Mechanisms of nonsuicidal self-injury facilitating transitions to suicidal behavior

非自杀性自残促进向自杀行为转变的机制

• 批准号: 9171067
• 负责人: Jennifer Jo Muehlenkamp
• 金额: $ 40.22万
• 依托单位: UNIVERSITY OF WISCONSIN EAU CLAIRE
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-08-01 至 2020-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9171067
• 关键词: Address; Age; Anxiety; Behavior; Behavioral; Burn injury; Cause of Death; Centers for Disease Control and Prevention (U.S.); Cessation of life; Characteristics; Common Data Element; Counseling; Data; Death Rate; Development; Effectiveness; Ensure; Feeling hopeless; Feeling suicidal; Frequencies; Future; Goals; Growth; Individual; Intervention; Interview; Knowledge; Laboratories; Lead; Longitudinal Studies; Measures; Mediating; Mediator of activation protein; Mental Depression; Modeling; Monitor; Office for Human Research Protections; Pain; Patient Self-Report; Pattern; Procedures; Protocols documentation; Public Health; Reaction Time; Recording of previous events; Recruitment Activity; Reporting; Research; Risk; Risk Factors; Safety; Self-Injurious Behavior; Services; Severities; Skin; Students; Suicide; Suicide attempt; Suicide prevention; Surveys; Thinking; Time; Tissues; Translating; Universities; Youth; affection; age group; attentional bias; clinical practice; college; coping; design; habituation; injured; male; non-suicidal self injury; primary outcome; programs; prospective; psychologic; psychosocial; retention rate; screening; suicidal; suicidal behavior; suicidal morbidity; suicidal risk; theories; university student; young adult

Project Summary Deaths from suicide continue to be a major public health concern, particularly among youth and young adults, for whom suicide ranks as the second leading cause of death. Despite growing research on suicide, knowledge about the proximal behavioral and psychosocial mechanisms that facilitate the development of suicidal thinking and/or the transition to suicidal behavior. Nonsuicidal self-injury (NSSI) is the intentional destruction of body tissue without suicidal intent, typically cutting or burning the skin, and has been identified as a particularly robust risk factor for suicide. Studies find that up to 19% of college students report engaging in NSSI during their college years, placing many at elevated risk for suicide. Remarkably little is known about the temporal course of NSSI and suicide ideation/ behavior, or about why and how NSSI confers its risk for suicide. The proposed study aims to fill these knowledge gaps through an 18-month longitudinal study of self-injuring college students. Using the integrative motivational- volitional theory of suicide as a guide, the current study proposes that the behavioral severity of NSSI, lack of effectiveness of the NSSI in achieving coping functions, and self-identification with NSSI are mechanisms contributing to the development of suicidal ideation. Whereas, habituation to pain and fearlessness about death, attentional bias towards self-injury, and impulsively engaging in NSSI are mechanisms mediating the transition from NSSI to suicide behavior. College students reporting current NSSI will be recruited to complete behavioral-reaction time tasks and self-report measures of the study variables within a laboratory setting at baseline, 6-, 12-, and 18-months post baseline. Latent growth modeling will be used to examine how the proposed NSSI mechanisms mediate changes in suicidal ideation and attempts over time. The results will provide essential information to the field of suicide prevention, and have the potential to significantly impact clinical practice by identifying specific mechanisms and markers of suicide risk that can be translated into assessment and intervention strategies.

项目概要 自杀死亡仍然是一个主要的公共卫生问题，特别是在青少年中， 对于他们来说，自杀是第二大死因。尽管对自杀的研究不断增多，但知识 关于促进自杀想法发展的近端行为和心理社会机制 和/或向自杀行为的转变。非自杀性自伤（NSSI）是故意破坏身体 没有自杀意图的组织，通常切割或烧伤皮肤，并已被确定为特别 自杀的强大危险因素。研究发现，高达 19% 的大学生表示在学习期间参与了 NSSI 大学时期，使许多人面临较高的自杀风险。人们对时间的认识知之甚少 NSSI 和自杀意念/行为的过程，或 NSSI 为何以及如何带来自杀风险。这 拟议的研究旨在通过为期 18 个月的自伤纵向研究来填补这些知识空白 大学生。本研究以自杀综合动机-意志理论为指导 提出 NSSI 的行为严重性、NSSI 在实现应对功能方面缺乏有效性、 和 NSSI 的自我认同是导致自杀意念发展的机制。 然而，对痛苦的习惯和对死亡的无畏、对自残的注意力偏见，以及 冲动地参与 NSSI 是介导从 NSSI 到自杀行为转变的机制。大学 将招募报告当前 NSSI 的学生来完成行为反应时间任务和自我报告 在实验室环境中测量基线、基线后 6、12 和 18 个月的研究变量。 潜在增长模型将用于检查所提出的 NSSI 机制如何调节 随着时间的推移出现自杀意念和尝试。研究结果将为自杀领域提供重要信息 预防，并有可能通过确定具体机制对临床实践产生重大影响 以及可以转化为评估和干预策略的自杀风险标记。