Training Interdisciplinary Pharmacology Scientists

培养跨学科药理学科学家

基本信息

项目摘要

PROJECT SUMMARY / ABSTRACT Training Interdisciplinary Pharmacology Scientists (TIPS) will train predoctoral students to address critical issues in drug development, by providing them the tools and knowledge to navigate the ever- changing, interdisciplinary landscape that makes up today’s basic, translational, and clinical research. This T32 program is designed to create leaders in the broadly defined field of Pharmacological Sciences. TIPS will provide interdisciplinary training in drug development including screening, computation, medicinal chemistry, and structural biology relevant to target discovery and validation, while exploring how to maximize therapeutic benefit, minimize toxicity and implement precision medicine. Through the participation of 3 premier and neighboring biomedical research institutions and their graduate schools (University of Texas Health Science Center at Houston, Baylor College of Medicine, and Rice University), TIPS will provide interdisciplinary training, career development activities and industry shadowships that will prepare students to advance biomedical research through successful careers in academia, government and regulatory agencies, and industry. Program leadership includes the program director and co-director and a steering committee of representatives from the participating graduate schools, with assistance from an advisory committee of diverse experts. TIPS program requirements and benefits will include co-mentoring from two faculty in a collaborative research project; specific didactic and elective courses (available to TIPS trainees at all participating graduate schools); monthly trainee meetings to build a unified cohort; career development activities, and required training in the responsible conduct of research. Mentors will include 26 faculty members at 3 institutions, working in 9 different departments and two interdepartmental graduate programs, who have training and research expertise in drug/compound screening, pharmacology, computation, medicinal chemistry, structural biology, systems biology, biochemistry, genetics, and molecular and cellular biology. All participating departments recruit nationwide, especially for under-represented minority students and students with disabilities. This provides a large, diverse pool of predoctoral students from a variety of backgrounds for our 5 requested slots. Students will apply to TIPS after joining a lab near the end of their first year or during their second year of graduate school, and if selected through a competitive application process, will receive two years of support. Reappointment to a second year will be contingent on a thorough oral and written review of trainee research progress and completion of program requirements. TIPS will complement the degree requirements of a trainee’s home institution, causing no delay in degree completion. The interdisciplinary skills emphasized by this program will produce pharmacology scientists well positioned to advance biomedical research and to address the complexity of drug development.
项目摘要/摘要

项目成果

期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)

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Carmen W. Dessauer其他文献

Spatial organization of adenylyl cyclase and its impact on dopamine signaling in neurons
腺苷酸环化酶的空间组织及其对神经元中多巴胺信号传导的影响
  • DOI:
    10.1038/s41467-024-52575-0
  • 发表时间:
    2024-09-27
  • 期刊:
  • 影响因子:
    15.700
  • 作者:
    Léa Ripoll;Yong Li;Carmen W. Dessauer;Mark von Zastrow
  • 通讯作者:
    Mark von Zastrow
Gβγ Activates GIRK2 with Low-Micromolar Affinity with Distinct Activation Pattern Compared to GIRK1/2
  • DOI:
    10.1016/j.bpj.2019.11.1557
  • 发表时间:
    2020-02-07
  • 期刊:
  • 影响因子:
  • 作者:
    Daniel Yakubovich;Uri Kahanovitch;Galit Tabak;Tal Keren Raifman;Vladimir Tsemakhovich;Debi Ranjan Tripathy;Carmen W. Dessauer;Joel A. Hirsch;Nathan Dascal
  • 通讯作者:
    Nathan Dascal
Preferential Association with Gβγ Over Gα Governs the Activity of a G Protein-Activated K+ Channel
  • DOI:
    10.1016/j.bpj.2011.11.2939
  • 发表时间:
    2012-01-31
  • 期刊:
  • 影响因子:
  • 作者:
    Daniel Yakubovich;Shai Berlin;Moran Rubinstein;Uri Kahanovich;Carmen W. Dessauer;Nathan Dascal
  • 通讯作者:
    Nathan Dascal
Deficient Regulation of Gbetagamma Effectors by Fluorescently Labeled Galpha i3 Subunits Reveals Distinct Aspects of Coupling to GIRK and Cav2.2 Channels
  • DOI:
    10.1016/j.bpj.2010.12.1624
  • 发表时间:
    2011-02-02
  • 期刊:
  • 影响因子:
  • 作者:
    Shai Berlin;Vladimir Tsemakhovich;Carmen W. Dessauer;Nathan Dascal
  • 通讯作者:
    Nathan Dascal

Carmen W. Dessauer的其他文献

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{{ truncateString('Carmen W. Dessauer', 18)}}的其他基金

Regulation of Adenylyl Cyclase Signaling Pathways
腺苷酸环化酶信号通路的调节
  • 批准号:
    10689698
  • 财政年份:
    2022
  • 资助金额:
    $ 20.48万
  • 项目类别:
Regulation of Adenylyl Cyclase Signaling Pathways
腺苷酸环化酶信号通路的调节
  • 批准号:
    10405311
  • 财政年份:
    2022
  • 资助金额:
    $ 20.48万
  • 项目类别:
Training Interdisciplinary Pharmacology Scientists (TIPS)
培训跨学科药理学科学家(TIPS)
  • 批准号:
    10398794
  • 财政年份:
    2021
  • 资助金额:
    $ 20.48万
  • 项目类别:
Training Interdisciplinary Pharmacology Scientists (TIPS)
培训跨学科药理学科学家(TIPS)
  • 批准号:
    10615102
  • 财政年份:
    2021
  • 资助金额:
    $ 20.48万
  • 项目类别:
Training Interdisciplinary Pharmacology Scientists (TIPS)
培训跨学科药理学科学家(TIPS)
  • 批准号:
    10088894
  • 财政年份:
    2021
  • 资助金额:
    $ 20.48万
  • 项目类别:
Mechanisms of cAMP signaling that drive spontaneous activity in nociceptors
驱动伤害感受器自发活动的 cAMP 信号传导机制
  • 批准号:
    9751983
  • 财政年份:
    2015
  • 资助金额:
    $ 20.48万
  • 项目类别:
Mechanisms of cAMP signaling that drive spontaneous activity in nociceptors
驱动伤害感受器自发活动的 cAMP 信号传导机制
  • 批准号:
    10266146
  • 财政年份:
    2015
  • 资助金额:
    $ 20.48万
  • 项目类别:
Mechanisms of cAMP signaling that drive spontaneous activity in nociceptors
驱动伤害感受器自发活动的 cAMP 信号传导机制
  • 批准号:
    9538268
  • 财政年份:
    2015
  • 资助金额:
    $ 20.48万
  • 项目类别:
Mechanisms of cAMP signaling that drive spontaneous activity in nociceptors
驱动伤害感受器自发活动的 cAMP 信号传导机制
  • 批准号:
    10670321
  • 财政年份:
    2015
  • 资助金额:
    $ 20.48万
  • 项目类别:
Mechanisms of cAMP signaling that drive spontaneous activity in nociceptors
驱动伤害感受器自发活动的 cAMP 信号传导机制
  • 批准号:
    9318602
  • 财政年份:
    2015
  • 资助金额:
    $ 20.48万
  • 项目类别:

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