Training Program in Molecular and Cellular Biology

分子和细胞生物学（MCB）培训计划的目标是提供最高质量的 基础分子和细胞生物学的跨学科科学和学术培训， 不同的背景，谁将成为未来的领导者在生物医学科学。本申请寻求 支持一个长期成功的计划。MCB T32博士前学生形成一个完整的，但 威尔康奈尔大学医学科学研究生院（WCGS）的联盟BCMB计划的独特部分。 BCMB是WCGS研究的7个项目中的3个的联合研究生培训奋进：生物化学和 结构生物学（BSB），细胞和发育生物学（CBG）和分子生物学（MB）。WCGS 它本身是一个独特的63年的合作伙伴关系，由威尔康奈尔医学院（WCMC）和 Sloan-Kettering Institute（SKI）. MCB培训计划包括80名选定的教师，他们是 BCMB联盟，并作为研究生导师有很强的集体经验。研究兴趣 MCB教师的主题由六个具体领域代表，每个领域都包括世界领导人， 领域：细胞结构和功能，分子生物化学和生物物理学，核酸交易和 基因组完整性，病毒和微生物的分子和细胞生物学，组织生物学与发育， 癌症生物学在他们的第一年，MCB学员参加核心课程的5个必修课程和3个 实验室轮换一年级的学生由他们的一年级顾问密切监督，他协助他们 在第一学年结束时选择论文导师。在他们的第二年，学生必须通过书面和 ACE（入学考试）的口头部分，并成立一个特别委员会来监督他们的论文 中求进工作总在第一年和第二年，所有学生完成一门负责任的研究行为课程， 定量生物学课程侧重于统计学和计算生物学。除了表演原创之外 实验室研究，二年级和更高年级的学生参加选修课和“焦点小组” 讨论会。MCB学生由培训项目总监指导，参加专门设计的 培训计划的活动，并建议在研究生课程的教学助理。进展 MCB受训人员每年通过个人发展计划进行监测。BCMB计划 董事，第一年的学生顾问，和招生主席，与培训的项目总监共同 格兰特，形成管理委员会的MCB培训计划。一个独立的高级顾问委员会 提供监督和评估。目前，BCMB计划平均每年招收21名学生 由WCGS提供的机构资金，加上培训补助金资金。该方案的规模不断扩大， 质量近年来，由于我们的学生和新教师招聘在这两个机构的成功， 它吸引了相当数量的优秀候选人，符合资格成为MCB学员。我们 因此，请求延长这一赠款，每年资助8名博士前学员。

The objective of the Molecular and Cellular Biology (MCB) Training Program is to provide the highest quality interdisciplinary scientific and academic training in fundamental molecular and cell biology to individuals from diverse backgrounds who will become future leaders in the biomedical sciences. This application is seeking renewal of support for a long-standing successful program. MCB T32 predoctoral students form an integral yet distinct part of the allied BCMB program of Weill Cornell Graduate School of Medical Sciences (WCGS). BCMB is a combined graduate training endeavor of 3 of the 7 programs of study at WCGS: Biochemistry and Structural Biology (BSB), Cell and Developmental Biology (CBG), and Molecular Biology (MB). The WCGS itself is a unique 63-year partnership composed of faculty from Weill Cornell Medical College (WCMC) and the Sloan-Kettering Institute (SKI). The MCB training program includes 80 selected faculty who are members of the BCMB alliance and have a strong collective experience as graduate mentors. Research interests of the MCB faculty are thematically represented by six specific areas, each of which includes world leaders in their field: Cell Structure and Function, Molecular Biochemistry and Biophysics, Nucleic Acid Transactions and Genomic Integrity, Molecular & Cell Biology of Viruses and Microorganisms, Tissue Biology & Development, and Cancer Biology. During their first year, MCB trainees take a Core Curriculum of 5 required courses and 3 laboratory rotations. First year students are closely monitored by their First Year Advisor, who assists them in choosing a thesis mentor at the end of Year 1. During their second year, students must pass the written and oral portions of the ACE (Admission to Candidacy Exam) and form a Special Committee to monitor their thesis progress. In years 1 and 2, all students complete a course in Responsible Conduct of Research, and a Quantitative Biology course focusing on statistics and computational biology. In addition to performing original laboratory research, second year and more senior students enroll in elective courses and `Focus Group' discussion sessions. MCB students are guided by the Training Program Director, attend specially designed Training Program events, and are recommended to be Teaching Assistants in graduate courses. Progress of the MCB trainees is monitored annually with the use of Individual Development Plans. The BCMB Program Directors, 1st year Student Advisors, and Admissions Chair, jointly with the Program Director of the Training Grant, form the Governing Committee of the MCB training program. A separate committee of Senior Advisors provides oversight and evaluation. Currently, the BCMB Program admits an average of 21 students per year on institutional funds provided by WCGS, plus Training Grant funds. The Program has grown in size and quality in recent years, due to the success of our students and new faculty recruitment at both institutions, and it has attracted a significant number of outstanding candidates that are eligible as MCB trainees. We are therefore requesting renewal of this grant, with funding to support a total of 8 predoctoral trainees per year.