Priming, Recruitment and Retention of influenza virus specific CD8 T cells in the upper airways
上呼吸道中流感病毒特异性 CD8 T 细胞的启动、招募和保留
基本信息
- 批准号:nhmrc : 1143735
- 负责人:
- 金额:$ 42.82万
- 依托单位:
- 依托单位国家:澳大利亚
- 项目类别:Project Grants
- 财政年份:2018
- 资助国家:澳大利亚
- 起止时间:2018-01-01 至 2020-12-31
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
Influenza virus gains entry into the body by inhalation and initiates its replication cycle within the upper airways. This early stage of infection, when the amount of influenza virus is low, provides the ideal window of opportunity for an effective immune response to limit disease progression. In this proposal we will define the immunity that can be evoked within the upper airways and determine immune mechanisms left behind that can safeguard this region from this important respiratory pathogen
流感病毒通过吸入进入人体,并在上呼吸道内启动其复制周期。这种感染的早期阶段,当流感病毒的量很低时,为有效的免疫反应提供了理想的机会窗口,以限制疾病的进展。在这个建议中,我们将定义上呼吸道内可以诱发的免疫,并确定可以保护该区域免受这种重要呼吸道病原体侵害的免疫机制
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Dr Linda Wakim其他文献
Dr Linda Wakim的其他文献
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{{ truncateString('Dr Linda Wakim', 18)}}的其他基金
Priming, Recruitment and Retention of influenza virus specific CD8 T cells in the upper airways
上呼吸道中流感病毒特异性 CD8 T 细胞的启动、招募和保留
- 批准号:
nhmrc : GNT1143735 - 财政年份:2018
- 资助金额:
$ 42.82万 - 项目类别:
Project Grants
Identifying the mechanism and spectrum of activity of the antiviral protein IFITM3
鉴定抗病毒蛋白 IFITM3 的机制和活性谱
- 批准号:
nhmrc : 1059051 - 财政年份:2014
- 资助金额:
$ 42.82万 - 项目类别:
Project Grants
IFITM3 - making cells resistant to virus infection
IFITM3 - 使细胞抵抗病毒感染
- 批准号:
nhmrc : GNT1059051 - 财政年份:2014
- 资助金额:
$ 42.82万 - 项目类别:
Project Grants
Long lived, virus resistant resident memory T cells
长寿、抗病毒的常驻记忆 T 细胞
- 批准号:
nhmrc : 1045205 - 财政年份:2013
- 资助金额:
$ 42.82万 - 项目类别:
Career Development Fellowships
Virus resistant mucosal resident memory T cells
抗病毒粘膜常驻记忆T细胞
- 批准号:
nhmrc : 1042530 - 财政年份:2013
- 资助金额:
$ 42.82万 - 项目类别:
Project Grants
An exploration of the balance between West Nile Virus pathogenesis and immune system mediated control
西尼罗河病毒发病机制与免疫系统介导控制之间平衡的探索
- 批准号:
nhmrc : 567011 - 财政年份:2009
- 资助金额:
$ 42.82万 - 项目类别:
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