Pilot Projects Program

试点项目计划

• 批准号: 10281528
• 负责人: Sharon Irene Smith Rounds
• 金额: $ 38.69万
• 依托单位: BROWN UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-07-01 至 2026-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10281528
• 关键词: Address; Adopted; Affect; Area; Award; COVID-19 pandemic; Centers of Research Excellence; Clinical; Clinical Research; Clinical Sciences; Collaborations; Communication; Communities; Community Outreach; Consultations; Data; Development; Diagnosis; Discipline; Disease; Environment; Evaluation; Event; Evolution; Extramural Activities; Faculty; Fostering; Funding; Generations; Goals; Grant; Health; Health Priorities; Health Promotion; Health Status; Healthcare; Hybrids; Institution; K-Series Research Career Programs; Lead; Letters; Mentors; Needs Assessment; Online Systems; Persons; Pilot Projects; Population; Prevention approach; Process; Public Health; Request for Applications; Research; Research Personnel; Research Project Grants; Review Committee; Rhode Island; Services; Surveys; Talents; Translational Research; base; catalyst; community based research; community engaged research; community engagement; experience; improved; innovation; inter-institutional; interdisciplinary collaboration; medically underserved; posters; programs; success; symposium; synergism; translational approach; translational scientist; virtual

ABSTRACT – PILOT PROJECTS PROGRAM While Advance CTR has served as a catalyst to transform the quality and quantity of clinical and translational research (CTR) in Rhode Island, there remains a need to sustain these gains and evolve to address the state’s health priorities with engagement of the community. Furthermore, we have identified new unmet needs of investigators to foster interdisciplinary networks, to enhance community-based research efforts, and to support awards for key preliminary data. This includes jump-start grants for junior investigators applying for K awards. Therefore, in this renewal application, our goal is to expand the Pilot Project Program and build on the transformative progress while evolving to meet the new needs of the investigator community. The Specific Aims of the Pilot Projects Program (PPP) are to (1) award high-impact pilot projects that propose to develop translational approaches for prevention, diagnosis, and treatment of diseases and to improve health in RI; (2) facilitate clinical and translational research through prioritization of interdisciplinary, inter-institutional, and community-based collaborations; (3) promote professional development and extramural funding of junior faculty pilot project awardees through synergy with Advance-CTR Core activities; and (4) strengthen collaboration and communication among Rhode Island investigators through the Emerging Areas of Research Symposium. In the PPP, we will continue to solicit, review, award, oversee, and evaluate one-year clinical and translational science pilot projects from junior investigators and more senior investigators transitioning to a CTR focus. Additional Micro-Grants will be made available to support generation of key preliminary data. We will also promote interdisciplinary and inter-institutional networks of investigators by funding of research retreats and small pilot grants to jump-start resulting new collaborations. We will prioritize clinical and community engaged research and projects that address diseases that affect the medically underserved and/or diseases that disproportionately affect RI population. The PPP will continue to leverage professional development opportunities, functions, and facilities offered by other cores and services of Advance CTR. In order to stimulate CTR and collaboration in high impact areas, the PPP will continue to host an annual research symposium on relevant topics. The PPP will be led by Sharon Rounds (Core Lead) with co-Lead Gaurav Choudhary. It will be supported by the PPP Steering/Review Committee that includes representatives from all partner institutions plus community representatives. The PPP will continue to be an integral part of the Advance CTR, catalyzing collaborative and community-based Clinical and Translational Research to promote health. Project Summary/Abstract Page 607

摘要 – 试点项目计划 虽然 Advance CTR 已成为改变临床和转化的质量和数量的催化剂 在罗德岛州的研究（CTR）中，仍然需要维持这些成果并不断发展以解决 州的卫生优先事项以及社区的参与。此外，我们还发现了新的未满足的 研究人员需要培育跨学科网络，加强基于社区的研究工作， 并支持关键初步数据的奖励。这包括为初级研究人员提供启动补助金 申请K奖。因此，在这次续签申请中，我们的目标是扩大试点项目计划 并以变革性进展为基础，同时不断发展以满足研究者的新需求 社区。试点项目计划 (PPP) 的具体目标是 (1) 奖励具有高影响力的试点项目 提议开发预防、诊断和治疗转化方法的项目 预防疾病并改善 RI 的健康状况； (2) 通过以下方式促进临床和转化研究 优先考虑跨学科、机构间和社区合作； (3) 促进初级教师试点项目获奖者的专业发展和校外资助 通过与 Advance-CTR 核心活动的协同作用； (4) 加强协作 罗德岛州研究人员通过新兴研究领域进行交流 座谈会。在 PPP 中，我们将继续征集、审查、授予、监督和评估一年的临床 初级研究人员和高级研究人员过渡的转化科学试点项目 到点击率焦点。将提供额外的小额赠款来支持关键初步成果的产生 数据。我们还将通过资助以下项目来促进跨学科和跨机构的研究人员网络： 研究务虚会和小额试点赠款，以启动新的合作。我们将优先考虑临床 和社区参与的研究和项目，解决影响医疗服务不足的人的疾病 和/或不成比例地影响 RI 人群的疾病。 PPP将继续发挥专业力量 Advance CTR 的其他核心和服务提供的开发机会、功能和设施。在 为了刺激高影响领域的点击率和合作，PPP 将继续举办年度活动 相关课题的研究研讨会。 PPP 将由 Sharon Rounds（核心负责人）和共同负责人领导 高拉夫·乔杜里。它将得到 PPP 指导/审查委员会的支持，其中包括 来自所有合作机构的代表以及社区代表。 PPP 将继续成为 Advance CTR 的组成部分，促进协作和基于社区的临床和转化 研究促进健康。 项目摘要/摘要第 607 页