Pilot Projects Program

试点项目计划

• 批准号: 8948616
• 负责人: Sharon Irene Smith Rounds
• 金额: $ 55.77万
• 依托单位: BROWN UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-07-01 至 2021-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8948616
• 关键词: Academic Medical Centers; Advanced Development; Advisory Committees; Area; Attention; Award; Basic Science; Caring; Centers of Research Excellence; Clinical Research; Clinical Sciences; Clinical Trials; Collaborations; Communities; Data; Development; Discipline; Funding; Grant; Grant Review; Growth; Health Policy; Hospitals; Institution; Longevity; Mentors; Methodology; New England; Pilot Projects; Positioning Attribute; Preparation; Process; Public Health; Research; Research Personnel; Rhode Island; Series; Site; System; Testing; Translational Research; United States National Institutes of Health; Universities; University Hospitals; Veterans; Work; abstracting; base; experience; health disparity; interdisciplinary collaboration; meetings; programs; response; symposium; training opportunity

ABSTRACT – PILOT PROJECTS PROGRAM Advancing the development of clinical and translational research in Rhode Island is a critical need. Rhode Island institutions have a tradition of providing Pilot Projects support, but these awards have generally not been designated to support clinical and translational research. Thus, there is an unmet need to enhance funding of Clinical and Translational Research in Rhode Island that would be met by the RI-CCTS. We propose establishment of a Pilot Project Grants Program that is trans-disciplinary and translational with the following Specific Aims: 1. Enhance the quality and quantity of clinical and translational research in Rhode Island by funding Pilot Projects spanning the research spectrum from T1 to T4 and by developing clinical and translational research collaborations of co-PI's. 2. Promote selected high impact clinical and translational research areas via Emerging Areas of Research Symposia at institutions in Rhode Island, in collaboration with existing INBRE and COBRE programs. In the Pilot Projects Program, junior investigators (or more senior investigators transitioning to a translational research focus) will have the opportunity to apply for small grants of one year duration with an option of applying for a second year. In order to stimulate interdisciplinary collaboration, each Pilot Project grant will have two co-PI's from different disciplines. Two senior investigators will be designated as mentors to advise on grant preparation and conduct of the research. One mentor will have specific background in methodology or basic science, and the other mentor will have clinical science expertise. At least one of the Pilot Projects awarded through the RI-CCTS each year will include a clinical trial. In order to stimulate Clinical and Translational Research in high impact areas, the Pilot Projects Program Advisory Committee will work with the IDeA programs funded in RI to develop an annual research symposium on relevant topics. Symposia sites will rotate among Brown University, the Affiliated Hospitals, and the University of Rhode Island. The Pilot Projects Program will be led by Sharon Rounds with Deputy Leader Michelle Lally. It will be supported by an Advisory Committee that includes representatives from the Lifespan and Care New England Hospital Systems, the Providence Veterans Affairs Medical Center, the University of Rhode Island, and Brown University. The Advisory Committee will oversee application and review processes and, in conjunction with the RI-CCTS Internal Advisory Committee (IAC), will determine prioritization of research topics. Particular attention will be paid to support of clinical and translational research in areas of health disparities in Rhode Island. The Pilot Projects Program will leverage professional development opportunities, functionality and facilities offered by other Key Components (KC) of the RI-CCTS. The Pilot Projects Program will be an integral part of the RI-CCTS, providing opportunities to perform collaborative Clinical and Translational Research and to interact with other investigators to stimulate new research.

摘要-试点项目 推进临床和转化研究在罗得岛的发展是一个关键的需要。罗德 岛屿机构有提供试点项目支助的传统，但这些奖项一般没有得到 用于支持临床和转化研究。因此，在增加对以下方面的供资方面的需求尚未得到满足： RI-CCTS将满足罗得岛的临床和转化研究。我们提出 建立一个跨学科和翻译的试点项目赠款计划，包括以下内容 具体目标：1。提高罗得岛临床和转化研究的质量和数量 通过资助涵盖T1至T4研究范围的试点项目， 共同主要研究者的临床和转化研究合作。2.促进选定的高影响力临床 和翻译研究领域通过研究研讨会的新兴领域在罗德岛的机构 岛，与现有的INBRE和COBRE计划合作。在试点项目中，初级 研究者（或更高级的研究者过渡到翻译研究重点）将有 有机会申请为期一年的小额赠款，并可选择申请第二年。为了 为了促进跨学科合作，每个试点项目赠款将有两个来自不同领域的联合PI 学科两名资深调查员将被指定为导师，就拨款的准备和实施提供意见 的研究。一位导师将具有方法学或基础科学的特定背景，另一位导师将具有方法学或基础科学的特定背景。 导师将具有临床科学专业知识。至少一个通过RI-CCTS授予的试点项目 每年将进行一次临床试验。为了刺激临床和转化研究的高影响力 在某些领域，试办计画计画谘询委员会将与国际扶轮资助的IDEA计画合作， 每年就相关主题举办一次研究专题讨论会。研讨会地点将在布朗大学， 附属医院和罗得岛大学。试点项目计划将由沙龙领导 与副领导人米歇尔·拉里（Michelle Lally）会面它将得到一个咨询委员会的支持，该委员会包括 来自寿命和护理新英格兰医院系统、普罗维登斯退伍军人事务部的代表 医学中心、罗得岛大学和布朗大学。咨询委员会将监督 申请和审查程序，并与RI-CCTS内部咨询委员会（IAC）一起，将 确定研究课题的优先次序。将特别注意支持临床和 在罗得岛的健康差距领域的转化研究。试点项目计划将利用 专业发展的机会，功能和设施提供的其他关键组成部分（KC）的 RI-CCTS。试点项目计划将是RI-CCTS的一个组成部分， 进行合作临床和转化研究，并与其他研究者互动，以促进 新的研究