Anesthesiology & Perioperative Medicine Research Training

项目摘要 此竞争性续订申请(5T32GM086270)寻求为我们成功的T32的11-15年提供资金 大学麻醉学博士后培训和围手术期医学研究培训 华盛顿的。我们的主要目标是在切割方面提供博士后水平的深入研究培训。 与麻醉学和围手术期医学相关的生物医学的前沿(和新兴)领域。 我们前两个资助周期的学员已经在这个项目中取得了成功，产生了许多 同行评议的出版物，获得研究荣誉和奖项，获得SEED和NIH职业生涯 发展赠款资金，以及在科学会议上发表演讲。我们建议每人培训四名研究员。 年谁将花费2-3年的累积时间在系内各种实验室中的一个进行研究 麻醉学和疼痛医学或合作的基础科学和临床科室(例如， 药理学、遗传学、儿科学、精神病学)。由美国国立卫生研究院资助的26名教师提供研究机会 在培训博士后研究员方面有成功记录的导师，有不同的研究计划 从以实验室为基础的科学到翻译、临床和卫生服务研究。核心教员 研究负责人将在与麻醉学相关的六个主要研究领域帮助学员与导师配对 围手术期医学包括(按字母顺序)：1)心血管-肺生物学，2)临床 结果研究和流行病学，3)基因组科学和生物信息学，4)神经科学，5)疼痛，6) 药理学。该计划的目标是：从国家博士后培训人员中招募优秀的、多样化的博士后学员 申请者人才库；为学员提供与其研究领域相关的跨学科理论和方法； 为学员提供设计和进行高质量麻醉学研究的实用技能 围手术期医学(包括基础研究技能、理解负责任的研究行为、 传播研究成果的能力，并获得成功的资助技能和独立资助)； 并通过强有力的指导、广泛的研究机会和 跨部门协作。我们提供一个强大的教学计划，提供职业发展技能 它包括每月的研讨会，关于格兰特精神，科学写作，期刊俱乐部，以及进展中的作品。全 学员与导师一起完成个性化的学习计划，为他们的培训设定目标。实习生 进展由一个专门针对特定研究人员的审查委员会定期监测，并提供总结结论 向负责接收/聘用研究员的部门培训补助金咨询委员会报告，并 追随他们的进步。此外，一个外部科学监督委员会每年举行会议，向 培训项目方方面面的项目负责人。该计划的总体意图是开发 麻醉学和围手术期医学研究领域的新一代临床科学家领袖。

Project Summary This competitive renewal application (5T32GM086270) seeks funding for years 11-15 of our successful T32 postdoctoral training program in anesthesiology and perioperative medicine research training at the University of Washington. Our primary objective is to provide in-depth research training at the postdoctoral level in cutting edge (and emerging) areas of biomedical science related to anesthesiology and perioperative medicine. Trainees from our prior two funding cycles have demonstrated success in this program, producing numerous peer-reviewed publications, achieving research honors and awards, attaining seed and NIH career development grant funding, and presenting at scientific conferences. We propose training of four fellows per year who will spend 2-3 years cumulative time in research in one of a variety of laboratories in the Department of Anesthesiology and Pain Medicine or in collaborating basic science and clinical departments (e.g., Pharmacology, Genetics, Pediatrics, Psychiatry). Research opportunities are offered by 26 NIH-funded faculty mentors with proven records of success in the training of postdoctoral fellows, with diverse research programs ranging from laboratory-based science to translational, clinical, and health services research. Core faculty research leaders will help match trainees to mentors within six major research areas relevant to anesthesiology and perioperative medicine including (alphabetically): 1) cardiovascular-pulmonary biology, 2) clinical outcomes research & epidemiology, 3) genome sciences & bioinformatics, 4) neurosciences, 5) pain, and 6) pharmacology. Aims of the program are: to recruit outstanding diverse postdoctoral trainees from a national applicant pool; provide trainees with interdisciplinary theories and methods pertinent to their research area; provide trainees with the practical skills to design and conduct high quality research in anesthesiology and perioperative medicine (including fundamental research skills, understanding responsible conduct of research, ability to disseminate research findings, and acquire successful grantsmanship skills and independent funding); and to create a supportive environment through strong mentorship, a breadth of research opportunities, and collaboration across departments. We offer a robust didactic program to provide career development skills which includes monthly seminars in grantsmanship, scientific writing, journal club, and works in progress. All trainees completed individualized learning plans with their mentors to set goals for their training. Trainee progress is monitored regularly by an individualized fellow-specific review committee with summary findings reported to the departmental training grant advisory committee responsible for accepting/hiring fellows and following their progress. In addition, an external scientific oversight board meets yearly to offer advice to the program directors on all aspects of the training program. The overall intent of the program is to develop the next generation of clinician scientist leaders in anesthesiology and perioperative medicine research.