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An RNA Element Negatively Regulates Initation HIV-1 Reverse transcription and Inhibits Proviral Integration

An RNA Element Negatively Regulates Initation HIV-1 Reverse transcription and Inhibits Proviral Integration
RNA 元件负调控 HIV-1 逆转录起始并抑制原病毒整合
批准号:
nhmrc : 1004715
负责人:
A/Pr David Harrich
金额:
$38.78万
依托单位国家:
澳大利亚
项目类别:
NHMRC Project Grants
财政年份:
2011
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2011-01-01 至 2013-12-31

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中文摘要
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英文摘要
We recently made the discovery that the virus that causes AIDS can be potently inhibited by stimulating a specific step in the virus life cycle. Our evidence suggests this stimulation is controlled by a host factor which will be identified in this study. Its discovery would be an important step towards a new means to fight HIV infection.
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A potent anti-HIV-1 gene therapy agent in a humanised mouse model
A potent anti-HIV-1 gene therapy agent in a humanised mouse model
  • 批准号:
    nhmrc : GNT1085359
  • 项目类别:
    Project Grants
  • 资助金额:
    $110.11万
  • 财政年份:
    2015
  • 负责人:
    A/Pr David Harrich
  • 依托单位:
eEF1A1 is critical for HIV-1 reverse transcription and replication
The Human Eukaryotic Translation Elongation Factor 1A is a Paramyxovirus Virus Dependency Factor
国内基金
海外基金
毛竹MLE(mariner-like element)转座酶催化机理研究
  • 批准号:
    LZ19C160001
  • 项目类别:
    省市级项目
  • 资助金额:
    --
  • 批准年份:
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  • 负责人:
    周明兵
  • 依托单位: