Cancer Center Support Grant - UT Southwestern Medical Center

 描述(由申请人提供)：德克萨斯大学西南西蒙斯癌症中心正在提交这份竞争续签申请，申请6-10年的癌症中心支持拨款。西蒙斯癌症中心是一个矩阵中心，整合了德克萨斯大学西南医学中心及其附属医院系统、德克萨斯大学西南分校医疗系统、Parkland健康与医院系统、达拉斯儿童医疗中心和沃斯堡蒙克里夫癌症研究所的癌症研究、临床癌症护理和癌症控制服务。与德克萨斯大学公共卫生学院达拉斯地区校区的研究合作是一个公共卫生硕士和博士授予项目，位于UTSW校区，为该中心带来公共卫生专业知识和培训机会。西蒙斯癌症中心的首要使命是利用这些关系创造新的知识，以改善达拉斯、德克萨斯州北部和全国的癌症结果。西蒙斯癌症中心的164名成员被组织成五个科学项目--发展与癌症、癌细胞网络、化学与癌症、癌症实验治疗以及人口科学与癌症控制。这些项目具有高度的互动性，在过去的资助期内，授予了22名多名研究人员的赠款，合作出版率为52%。申请高级领导人和项目负责人、规划和评估、发展资金、行政、早期临床研究支持、方案审查和监测系统、临床方案和数据管理，以及六个共享资源，其中两个在研究设计和数据分析组(生物统计学、生物信息学)；四个在翻译组(高通量筛查、小动物成像、活细胞成像和组织管理)。CCSG对这些组成部分的支持得到了机构资金的补充，以确保中心拥有完成其使命所需的基础设施。此外，西蒙斯癌症中心创造了充满活力的教育和培训机会，旨在装备新一代科学家、医生和其他医疗保健提供者，在癌症发现、临床护理和控制方面发挥作用。 西蒙斯癌症中心整合了德克萨斯大学西南医学中心及其附属医院系统的癌症研究、临床癌症护理和癌症控制外展服务。该中心的首要使命是利用这些关系和可用的特殊资源来改善达拉斯-沃斯堡(DFW)地区和全国的癌症结果。

 DESCRIPTION (provided by applicant): The University of Texas Southwestern Simmons Cancer Center is submitting this competitive renewal application for a Cancer Center Support Grant, Years 6-10. The Simmons Cancer Center is organized as a matrix center that integrates cancer research, clinical cancer care, and cancer control outreach across the University of Texas Southwestern (UTSW) Medical Center and its affiliated hospital systems, UTSW Health System, Parkland Health and Hospital System, Children's Medical Center of Dallas, and UTSW Moncrief Cancer Institute in Fort Worth. A research affiliation with the Dallas Regional Campus of the University of Texas School of Public Health, an MPH and PhD granting program located on the UTSW campus, brings public health expertise and training opportunities into the center. The overriding mission of the Simmons Cancer Center is to leverage these affiliations to create new knowledge to improve cancer outcomes in Dallas, North Texas, and the nation. The 164 members of the Simmons Cancer Center are organized into five scientific programs- Development and Cancer, Cancer Cell Networks, Chemistry and Cancer, Experimental Therapeutics of Cancer, and Population Science and Cancer Control. These programs are highly interactive, with 22 multi-investigator grants awarded and a 52% collaborative publication ratio over the past grant period. Funds are requested in the application for Senior Leaders and Program Leaders, Planning and Evaluation, Developmental Funds, Administration, Early Phase Clinical Research Support, Protocol Review and Monitoring System, Clinical Protocol and Data Management, and six shared resources including two in a research design and data analytics grouping (biostatistics, bioinformatics); and four in a translational grouping (high throughput screening, small animal imaging, live cell imaging, and tissue management). CCSG support for these components is supplemented by institutional funds to ensure that the center has the infrastructure required to achieve its mission. In addition, the Simmons Cancer Center has created dynamic educational and training opportunities designed to equip a new generation of scientists, physicians, and other health care providers to make a difference in cancer discovery, clinical care, and control. The Simmons Cancer Center integrates cancer research, clinical cancer care, and cancer control outreach across the University of Texas Southwestern Medical Center and its affiliated hospital systems. The overriding mission of the center is to leverage these affiliations and the exceptional resources available to improve cancer outcomes in the Dallas-Fort Worth (DFW) region and the nation.