Boston University Clinical and Translational Science Institute
波士顿大学临床与转化科学研究所
基本信息
- 批准号:9126634
- 负责人:
- 金额:$ 56.84万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2015
- 资助国家:美国
- 起止时间:2015-08-13 至 2019-03-31
- 项目状态:已结题
- 来源:
- 关键词:AddressAdoptedAffinityAreaBasic ScienceBiologicalBiomedical EngineeringBiomedical ResearchBone RegenerationBostonCardiologyClinicalClinical SciencesCollaborationsDentistryDermatologyDevelopmentDisciplineDoctor of PhilosophyDrug Delivery SystemsEducational CurriculumEffectivenessEnvironmentFacultyFinancial SupportFloorFosteringFoundationsFramingham Heart StudyFundingFutureGastroenterologyGeriatricsGoalsHematologyHome environmentHousingIndustryInstitutesInstitutionIntentionInterdisciplinary StudyInternationalLaboratoriesLeadershipLearningMarketingMedicalMedicineMentorsMissionMolecular MedicineOrthopedicsOutcomePatientsPediatric OncologyPediatric Surgical ProceduresPerformancePeripheralPharmaceutical PreparationsPhenotypePlayPositioning AttributePostdoctoral FellowProcessProductivityProgram EvaluationPublicationsPulmonologyRegenerative MedicineResearchResearch PersonnelResearch TrainingResourcesRoleScienceScientistSecureShapesSickle CellStem Cell ResearchStem cellsStudentsStudy SubjectTNFSF15 geneTeaching MethodTechnologyTimeToxicity TestsTrainingTraining ProgramsTranslational ResearchUniversitiesVisionVocational GuidanceWorkforce Developmentbasebench to bedsidecareercareer developmentcell bankdesigneducation researchefficacy testingexperiencefoothuman diseaseinnovationinterdisciplinary approachinterestmedical schoolsmembermid-career facultymultidisciplinarypersonalized medicinephysical sciencepre-doctoralprogramsskillssuccessteachertooltranslational medicine
项目摘要
The overarching concepts and goals of the Regenerative Medicine Training Program (RMTP
TL1) are to 1) provide an innovative, integrative and interdisciplinary training program for pre-
doctoral and post-doctoral trainees which will leverage a unique and internationally recognized
strength of BU, 2) establish an environment that facilitates translational team science
interactions with trainees, MD scientists and clinicians, thereby synergistically bridging research
strengths with interdisciplinary approaches in regenerative medicine, and 3) catapult BU into the
forefront of institutions that are producing scientists with the skills and expertise to fulfill a
current and future patient-based need for regenerative medicine. The objectives of our training
program also align precisely with the general Boston University CTSI (BU CTSI) goals and with
the strong emphasis on regenerative medicine at Boston University School of Medicine, as well
as to further the mission of NCATS of expediting personalized medicine and the discovery and
delivery of drugs to market. The RMTP will provide support for 3 pre-doctoral and 2 post-
doctoral trainees each year, totaling 27 pre-doctoral and 18 post-doctoral trainees supported for
the duration of the program, with each trainee participating for two years. Accepted trainees will
be outstanding students/postdocs and selected based on grades/productivity, quality of the
proposal, likely to pursue careers in academic regenerative medicine, highly motivated,
energetic, and well-prepared for the curriculum. The curriculum will be competency-based and
include rigorous training in didactic and laboratory based concepts and technology. An
extensive and individualized mentoring plan will be implemented for each trainee that will
included both scientific as well career development guidance. We fully anticipate that under the
vision of “todays trainees are the teachers of tomorrow”, the RMTP will generate a continual
influx of research and clinical leaders in the stem cell/regenerative medicine field who will make
significant contributions resulting in the realization of its full medical potential. We seek to retain
a major portion of our trainees, both in our own program and elsewhere, as investigators and
mentors in regenerative medicine. Success of the RMTP will be based on the ability to increase
the pipeline of well-trained scientists who continue their research in regenerative medicine, the
number and quality of their publications, and leadership positions they assume in both industry
and academic environments.
