Neurologic Clinical Epidemiology Training Grant

描述(由申请人提供)：宾夕法尼亚大学佩雷尔曼医学院(PSOM)临床流行病学和生物统计学中心(CCEB)和神经病学系，包括儿童神经病学部，建议继续并加强为临床医生提供的创新、严格和成功的两到三年神经临床流行病学研究培训计划。这个培训项目吸引了很多人 学员来自全国的院校；它的毕业生被安置在全国的院校，从而产生了一个影响很大的项目。培训计划包括流行病学、临床研究方法学、生物统计学和神经学临床流行病学的必修课；与受训者的方法学兴趣相关的选修课；由CCEB和神经病学系的参与教师举办的期刊俱乐部和临床研究会议；广泛的独立阅读材料；负责任的研究指导；专业发展系列；补助金撰写和发展经验；与经验丰富的研究员的学徒经历；以及完成神经病学临床研究的独立研究项目。该计划：1)培训临床医生成为严格和独立的学术调查人员，能够使用流行病学中的一系列方法来解决神经系统疾病的研究问题，这些疾病与病因、预后、预防和早期发现、治疗、临床经济学、技术评估、医疗决策和患者护理质量有关；2)在临床流行病学和神经病学的教师指导下提供密切指导的研究经验；以及3)加强传统流行病学和神经病学之间的联系。学员攻读临床流行病学理学硕士(MSCE)课程。拟议计划的优势是：1)CCEB和神经病学系成功研究和培训计划的悠久历史，包括这一培训计划；2)对神经疾病临床研究感兴趣的教职员工之间建立的合作联系；3)为学员提供的全面课程和研究计划；以及4)具有成功培训记录的广泛经验和多学科的教职员工。此外，许多现有的大型数据库可用于研究项目和培训，广泛的专业分析能力可用于采用方法的临床研究 临床流行病学(例如，临床试验、病例对照、队列研究等)以及教职员工对合作研究和培训的承诺，共同为此提供了一个理想的环境 培训计划。最后，宾夕法尼亚大学和PSOM促进了一种学术环境，在这种环境中，基础和临床研究受到鼓励，并被视为对医生有吸引力的职业道路。

DESCRIPTION (provided by applicant): The Center for Clinical Epidemiology and Biostatistics (CCEB) and the Department of Neurology, including the Division of Child Neurology, all of the Perelman School of Medicine (PSOM) at the University of Pennsylvania (Penn), propose to continue and enhance an innovative, rigorous, and successful two- to three- year research training program for clinicians in neurologic clinical epidemiology. This training program attracts trainees from institutions nationwide; its graduates are placed in institutions nationwide, resulting in a program of high impact. The training program consists of required courses in epidemiology, clinical research methodology, biostatistics, and neurologic clinical epidemiology; elective courses relevant to the trainees' methodological interests; journal clubs and clinical research conferences conducted by participating faculty in the CCEB and the Department of Neurology; extensive independent readings; instruction in the responsible conduct of research; a professional development series; grant writing and grant development experiences; an apprenticeship experience with an experienced investigator; and the completion of an independent research project in neurologic clinical research. The program: 1) trains clinicians to be rigorous and independent academic investigators able to use the range of approaches available in epidemiology to address research issues in neurologic diseases related to the etiology, prognosis, prevention and early detection, treatment, clinical economics, technology assessment, medical decision making, and quality of patient care; 2) provides closely mentored research experiences with faculty preceptors in clinical epidemiology and neurology; and 3) strengthen the links between traditional epidemiology and neurology. Trainees matriculate in the Master of Science in Clinical Epidemiology (MSCE) program. Strengths of the proposed program are: 1) the long history of successful research and training programs in the CCEB and the Department of Neurology, including this training program; 2) the collaborative links that have been forged among faculty with interests in clinical research in neurologic diseases; 3) the comprehensive course offerings and research programs that are available to trainees; and 4) an extensive set of experienced and multidisciplinary faculty with successful training records. In addition, numerous existing large databases that can be used for research projects and training, a broad array of specialized analytic capabilities available for clinical studies employing methods of clinical epidemiology (e.g., clinical trials, case-control, cohort research, etc.), and commitmet of faculty to collaborative research and training, combine to provide an ideal environment for this training program. Finally, Penn and the PSOM promote an academic environment in which basic and clinical research are encouraged and viewed as attractive career paths for physicians.