Pathogenic flaviviruses: molecular mechanisms of disease, host response, and vaccines
Pathogenic flaviviruses: molecular mechanisms of disease, host response, and vaccines
批准号:
nhmrc : GNT1059794
负责人:
Prof Alexander Khromykh
金额:
$66.45万
依托单位国家:
澳大利亚
项目类别:
Research Fellowships
财政年份:
2014
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2014-01-01 至 --
中文摘要
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英文摘要
The application is aimed at advancing our understanding of the viral and host processes determining outcome of infection with pathogenic flaviviruses (i.e. West Nile virus) to the level allowing most comprehensive design of effective vaccines and anti-viral drugs. One of the aims is also to develop novel viral delivery vectors for cancer therapy based on self-replicating RNA of an attenuated Australian strain of West Nile virus, Kunjin.
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会议论文
From shape to function: how structured RNA defines insect flaviviruses
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批准号:DP240102506
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项目类别:Discovery Projects
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资助金额:$44.16万
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财政年份:2024
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负责人:Prof Alexander Khromykh
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依托单位:
Noncoding RNAs of insect-specific flaviviruses: biogenesis and functions
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批准号:DP190103304
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项目类别:Discovery Projects
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资助金额:$30.5万
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财政年份:2019
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负责人:Prof Alexander Khromykh
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依托单位:
The role of noncoding viral RNAs in flavivirus infection and exosomal signalling
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批准号:nhmrc : GNT1127916
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项目类别:Project Grants
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资助金额:$68.34万
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财政年份:2017
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负责人:Prof Alexander Khromykh
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依托单位:
The role of noncoding viral RNAs in flavivirus infection and exosomal signalling
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批准号:nhmrc : 1127916
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项目类别:Project Grants
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资助金额:$46.64万
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财政年份:2017
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负责人:Prof Alexander Khromykh
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依托单位:
Host genes controlling Flavivirus infection: new insights and application for developing highly effective Kunjin replicon-based Ebola vaccine
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批准号:nhmrc : GNT1102421
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项目类别:Project Grants
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资助金额:$73.7万
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财政年份:2016
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负责人:Prof Alexander Khromykh
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依托单位:
Host genes controlling Flavivirus infection: new insights and application for developing highly effective Kunjin replicon-based Ebola vaccine
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批准号:nhmrc : 1102421
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项目类别:Project Grants
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资助金额:$50.62万
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财政年份:2016
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负责人:Prof Alexander Khromykh
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依托单位:
Pathogenic flaviviruses: molecular mechanisms of disease, host response and vaccines
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批准号:nhmrc : 1059794
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项目类别:Research Fellowships
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资助金额:$46.49万
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财政年份:2014
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负责人:Prof Alexander Khromykh
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依托单位:
Wolbachia and West Nile virus in mosquitoes: friends or foes?
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批准号:nhmrc : 1062983
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项目类别:Project Grants
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资助金额:$37.41万
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财政年份:2014
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负责人:Prof Alexander Khromykh
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依托单位:
The role of noncoding subgenomic flavivirus RNA in virus-host interactions
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批准号:nhmrc : 1045080
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项目类别:Project Grants
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资助金额:$41.64万
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财政年份:2013
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负责人:Prof Alexander Khromykh
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依托单位:
Role of flavivirus-encoded small regulatory RNAs in virus-mosquito vector interactions
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批准号:nhmrc : 1027110
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项目类别:Project Grants
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资助金额:$36.49万
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财政年份:2012
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负责人:Prof Alexander Khromykh
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依托单位:
A functional interaction between domains of the flavivirus NS5 protein presents a new target for antiviral therapy
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批准号:nhmrc : 631520
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项目类别:NHMRC Project Grants
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资助金额:$33.53万
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财政年份:2010
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负责人:Prof Alexander Khromykh
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依托单位:
Uncoupled Research Fellowship
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批准号:nhmrc : 569537
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项目类别:NHMRC Research Fellowships
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资助金额:$38.72万
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财政年份:2009
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负责人:Prof Alexander Khromykh
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依托单位:
Virulence determinants of encephalitic flaviviruses
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批准号:nhmrc : 456126
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项目类别:NHMRC Project Grants
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资助金额:$30.38万
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财政年份:2008
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负责人:Prof Alexander Khromykh
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依托单位:
The West Nile viral protease, NS3: a target for antiviral drug and vaccine design
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批准号:nhmrc : 351594
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项目类别:NHMRC Project Grants
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资助金额:$15.37万
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财政年份:2005
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负责人:Prof Alexander Khromykh
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依托单位:
Kunjin replicons for gene therapy and protein manufacture
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批准号:nhmrc : 241967
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项目类别:NHMRC Development Grants
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资助金额:$20.67万
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财政年份:2003
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负责人:Prof Alexander Khromykh
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依托单位:
Molecular analyses of flavivirus RNA replication, encapsidation, and complementation
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批准号:nhmrc : 142983
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项目类别:NHMRC Project Grants
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资助金额:$40.18万
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财政年份:2001
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负责人:Prof Alexander Khromykh
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依托单位:
Kunjin virus replicon-based vaccine vectors: new developments and applications
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批准号:nhmrc : 142911
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项目类别:NHMRC Project Grants
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资助金额:$15.14万
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财政年份:2001
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负责人:Prof Alexander Khromykh
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依托单位:
Molecular mechanisms of flavivirus rna replication
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批准号:nhmrc : 981442
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项目类别:NHMRC Project Grants
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资助金额:$33.37万
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财政年份:1998
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负责人:Prof Alexander Khromykh
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依托单位:
海外基金