再生医学培训计划(RMTP)的总体概念和目标
TL 1)是1)提供一个创新的,综合性的和跨学科的培训计划,
博士和博士后学员,这将利用独特的和国际公认的
BU的优势,2)建立促进转化团队科学的环境
与学员,医学博士科学家和临床医生的互动,从而协同桥接研究
优势与再生医学的跨学科方法,和3)弹射BU进入
这些机构正在培养具有技能和专业知识的科学家,以实现
当前和未来的患者对再生医学的需求。我们的培训目标
该计划还与波士顿大学CTSI(BU CTSI)的总体目标和
波士顿大学医学院对再生医学的高度重视,
为了推进NCATS加快个性化医疗和发现的使命,
将药品推向市场。RMTP将为3名博士前和2名博士后提供支持。
博士研究生每年,共27名博士前和18名博士后研究生支持,
该计划的持续时间,每个受训者参加两年。接受培训的学员将
是优秀的学生/博士后,并根据成绩/生产力,质量的选择
建议,可能追求学术再生医学的职业生涯,积极性高,
精力充沛,为课程做好充分准备。课程将以能力为基础,
包括教学和实验室概念和技术的严格培训。一个
将为每个受训者实施广泛和个性化的指导计划,
包括科学和职业发展指导。我们完全预计,
“今天的学员是明天的教师”的愿景,RMTP将产生持续的
在干细胞/再生医学领域的研究和临床领导者的涌入,谁将使
为充分发挥其医疗潜力做出了重大贡献。我们力求保留
我们的大部分学员,无论是在我们自己的计划和其他地方,作为调查员,
再生医学的导师RMTP的成功将取决于提高
训练有素的科学家继续他们在再生医学方面的研究,
出版物的数量和质量,以及他们在这两个行业中所担任的领导地位
学术环境。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Darrell N. Kotton其他文献
Patient-Specific Inducible Pluripotent Stem Cells Reveal Mechanism of Personalized Therapy for an Inherited Cardiac Arrhythmia
- DOI:
10.1016/j.bpj.2011.11.2947 - 发表时间:
2012-01-31 - 期刊:
- 影响因子:
- 作者:
Kai Wang;Cecile Terrenoire;Kevin J. Sampson;Vivek Lyer;Kelvin W. Chan Tung;Jonathan Lu;Wendy Chung;Robert H. Pass;Gordon Keller;Darrell N. Kotton;Robert S. Kass - 通讯作者:
Robert S. Kass
Derivation of transplantable human thyroid follicular epithelial cells from induced pluripotent stem cells
- DOI:
10.1016/j.stemcr.2024.10.004 - 发表时间:
2024-12-10 - 期刊:
- 影响因子:
- 作者:
Hendrik J. Undeutsch;Alberto Posabella;Andrea B. Alber;Pushpinder S. Bawa;Carlos Villacorta-Martin;Feiya Wang;Laertis Ikonomou;Darrell N. Kotton;Anthony N. Hollenberg - 通讯作者:
Anthony N. Hollenberg
The COPD GWAS gene emADGRG6/em instructs function and injury response in human iPSC-derived type II alveolar epithelial cells
慢性阻塞性肺疾病全基因组关联研究基因 emADGRG6/em 指导人诱导多能干细胞来源的 II 型肺泡上皮细胞的功能和损伤反应
- DOI:
10.1016/j.ajhg.2023.08.017 - 发表时间:
2023-10-05 - 期刊:
- 影响因子:8.100
- 作者:
Rhiannon B. Werder;Kayleigh A. Berthiaume;Carly Merritt;Marissa Gallagher;Carlos Villacorta-Martin;Feiya Wang;Pushpinder Bawa;Vidhi Malik;Shawn M. Lyons;Maria C. Basil;Edward E. Morrisey;Darrell N. Kotton;Xiaobo Zhou;Michael H. Cho;Andrew A. Wilson - 通讯作者:
Andrew A. Wilson
Nascent matrix deposition supports alveolar organoid formation from aggregates in synthetic hydrogels
新生基质沉积有助于在合成水凝胶中由聚集体形成肺泡类器官
- DOI:
10.1016/j.stemcr.2024.11.006 - 发表时间:
2025-01-14 - 期刊:
- 影响因子:5.100
- 作者:
Madeline K. Eiken;Charlie J. Childs;Lindy K. Brastrom;Tristan Frum;Eleanor M. Plaster;Donia W. Ahmed;Ryan C. Spencer;Orren Shachaf;Suzanne Pfeiffer;Justin E. Levine;Konstantinos-Dionysios Alysandratos;Darrell N. Kotton;Jason R. Spence;Claudia Loebel - 通讯作者:
Claudia Loebel
Lung stem cells
- DOI:
10.1007/s00441-007-0479-2 - 发表时间:
2007-09-06 - 期刊:
- 影响因子:2.900
- 作者:
Darrell N. Kotton;Alan Fine - 通讯作者:
Alan Fine
Darrell N. Kotton的其他文献
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{{ truncateString('Darrell N. Kotton', 18)}}的其他基金
Developing a patient-specific organoid model of pulmonary fibrosis using iPSCs
使用 iPSC 开发患者特异性肺纤维化类器官模型
- 批准号:
10026360 - 财政年份:2020
- 资助金额:
$ 56.84万 - 项目类别:
Developing a patient-specific organoid model of pulmonary fibrosis using iPSCs
使用 iPSC 开发患者特异性肺纤维化类器官模型
- 批准号:
10318560 - 财政年份:2020
- 资助金额:
$ 56.84万 - 项目类别:
Developing a patient-specific organoid model of pulmonary fibrosis using iPSCs
使用 iPSC 开发患者特异性肺纤维化类器官模型
- 批准号:
10525231 - 财政年份:2020
- 资助金额:
$ 56.84万 - 项目类别:
Editing Alveolar Progenitor Cells for Correction of Monogenic Disease
编辑肺泡祖细胞以纠正单基因疾病
- 批准号:
10198995 - 财政年份:2016
- 资助金额:
$ 56.84万 - 项目类别:
Editing Alveolar Progenitor Cells for Correction of Monogenic Disease
编辑肺泡祖细胞以纠正单基因疾病
- 批准号:
10417109 - 财政年份:2016
- 资助金额:
$ 56.84万 - 项目类别:
Epigenenomic and transcriptomic networks in normal and defective lung development
正常和有缺陷的肺发育中的表观基因组和转录组网络
- 批准号:
9144829 - 财政年份:2015
- 资助金额:
$ 56.84万 - 项目类别:
Epigenenomic and transcriptomic networks in normal and defective lung development
正常和有缺陷的肺发育中的表观基因组和转录组网络
- 批准号:
8927909 - 财政年份:2015
- 资助金额:
$ 56.84万 - 项目类别:
Boston University Clinical and Translational Science Institute
波士顿大学临床与转化科学研究所
- 批准号:
9261614 - 财政年份:2015
- 资助金额:
$ 56.84万 - 项目类别:
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