Pilot Projects Program

试点项目计划

• 批准号: 8948616
• 负责人: Sharon Irene Smith Rounds
• 金额: $ 55.77万
• 依托单位: BROWN UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-07-01 至 2021-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8948616
• 关键词: Academic Medical Centers; Advanced Development; Advisory Committees; Area; Attention; Award; Basic Science; Caring; Centers of Research Excellence; Clinical Research; Clinical Sciences; Clinical Trials; Collaborations; Communities; Data; Development; Discipline; Funding; Grant; Grant Review; Growth; Health Policy; Hospitals; Institution; Longevity; Mentors; Methodology; New England; Pilot Projects; Positioning Attribute; Preparation; Process; Public Health; Research; Research Personnel; Rhode Island; Series; Site; System; Testing; Translational Research; United States National Institutes of Health; Universities; University Hospitals; Veterans; Work; abstracting; base; experience; health disparity; interdisciplinary collaboration; meetings; programs; response; symposium; training opportunity

ABSTRACT – PILOT PROJECTS PROGRAM Advancing the development of clinical and translational research in Rhode Island is a critical need. Rhode Island institutions have a tradition of providing Pilot Projects support, but these awards have generally not been designated to support clinical and translational research. Thus, there is an unmet need to enhance funding of Clinical and Translational Research in Rhode Island that would be met by the RI-CCTS. We propose establishment of a Pilot Project Grants Program that is trans-disciplinary and translational with the following Specific Aims: 1. Enhance the quality and quantity of clinical and translational research in Rhode Island by funding Pilot Projects spanning the research spectrum from T1 to T4 and by developing clinical and translational research collaborations of co-PI's. 2. Promote selected high impact clinical and translational research areas via Emerging Areas of Research Symposia at institutions in Rhode Island, in collaboration with existing INBRE and COBRE programs. In the Pilot Projects Program, junior investigators (or more senior investigators transitioning to a translational research focus) will have the opportunity to apply for small grants of one year duration with an option of applying for a second year. In order to stimulate interdisciplinary collaboration, each Pilot Project grant will have two co-PI's from different disciplines. Two senior investigators will be designated as mentors to advise on grant preparation and conduct of the research. One mentor will have specific background in methodology or basic science, and the other mentor will have clinical science expertise. At least one of the Pilot Projects awarded through the RI-CCTS each year will include a clinical trial. In order to stimulate Clinical and Translational Research in high impact areas, the Pilot Projects Program Advisory Committee will work with the IDeA programs funded in RI to develop an annual research symposium on relevant topics. Symposia sites will rotate among Brown University, the Affiliated Hospitals, and the University of Rhode Island. The Pilot Projects Program will be led by Sharon Rounds with Deputy Leader Michelle Lally. It will be supported by an Advisory Committee that includes representatives from the Lifespan and Care New England Hospital Systems, the Providence Veterans Affairs Medical Center, the University of Rhode Island, and Brown University. The Advisory Committee will oversee application and review processes and, in conjunction with the RI-CCTS Internal Advisory Committee (IAC), will determine prioritization of research topics. Particular attention will be paid to support of clinical and translational research in areas of health disparities in Rhode Island. The Pilot Projects Program will leverage professional development opportunities, functionality and facilities offered by other Key Components (KC) of the RI-CCTS. The Pilot Projects Program will be an integral part of the RI-CCTS, providing opportunities to perform collaborative Clinical and Translational Research and to interact with other investigators to stimulate new research.

摘要-试点项目方案 推动罗德岛州临床和转化性研究的发展是一项迫切的需要。罗德岛 岛屿机构有提供试点项目支助的传统，但这些奖项通常没有 旨在支持临床和转化性研究。因此，有一种未得到满足的需求，即加强对 罗德岛的临床和转译研究，将由RI-CCTS满足。我们建议 建立一个具有跨学科和可转换性的试点项目资助计划，内容如下 具体目标：1.提高罗德岛临床和翻译研究的质量和数量 通过资助从T1到T4的研究范围的试点项目和通过开发 联合PI的临床和翻译研究合作。2.推广选定的高影响临床 和翻译研究领域，通过罗德岛各机构的新兴研究研讨会领域 岛屿，与现有的INBRE和COBRE方案合作。在试点项目计划中，初级 调查人员(或更多向翻译研究重点过渡的高级调查人员)将拥有 有机会申请为期一年的小额赠款，并可选择申请第二年。按顺序 为了促进跨学科合作，每个试点项目将有两个来自不同领域的合作PI 纪律。两名高级调查员将被指定为导师，就赠款的准备和实施提供建议 这项研究的。一位导师将在方法论或基础科学方面有特定的背景，而另一位导师将拥有特定的背景 Mentor将拥有临床科学专业知识。至少有一个通过国际扶轮-CCTS授予的试点项目 每年将包括一项临床试验。为了促进高影响力的临床和翻译研究 试点项目计划咨询委员会将与国际扶轮资助的IDEA计划合作，以 就相关主题开展年度研究研讨会。座谈会地点将在布朗大学之间轮换， 附属医院和罗德岛大学。试点项目计划将由沙龙领导 与副领袖米歇尔·拉利进行了交谈。它将得到一个咨询委员会的支持，该委员会包括 来自寿命和关怀新英格兰医院系统、普罗维登斯退伍军人事务部的代表 医学中心、罗德岛大学和布朗大学。咨询委员会将监督 申请和审查程序，并将与RI-CCTS内部咨询委员会(IAC)合作， 确定研究主题的优先顺序。将特别注意支持临床和 罗德岛州健康差距地区的翻译研究。试点项目计划将利用 其他关键组件(KC)提供的专业发展机会、功能和设施 国际扶轮CCTS。试点项目计划将是RI-CCTS的组成部分，提供以下机会 进行合作的临床和转译研究，并与其他研究人员互动以刺激 新的研究。