Health Delivery Systems Center for Diabetes Translational Research

A.中心概述项目摘要 糖尿病在美国是一个重大的健康负担，影响着2000多万人 每年要花费1000多亿美元。2型糖尿病(T2 DM)的患病率正在上升 迅速；疾控中心估计，到2050年，多达三分之一的美国人将患有糖尿病。背负着 T2 DM在少数民族和社会经济地位较低的人群中尤为严重。这个 预防和治疗2型糖尿病的证据基础是任何慢性病中最可靠的之一： 临床试验表明，心脏代谢疗法在预防心脏病死亡率和发病率方面的效果 糖尿病，以及糖尿病预防计划(DPP)等项目已经表明，糖尿病可以 在高危患者中可以预防。然而，糖尿病的整体护理质量仍然不是最好的， 在糖尿病护理和预防方面仍然存在重大差距，有效人群很少-- 有系统地减少、预防糖尿病和降低糖尿病风险的努力。计划可以有效地 将高质量、循证的糖尿病预防和治疗转化为广泛的实践 迫切需要。 为了回应这一需求，凯撒永久北加州分部的糖尿病研究人员 研究，健康伙伴教育和研究研究所，哈佛朝圣者健康护理研究所，和 加州大学旧金山分校(UCSF)创建了糖尿病医疗服务系统中心 2011年的翻译研究(HDS-CDTR)(P30 DK092924)。此CDTR促进并支持翻译 附属于医疗保健系统研究的医疗保健提供系统内的糖尿病研究 与加州大学旧金山分校合作建立了卫生组织研究网络(以前称为卫生组织研究网络)。HDS-CDTR汇集了一个 由久负盛名的调查人员组成的多学科网络，有很强的联邦和 糖尿病转化研究的基金资助。HDS-CDTR的结构围绕三个翻译 医疗保健差距、糖尿病和肥胖症预防以及健康信息领域的研究中心 技术HDS-CDTR调查人员与递送系统有着密切的关系，从大型 向作为翻译关键合作伙伴的安全网提供商网络提供综合交付系统 对现实世界临床环境的有效干预。我们的CDTR将继续成为以下方面的强大资源- 通过其资源核心在全美范围内提供资源交付系统，这将继续并扩大我们的 支持这些系统努力提供高质量的糖尿病预防和护理。此外， HDS-CDTR正在扩大其使命，通过创建一个新的核心来解决服务不足的问题 将与初级和高级代表不足少数民族(URM)建立牢固伙伴关系的人群 莫尔豪斯医学院的研究人员。

A. Center Overview Project Abstract Diabetes mellitus is a significant health burden in the United States, affecting more than 20,000,000 people and costing more than $100 billion annually. The prevalence of Type 2 diabetes (T2DM) is growing rapidly; the CDC estimates that up to 1/3 of Americans will have diabetes by the year 2050. The burden of T2DM is particularly great among ethnic minority populations and those of lower socioeconomic status. The evidence base for the prevention and care of T2DM is one of the most well-established of any chronic illness: clinical trials have shown the efficacy of cardiometabolic therapies in preventing mortality and morbidity in diabetes, and programs such as the Diabetes Prevention Program (DPP) have demonstrated that diabetes can be prevented in high-risk patients. However, the overall quality of care for diabetes remains sub-optimal, significant disparities in diabetes care and prevention persist, and there are very few effective population- based efforts to systematically reduce prevent diabetes and reduce diabetes risk. Programs that can effectively translate high-quality, evidence-based diabetes prevention and treatment into widespread practice are desperately needed. In response to this need, diabetes researchers at the Kaiser Permanente Northern California Division of Research, HealthPartners Institute for Education and Research, Harvard Pilgrim Health Care Institute, and the University of California San Francisco (UCSF) created the Health Delivery Systems Center for Diabetes Translational Research (HDS-CDTR) in 2011 (P30 DK092924). This CDTR fosters and supports translational research in diabetes within health care delivery systems affiliated with the Health Care Systems Research Network (formerly known as the HMO Research Network) and with UCSF. The HDS- CDTR brings together a multi-disciplinary network of well-established investigators with a strong history of receiving federal and foundation funding in diabetes translational research. The HDS-CDTR is structured around three Translational Research Cores in the areas of health care disparities; diabetes and obesity prevention; and health information technology. HDS-CDTR investigators have strong relationships with delivery systems, ranging from large integrated delivery systems to networks of safety net providers that serve as key partners for translating effective interventions into real-world clinical settings. Our CDTR will continue to be a strong resource to under- resourced delivery systems across the U.S. through its Resource Core, which will continue and expand our support of these systems in their efforts to provide high quality diabetes prevention and care. In addition, the HDS-CDTR is expanding its mission to address disparities through the creation of a new Core for Underserved Populations that will develop a strong partnership with junior and senior Underrepresented Minority (URM) investigators at the Morehouse School of Medicine.