RI-Center for Clinical and Translational Science

RI-临床和转化科学中心

• 批准号: 10403751
• 负责人: Sharon Irene Smith Rounds
• 金额: $ 29.79万
• 依托单位: BROWN UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-07-01 至 2023-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10403751
• 关键词: Address; Area; Award; Basic Science; Big Data; Biological; Biometry; Caring; Clinical; Clinical Research; Clinical Sciences; Clinical effectiveness; Collaborations; Communities; Community Outreach; Core Facility; Data; Development; Discipline of Nursing; Environment; Epidemiology; Evolution; Extramural Activities; Fostering; Funding; Funding Opportunities; Future; Goals; Government Agencies; Grant; Health; Health Policy; Health Priorities; Health Services; Health system; Healthcare Systems; Home; Hospitals; Human Resources; Infrastructure; Institutes; Institution; Lead; Longevity; Mental Health; Mentors; Modeling; National Institute of General Medical Sciences; New England; Nonprofit Organizations; Outcome; Pharmacy facility; Pilot Projects; Population; Positioning Attribute; Program Development; Program Evaluation; Protocols documentation; Public Health; Publications; Research; Research Design; Research Infrastructure; Research Personnel; Research Proposals; Research Support; Resources; Rhode Island; Services; Teacher Professional Development; Testing; Training; Translating; Translational Research; United States National Institutes of Health; Universities; University Hospitals; Vulnerable Populations; bench to bedside; biomedical informatics; career; career development; clinical application; clinical center; clinical infrastructure; clinical practice; community engaged research; community engagement; community organizations; coronavirus disease; cost; demographics; health care delivery; health disparity; health equity; hospital organization; improved; innovation; laboratory development; multidisciplinary; organizational structure; patient oriented; prevent; programs; success; translational research program; translational scientist; virtual

ABSTRACT – OVERALL The universities, hospitals, government agencies and community organizations in Rhode Island are well positioned to bridge the gaps between the worlds of clinical and basic science. Rhode Island’s small size, population demographics, and organizational structure are assets and present opportunities to implement and test transformative clinical and translational research. The health care delivery environment within the state is highly conducive to clinical research due to the relatively limited number of health care systems. Further contributing to Rhode Island’s translational research infrastructure are a number of well-organized Institutional Developmental Award (IDeA) Programs, each with core facility, faculty development and collaborative research resources. But despite Rhode Island’s impressive educational institutions, streamlined clinical environment, and successful IDeA sponsored research and mentoring programs, the majority of these resources have not been coordinately focused towards developing a multi-institutional, clinical and translational research infrastructure that would serve to improve the effectiveness of clinical practice and health care policy in Rhode Island. The objective of the Advance Clinical and Translation Research Award (Advance-CTR) is to bridge these infrastructure gaps by creating an overarching, multidisciplinary, central organization to better coordinate and leverage existing resources for program management and thereby provide the infrastructure necessary to address current and future health concerns in Rhode Island. The goals of the Advance-CTR are to: 1. Educate, mentor and encourage young investigators in clinical research professional development. 2. Eliminate the obstacles that may prevent researchers from pursuing clinical research initiatives that can lead to funded research programs. 3. Bring together the diverse clinical research resources to provide a virtual home that facilitates new collaborations and enhanced efficiencies. 4. Facilitate research to gather preliminary data necessary for developing competitive research proposals. 5. Provide contemporary infrastructure for clinical and translational research including research planning and implementation, advanced biostatistics and epidemiology support and biomedical informatics. 6. Foster coordination between translational researchers at our participating entities so as to create new productive collaborations with translational outcomes. 7. Sustain a clinical translational research environment by providing the necessary management and coordination of resources. 8. Create an innovative Tracking and Evaluation program that will combine support requests with use and cost data and apply lessons learned in the CTSA program to the CTR environment.

摘要 – 总体 罗德岛州的大学、医院、政府机构和社区组织状况良好 旨在弥合临床和基础科学领域之间的差距。罗德岛州面积狭小， 人口统计数据和组织结构是资产，并提供实施和实施的机会 测试变革性临床和转化研究。该州内的医疗保健提供环境是 由于医疗保健系统数量相对有限，非常有利于临床研究。更远 许多组织良好的机构为罗德岛州的转化研究基础设施做出了贡献 发展奖 (IDeA) 项目，每个项目都有核心设施、教师发展和协作 研究资源。尽管罗德岛州拥有令人印象深刻的教育机构，但简化的临床 环境、成功的 IDeA 赞助的研究和指导计划，其中大部分 资源尚未协调集中用于发展多机构、临床和 转化研究基础设施将有助于提高临床实践的有效性和 罗德岛州的医疗保健政策。高级临床和转化研究奖的目标 (Advance-CTR) 旨在通过创建一个总体性的、多学科的、集中的解决方案来弥合这些基础设施差距。 组织更好地协调和利用现有资源进行计划管理，从而 提供解决罗德岛州当前和未来健康问题所需的基础设施。目标 Advance-CTR 的目的是： 1. 教育、指导和鼓励年轻研究者进行临床研究专业发展。 2. 消除可能阻碍研究人员开展临床研究举措的障碍 导致资助的研究项目。 3. 汇集多样化的临床研究资源，提供一个虚拟的家，促进新的研究 协作并提高效率。 4. 促进研究收集制定竞争性研究提案所需的初步数据。 5. 为临床和转化研究提供现代基础设施，包括研究规划 和实施、先进的生物统计学和流行病学支持以及生物医学信息学。 6. 促进参与实体的转化研究人员之间的协调，以创造新的成果 具有转化成果的富有成效的合作。 7. 通过提供必要的管理和支持来维持临床转化研究环境 资源协调。 8. 创建一个创新的跟踪和评估计划，将支持请求与使​​用和 成本数据并将 CTSA 计划中吸取的经验教训应用到 CTR 环境中。