Pilot Projects Program

试点项目计划

• 批准号: 8948616
• 负责人: Sharon Irene Smith Rounds
• 金额: $ 55.77万
• 依托单位: BROWN UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-07-01 至 2021-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8948616
• 关键词: Academic Medical Centers; Advanced Development; Advisory Committees; Area; Attention; Award; Basic Science; Caring; Centers of Research Excellence; Clinical Research; Clinical Sciences; Clinical Trials; Collaborations; Communities; Data; Development; Discipline; Funding; Grant; Grant Review; Growth; Health Policy; Hospitals; Institution; Longevity; Mentors; Methodology; New England; Pilot Projects; Positioning Attribute; Preparation; Process; Public Health; Research; Research Personnel; Rhode Island; Series; Site; System; Testing; Translational Research; United States National Institutes of Health; Universities; University Hospitals; Veterans; Work; abstracting; base; experience; health disparity; interdisciplinary collaboration; meetings; programs; response; symposium; training opportunity

ABSTRACT – PILOT PROJECTS PROGRAM Advancing the development of clinical and translational research in Rhode Island is a critical need. Rhode Island institutions have a tradition of providing Pilot Projects support, but these awards have generally not been designated to support clinical and translational research. Thus, there is an unmet need to enhance funding of Clinical and Translational Research in Rhode Island that would be met by the RI-CCTS. We propose establishment of a Pilot Project Grants Program that is trans-disciplinary and translational with the following Specific Aims: 1. Enhance the quality and quantity of clinical and translational research in Rhode Island by funding Pilot Projects spanning the research spectrum from T1 to T4 and by developing clinical and translational research collaborations of co-PI's. 2. Promote selected high impact clinical and translational research areas via Emerging Areas of Research Symposia at institutions in Rhode Island, in collaboration with existing INBRE and COBRE programs. In the Pilot Projects Program, junior investigators (or more senior investigators transitioning to a translational research focus) will have the opportunity to apply for small grants of one year duration with an option of applying for a second year. In order to stimulate interdisciplinary collaboration, each Pilot Project grant will have two co-PI's from different disciplines. Two senior investigators will be designated as mentors to advise on grant preparation and conduct of the research. One mentor will have specific background in methodology or basic science, and the other mentor will have clinical science expertise. At least one of the Pilot Projects awarded through the RI-CCTS each year will include a clinical trial. In order to stimulate Clinical and Translational Research in high impact areas, the Pilot Projects Program Advisory Committee will work with the IDeA programs funded in RI to develop an annual research symposium on relevant topics. Symposia sites will rotate among Brown University, the Affiliated Hospitals, and the University of Rhode Island. The Pilot Projects Program will be led by Sharon Rounds with Deputy Leader Michelle Lally. It will be supported by an Advisory Committee that includes representatives from the Lifespan and Care New England Hospital Systems, the Providence Veterans Affairs Medical Center, the University of Rhode Island, and Brown University. The Advisory Committee will oversee application and review processes and, in conjunction with the RI-CCTS Internal Advisory Committee (IAC), will determine prioritization of research topics. Particular attention will be paid to support of clinical and translational research in areas of health disparities in Rhode Island. The Pilot Projects Program will leverage professional development opportunities, functionality and facilities offered by other Key Components (KC) of the RI-CCTS. The Pilot Projects Program will be an integral part of the RI-CCTS, providing opportunities to perform collaborative Clinical and Translational Research and to interact with other investigators to stimulate new research.

摘要 – 试点项目计划 推动罗德岛州临床和转化研究的发展是一项迫切需要。罗德 岛屿机构有提供试点项目支持的传统，但这些奖项通常没有得到认可。 指定用于支持临床和转化研究。因此，增加资金投入的需求尚未得到满足。 罗德岛州的临床和转化研究将由 RI-CCTS 负责。我们建议 建立一个跨学科和转化性的试点项目资助计划，其中包括以下内容 具体目标： 1. 提高罗德岛临床和转化研究的质量和数量 岛通过资助涵盖从 T1 到 T4 研究范围的试点项目并开发 共同 PI 的临床和转化研究合作。 2. 促进选定的高影响力临床 和转化研究领域，通过罗德岛机构的新兴研究领域研讨会 Island，与现有的 INBRE 和 COBRE 项目合作。在试点项目计划中，初级 研究人员（或更高级的研究人员转向转化研究重点）将拥有 有机会申请为期一年的小额赠款，并可以选择申请第二年。为了 为了促进跨学科合作，每个试点项目拨款将有来自不同领域的两名联合 PI 学科。两名高级研究员将被指定为导师，就拨款准备和实施提供建议 研究的。一位导师将具有方法论或基础科学的特定背景，另一位导师将具有方法论或基础科学的特定背景 导师将具有临床科学专业知识。至少一个通过 RI-CCTS 授予的试点项目 每年都会包括一项临床试验。为了促进高影响力的临床和转化研究 领域，试点项目计划咨询委员会将与 RI 资助的 IDeA 计划合作， 举办有关相关主题的年度研究研讨会。研讨会地点将在布朗大学、 附属医院和罗德岛大学。试点项目计划将由沙龙领导 与副党魁米歇尔·拉利 (Michelle Lally) 会面。它将得到咨询委员会的支持，其中包括 来自新英格兰生命与护理医院系统、普罗维登斯退伍军人事务部的代表 医学中心、罗德岛大学和布朗大学。咨询委员会将监督 申请和审查流程，并与 RI-CCTS 内部咨询委员会 (IAC) 一起， 确定研究课题的优先顺序。将特别关注临床和 罗德岛州健康差异领域的转化研究。试点项目计划将利用 其他关键组件 (KC) 提供的专业发展机会、功能和设施 RI-CCTS。试点项目计划将成为 RI-CCTS 的一个组成部分，为 进行协作临床和转化研究并与其他研究人员互动以刺激 新的研究。