Advance Clinical and Translational Research (Advance-CTR)

摘要--总体 罗德岛的大学、医院、政府机构和社区组织都很好 定位于弥合临床和基础科学世界之间的差距。罗德岛的面积很小， 人口统计数据和组织结构是资产，也是实施和 测试变革性临床和转化性研究。该州的医疗保健提供环境是 由于卫生保健系统的数量相对有限，因此非常有利于临床研究。进一步 为罗德岛的翻译研究基础设施做出贡献的是一些组织良好的机构 发展奖(IDEA)计划，每个计划都有核心设施、教师发展和协作 研究资源。但尽管罗德岛有令人印象深刻的教育机构，简化了临床 环境，以及成功的创意赞助的研究和指导计划，其中大部分 资源没有协调地集中在开发多机构、临床和 翻译研究基础设施，将有助于提高临床实践和 罗德岛州的医疗保健政策。先进临床与翻译研究奖的目标 (Advance-CTR)旨在通过创建统筹兼顾、多学科、集中的 组织更好地协调和利用计划管理的现有资源，从而 提供必要的基础设施，以解决罗德岛州目前和未来的健康问题。目标 ADVANCE-CTR的目标是： 1.在临床研究专业发展方面教育、指导和鼓励青年研究人员。 2.消除可能阻碍研究人员进行临床研究的障碍 引导资助研究项目。 3.汇聚不同的临床研究资源，提供一个虚拟家园，促进新的 协作和提高效率。 4.促进研究收集制定竞争性研究提案所需的初步数据。 5.为临床和转化性研究提供现代基础设施，包括研究规划 以及实施、先进的生物统计学和流行病学支持以及生物医学信息学。 6.促进我们参与实体的翻译研究人员之间的协调，以创造新的 富有成效的协作和翻译成果。 7.通过提供必要的管理和支持，维持临床转化型研究环境 协调资源。 8.创建一个创新的跟踪和评估计划，将支持请求与使用和 成本数据，并将CTSA计划中学到的经验教训应用到CTR环境中。

ABSTRACT – OVERALL The universities, hospitals, government agencies and community organizations in Rhode Island are well positioned to bridge the gaps between the worlds of clinical and basic science. Rhode Island’s small size, population demographics, and organizational structure are assets and present opportunities to implement and test transformative clinical and translational research. The health care delivery environment within the state is highly conducive to clinical research due to the relatively limited number of health care systems. Further contributing to Rhode Island’s translational research infrastructure are a number of well-organized Institutional Developmental Award (IDeA) Programs, each with core facility, faculty development and collaborative research resources. But despite Rhode Island’s impressive educational institutions, streamlined clinical environment, and successful IDeA sponsored research and mentoring programs, the majority of these resources have not been coordinately focused towards developing a multi-institutional, clinical and translational research infrastructure that would serve to improve the effectiveness of clinical practice and health care policy in Rhode Island. The objective of the Advance Clinical and Translation Research Award (Advance-CTR) is to bridge these infrastructure gaps by creating an overarching, multidisciplinary, central organization to better coordinate and leverage existing resources for program management and thereby provide the infrastructure necessary to address current and future health concerns in Rhode Island. The goals of the Advance-CTR are to: 1. Educate, mentor and encourage young investigators in clinical research professional development. 2. Eliminate the obstacles that may prevent researchers from pursuing clinical research initiatives that can lead to funded research programs. 3. Bring together the diverse clinical research resources to provide a virtual home that facilitates new collaborations and enhanced efficiencies. 4. Facilitate research to gather preliminary data necessary for developing competitive research proposals. 5. Provide contemporary infrastructure for clinical and translational research including research planning and implementation, advanced biostatistics and epidemiology support and biomedical informatics. 6. Foster coordination between translational researchers at our participating entities so as to create new productive collaborations with translational outcomes. 7. Sustain a clinical translational research environment by providing the necessary management and coordination of resources. 8. Create an innovative Tracking and Evaluation program that will combine support requests with use and cost data and apply lessons learned in the CTSA program to the CTR environment.