Neurologic Clinical Epidemiology Training Program

临床流行病学和生物统计学中心（CCEB）和神经病学系 宾夕法尼亚大学（Penn）医学院（SOM）与 费城儿童医院神经科儿科建议开发一种创新的 博士后神经病学临床流行病学培训计划。宾夕法尼亚大学和SOM促进了一个学术 鼓励基础和临床研究的环境，并将其视为有吸引力的职业道路， 实习生该机构还吸引了来自全国其他机构的学员，从而促进了 想法和指导风格。 该计划是专门设计来训练临床医生已经在神经病学培训是严格的， 独立的学术研究人员能够使用流行病学中可用的一系列方法， 解决有关病因，预后，预防和早期发现，治疗， 临床经济学、技术评估、医疗决策和患者护理质量 神经系统疾病具体来说，学员将应用临床流行病学的方法，以广泛的 神经病学内的子专业范围，包括神经眼科学，多发性硬化症，神经， 肿瘤学、癫痫、认知神经学、中风和运动障碍。 为期两到三年的培训计划包括临床流行病学，研究 方法学、生物统计学和神经病学临床流行病学;期刊俱乐部和临床研究 专注于神经病学研究问题的会议;广泛的独立阅读;出席和 参加CCEB、神经科和神经科的研究研讨会 （儿科）;并完成一个独立的研究项目。具体而言，该方案旨在： (1)提供适合临床研究的研究技术的深入知识;（2）提供 在临床流行病学和神经病学研究方面与导师的研究经验;以及（3）汇集 教师和研究员在CCEB，神经病学系，神经病学（儿科）的部门。 受训者在临床流行病学（MSCE）学位课程的科学硕士录取，这是 由CCEB管理。 拟议计划的优势是：1）在美国成功的研究培训计划的悠久历史， CCEB; 2）为学员提供的全面课程和研究计划; 3） CCEB、神经病学系和神经病学系之间存在的合作联系， 神经病学（儿科）; 4）和一个广泛的经验丰富的项目主任和教师导师， 成功的培训记录。此外，学院在以下方面拥有广泛的丰富专业知识： CCEB，神经科和神经科（儿科）;许多现有的大型 可用于研究项目和培训的数据库;广泛的专业分析 可用于临床研究的能力（即，临床试验，病例对照，队列研究）;以及学院的 致力于合作研究和培训，为这一培训计划提供了理想的环境。

The Center for Clinical Epidemiology and Biostatistics (CCEB) and the Department of Neurology of the University of Pennsylvania (Penn) School of Medicine (SOM), in collaboration with the Department of Pediatrics, Division of Neurology, of Children's Hospital of Philadelphia propose to develop an innovative post-doctoral neurologic clinical epidemiology training program. Penn and the SOM promote an academic environment in which basic and clinical research are encouraged and viewed as attractive career paths for trainees. The institution also attracts trainees from other institutions nationwide, thus promoting exchange of ideas and mentoring styles. This program is specifically designed to train clinicians already trained in neurology to be rigorous, independent academic investigators able to use the range of approaches available in epidemiology to address clinical research issues regarding the etiology, prognosis, prevention and early detection, treatment, clinical economics, technology assessment, medical decision making, and quality of patient care of neurologic diseases. Specifically, trainees will apply the methods of clinical epidemiology to a broad spectrum of sub-specialties within Neurology, including neuro-ophthalmology, multiple sclerosis, neuro- oncology, epilepsy, cognitive neurology, stroke, and movement disorders. The two- to three-year training program consists of required courses in clinical epidemiology, research methodology, biostatistics, and neurologic clinical epidemiology; journal clubs and clinical research conferences focusing on research issues in neurology; extensive independent readings; attendance at and participation in research seminars at the CCEB, Department of Neurology, and Division of Neurology (Pediatrics); and the completion of an independent research project. Specifically, the program is designed to: (1) provide in-depth knowledge of the research techniques appropriate to clinical research; (2) provide research experience with mentors in clinical epidemiology and neurology research; and (3) bring together faculty and fellows in the CCEB, the Department of Neurology, and the Division of Neurology (Pediatrics). Trainees matriculate in the Master of Science in Clinical Epidemiology (MSCE) degree program, which is managed by the CCEB. Strengths of the proposed program are: 1) the long history of successful research training programs in the CCEB; 2) the comprehensive course offerings and research programs that are available to trainees; 3) the collaborative links that exist among the CCEB, the Department of Neurology, and the Division of Neurology (Pediatrics); 4) and an extensive set of experienced program directors and faculty preceptors with successful training records. In addition, the availability of the broad range of rich expertise of the faculties in the CCEB, Department of Neurology, and Division of Neurology (Pediatrics); numerous existing large databases available that can be used for research projects and training; a broad array of specialized analytic capabilities available for clinical studies (i.e., clinical trials, case-control, cohort research); and the faculties' commitment to collaborative research and training, provide an ideal environment for this training program.