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Priming, Recruitment and Retention of influenza virus specific CD8 T cells in the upper airways

Priming, Recruitment and Retention of influenza virus specific CD8 T cells in the upper airways
上呼吸道中流感病毒特异性 CD8 T 细胞的启动、招募和保留
批准号:
nhmrc : 1143735
负责人:
Dr Linda Wakim
金额:
$42.82万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2018
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2018-01-01 至 2020-12-31

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中文摘要
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英文摘要
Influenza virus gains entry into the body by inhalation and initiates its replication cycle within the upper airways. This early stage of infection, when the amount of influenza virus is low, provides the ideal window of opportunity for an effective immune response to limit disease progression. In this proposal we will define the immunity that can be evoked within the upper airways and determine immune mechanisms left behind that can safeguard this region from this important respiratory pathogen
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Priming, Recruitment and Retention of influenza virus specific CD8 T cells in the upper airways
  • 批准号:
    nhmrc : GNT1143735
  • 项目类别:
    Project Grants
  • 资助金额:
    $63.34万
  • 财政年份:
    2018
  • 负责人:
    Dr Linda Wakim
  • 依托单位:
Identifying the mechanism and spectrum of activity of the antiviral protein IFITM3
  • 批准号:
    nhmrc : 1059051
  • 项目类别:
    Project Grants
  • 资助金额:
    $33.82万
  • 财政年份:
    2014
  • 负责人:
    Dr Linda Wakim
  • 依托单位:
IFITM3 - making cells resistant to virus infection
  • 批准号:
    nhmrc : GNT1059051
  • 项目类别:
    Project Grants
  • 资助金额:
    $32.71万
  • 财政年份:
    2014
  • 负责人:
    Dr Linda Wakim
  • 依托单位:
Long lived, virus resistant resident memory T cells
  • 批准号:
    nhmrc : 1045205
  • 项目类别:
    Career Development Fellowships
  • 资助金额:
    $27.69万
  • 财政年份:
    2013
  • 负责人:
    Dr Linda Wakim
  • 依托单位:
海外基金