Anesthesiology & Perioperative Medicine Research Training

项目摘要 此竞争性续期申请（5 T32 GM 086270）旨在为我们成功的T32的第11-15年提供资金 麻醉学和围手术期医学研究培训博士后培训计划 在华盛顿。我们的主要目标是提供深入的研究培训，在博士后水平的切割 与麻醉学和围手术期医学相关的生物医学科学的边缘（和新兴）领域。 我们前两个资助周期的学员在该计划中取得了成功， 同行评议的出版物，获得研究荣誉和奖项，获得种子和NIH职业生涯 发展赠款资助，并在科学会议上发表演讲。我们建议每两年培训四名研究员， 一年谁将花费2-3年的累积时间在研究中的各种实验室之一，在该部门 麻醉学和疼痛医学或在合作的基础科学和临床部门（例如， 药理学、遗传学、儿科学、精神病学）。研究机会由26个NIH资助的教师提供 导师在博士后研究员的培训成功的证明记录，与多样化的研究计划 范围从实验室为基础的科学转化，临床和卫生服务研究。核心教师 研究领导者将在与麻醉学相关的六个主要研究领域内帮助学员与导师配对 和围手术期医学，包括（外科）：1）心血管-肺生物学，2）临床 结果研究和流行病学，3）基因组科学和生物信息学，4）神经科学，5）疼痛，和6） 药理学该计划的目的是：从全国范围内招募优秀的多元化博士后研究生 为学员提供与其研究领域相关的跨学科理论和方法; 为学员提供设计和进行高质量麻醉学研究的实践技能， 围手术期医学（包括基础研究技能，理解负责任的研究行为， 传播研究成果的能力，并获得成功的granitarian技能和独立的资金）; 并通过强有力的指导，广泛的研究机会， 跨部门合作。我们提供一个强大的教学计划，提供职业发展技能 其中包括每月的研讨会，科学写作，期刊俱乐部，和正在进行的工作。所有 学员在导师的指导下完成个性化的学习计划，为自己的培训设定目标。见习 由一个专门针对研究员的审查委员会定期监测进展情况，并提供调查结果摘要 向负责接受/雇用研究员的部门培训补助金咨询委员会报告， 随着他们的进步。此外，一个外部科学监督委员会每年举行会议， 培训计划的各个方面。该计划的总体意图是开发 麻醉学和围手术期医学研究的下一代临床科学家领导者。

Project Summary This competitive renewal application (5T32GM086270) seeks funding for years 11-15 of our successful T32 postdoctoral training program in anesthesiology and perioperative medicine research training at the University of Washington. Our primary objective is to provide in-depth research training at the postdoctoral level in cutting edge (and emerging) areas of biomedical science related to anesthesiology and perioperative medicine. Trainees from our prior two funding cycles have demonstrated success in this program, producing numerous peer-reviewed publications, achieving research honors and awards, attaining seed and NIH career development grant funding, and presenting at scientific conferences. We propose training of four fellows per year who will spend 2-3 years cumulative time in research in one of a variety of laboratories in the Department of Anesthesiology and Pain Medicine or in collaborating basic science and clinical departments (e.g., Pharmacology, Genetics, Pediatrics, Psychiatry). Research opportunities are offered by 26 NIH-funded faculty mentors with proven records of success in the training of postdoctoral fellows, with diverse research programs ranging from laboratory-based science to translational, clinical, and health services research. Core faculty research leaders will help match trainees to mentors within six major research areas relevant to anesthesiology and perioperative medicine including (alphabetically): 1) cardiovascular-pulmonary biology, 2) clinical outcomes research & epidemiology, 3) genome sciences & bioinformatics, 4) neurosciences, 5) pain, and 6) pharmacology. Aims of the program are: to recruit outstanding diverse postdoctoral trainees from a national applicant pool; provide trainees with interdisciplinary theories and methods pertinent to their research area; provide trainees with the practical skills to design and conduct high quality research in anesthesiology and perioperative medicine (including fundamental research skills, understanding responsible conduct of research, ability to disseminate research findings, and acquire successful grantsmanship skills and independent funding); and to create a supportive environment through strong mentorship, a breadth of research opportunities, and collaboration across departments. We offer a robust didactic program to provide career development skills which includes monthly seminars in grantsmanship, scientific writing, journal club, and works in progress. All trainees completed individualized learning plans with their mentors to set goals for their training. Trainee progress is monitored regularly by an individualized fellow-specific review committee with summary findings reported to the departmental training grant advisory committee responsible for accepting/hiring fellows and following their progress. In addition, an external scientific oversight board meets yearly to offer advice to the program directors on all aspects of the training program. The overall intent of the program is to develop the next generation of clinician scientist leaders in anesthesiology and perioperative medicine research.