的从不吸烟青少年的两倍。相对于所有其他年龄段，传统吸烟在高中毕业后(18-24岁)的年轻人中最为普遍。烟草使用仍然是主要的可预防的死亡原因，在美国，传统吸烟每年导致超过48万人死亡。这引发了关于电子烟长期影响的重要公共健康问题：1)电子烟的使用是否会改变随后传统吸烟、其他烟草使用和健康问题的风险？2)传统香烟吸烟者在开始使用电子烟后更有可能戒烟吗？到目前为止，在具有全国代表性的青少年样本中，与电子烟使用有关的长期模式和后果尚未得到研究。为了解决这些知识差距，我们将对监测未来(MTF)研究的数据进行二次分析，MTF研究是一项多队列流行病学调查，样本约为142,500名在美国私立/公立中学注册的学生。MTF研究还采用了高三学生(模式年龄：18岁)的纵向面板样本，他们在高中毕业后1-2年(模式年龄：19-20岁)和3-4年(模式年龄：21-22岁)进行了跟踪，产生了三波纵向数据。MTF的研究最近增加了几个新问题，以评估电子烟的使用情况。因此，MTF有足够的措施和样本量来测试电子烟使用及其后果方面的潜在性别、种族/族裔和社会经济地位差异。我们的研究旨在：(1)在MTF研究中，通过比较和评估不同的加权和归因法，估计青春期和青春期电子烟使用和传统吸烟估计比率的偏差，以及电子烟使用和传统吸烟随时间的变化率；(2)考察18岁时电子烟使用、传统吸烟、其他烟草使用、其他物质使用行为和从青春期到青春期的健康问题的轨迹；以及(3)评估开始使用电子烟的年龄和频率对传统吸烟、其他烟草使用、其他物质使用行为和健康问题的影响。