Pilot Projects Program

摘要-试点项目方案 虽然先进的CTR已经成为改变临床和翻译的质量和数量的催化剂 在罗德岛的研究(CTR)，仍然需要保持这些成果并不断发展，以解决 国家的健康优先事项与社区的参与。此外，我们还发现了新的未满足的 研究人员需要建立跨学科网络，加强基于社区的研究工作， 并支持对关键初步数据的奖励。这包括初级调查人员的启动补助金。 申请K奖。因此，在此次续签申请中，我们的目标是扩大试点项目计划 并在变革性进展的同时不断发展，以满足调查员的新需求 社区。试点项目计划(PPP)的具体目标是：(1)奖励影响大的试点项目 建议开发预防、诊断和治疗的转换方法的项目 (2)通过以下途径促进临床和翻译研究 确定跨学科、跨机构和以社区为基础的协作的优先顺序；(3) 促进初级教师先导计划获奖者的专业发展和校外资助 通过与Advance-CTR核心活动的协同作用；以及(4)加强合作和 罗德岛调查人员通过新兴研究领域的交流 研讨会。在PPP中，我们将继续征集、审查、授予、监督和评估一年的临床 以及初级调查人员和更高级调查人员过渡的翻译科学试点项目 至CTR焦点。将提供额外的小额赠款，以支持生成关键的初步 数据。我们还将促进跨学科和跨机构的调查人员网络，方法是资助 研究务虚会和小额试点拨款，以启动由此产生的新合作。我们将优先考虑临床 以及社区参与的研究和项目，以解决影响医疗服务不足的疾病 和/或对RI人群造成不成比例影响的疾病。PPP将继续利用专业人士 高级CTR的其他核心和服务提供的发展机会、功能和设施。在……里面 为了促进高影响力领域的技术创新和协作，公私合作伙伴关系将继续主办年度 相关专题研究座谈会。PPP将由Sharon Runds(核心领导)领导，共同领导 高拉夫·乔杜里。它将得到公私伙伴关系指导/审查委员会的支持，该委员会包括 来自所有伙伴机构的代表以及社区代表。PPP将继续是一个 先进的CTR的组成部分，催化协作和基于社区的临床和转换 促进健康的研究。 项目摘要/摘要页607

ABSTRACT – PILOT PROJECTS PROGRAM While Advance CTR has served as a catalyst to transform the quality and quantity of clinical and translational research (CTR) in Rhode Island, there remains a need to sustain these gains and evolve to address the state’s health priorities with engagement of the community. Furthermore, we have identified new unmet needs of investigators to foster interdisciplinary networks, to enhance community-based research efforts, and to support awards for key preliminary data. This includes jump-start grants for junior investigators applying for K awards. Therefore, in this renewal application, our goal is to expand the Pilot Project Program and build on the transformative progress while evolving to meet the new needs of the investigator community. The Specific Aims of the Pilot Projects Program (PPP) are to (1) award high-impact pilot projects that propose to develop translational approaches for prevention, diagnosis, and treatment of diseases and to improve health in RI; (2) facilitate clinical and translational research through prioritization of interdisciplinary, inter-institutional, and community-based collaborations; (3) promote professional development and extramural funding of junior faculty pilot project awardees through synergy with Advance-CTR Core activities; and (4) strengthen collaboration and communication among Rhode Island investigators through the Emerging Areas of Research Symposium. In the PPP, we will continue to solicit, review, award, oversee, and evaluate one-year clinical and translational science pilot projects from junior investigators and more senior investigators transitioning to a CTR focus. Additional Micro-Grants will be made available to support generation of key preliminary data. We will also promote interdisciplinary and inter-institutional networks of investigators by funding of research retreats and small pilot grants to jump-start resulting new collaborations. We will prioritize clinical and community engaged research and projects that address diseases that affect the medically underserved and/or diseases that disproportionately affect RI population. The PPP will continue to leverage professional development opportunities, functions, and facilities offered by other cores and services of Advance CTR. In order to stimulate CTR and collaboration in high impact areas, the PPP will continue to host an annual research symposium on relevant topics. The PPP will be led by Sharon Rounds (Core Lead) with co-Lead Gaurav Choudhary. It will be supported by the PPP Steering/Review Committee that includes representatives from all partner institutions plus community representatives. The PPP will continue to be an integral part of the Advance CTR, catalyzing collaborative and community-based Clinical and Translational Research to promote health. Project Summary/Abstract Page 607