The CDP ethanolamine pathway: a new player in obesity induced insulin resistance

CDP乙醇胺途径：肥胖诱导的胰岛素抵抗的新参与者

• 批准号: nhmrc : 1004239
• 负责人: A/Pr Clinton Bruce
• 金额: $ 43.5万
• 依托单位: Deakin University
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2011
• 资助国家: 澳大利亚
• 起止时间: 2011-01-01 至 2014-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/cdp-ethanolamine-pathway-insulin-resistance/109020
• 关键词: CDP; ethanolamine; pathway; new; player

Insulin resistance, a characteristic of type 2 diabetes, is linked to abnormal metabolism of lipid (fat) in tissues such as liver and muscle. This project aims to identify a novel pathway which may promote a build up of lipids in muscle and therefore leads to the development of type 2 diabetes. This work may provide a basis for understanding and optimizing treatment of insulin resistance by regulating the control of fat metabolism in muscle.

胰岛素抵抗是2型糖尿病的特征，与肝脏和肌肉等组织中脂质（脂肪）的异常代谢有关。该项目旨在确定一种新的途径，该途径可能促进肌肉中脂质的积累，从而导致2型糖尿病的发展。这项工作可能提供了一个基础，了解和优化治疗胰岛素抵抗通过调节控制脂肪代谢的肌肉。