An exploration of the balance between West Nile Virus pathogenesis and immune system mediated control

西尼罗河病毒（WNV）是一种蚊子传播的传染病，正在全球范围内出现。感染可导致致命性脑炎的发展，目前还没有可供人类使用的疫苗。杀伤性T细胞是免疫系统的一个组成部分，对于从大脑中清除病毒至关重要。该项目旨在进一步探索西尼罗河病毒的发病机制，以及是否可以利用杀伤性T细胞来保持感染局部化并防止病毒传播到大脑。

West Nile Virus (WNV) is a mosquito transmitted infectious disease that is emerging globally. Infection can lead to the development of fatal encephalitis and currently there is no vaccine available for human use. Killer T cells, a component of the immune system, are essential for viral clearance from the brain. This project aims to further explore WNV pathogenesis and whether killer T cells can be utilized to keep the infection localised and prevent the spread of the virus to the brain.