Role of flavivirus-encoded small regulatory RNAs in virus-mosquito vector interactions

黄病毒编码的小调节RNA在病毒-蚊子载体相互作用中的作用

• 批准号: nhmrc : 1027110
• 负责人: Prof Alexander Khromykh
• 金额: $ 36.49万
• 依托单位: The University of Queensland
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2012
• 资助国家: 澳大利亚
• 起止时间: 2012-01-01 至 2014-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/role-flavivirus-encoded-vector-interactions/110540
• 关键词: Role; flavivirus; encoded; small; regulatory

Mosquito-borne diseases are major threats to human health. MicroRNAs are small non-coding ribonucleic acids (RNAs) that play important roles in development, cancer, apoptosis, immunity, longevity, and viral infections. We propose to identify the regulatory microRNAs from flaviviruses and establish their potential function in vector-arboviruses interactions. The project will put Australia at the forefront of research in the most rapidly developing area of microRNA research.

蚊媒疾病是人类健康的主要威胁。MicroRNA是一种小的非编码核糖核酸（RNA），在发育、癌症、细胞凋亡、免疫、长寿和病毒感染中发挥重要作用。我们建议从黄病毒中鉴定出调控microRNA，并确定它们在载体-虫媒病毒相互作用中的潜在功能。该项目将使澳大利亚在microRNA研究发展最快的领域处于研究的前沿。