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The effect of metals on neurofibrillary tangle formation

The effect of metals on neurofibrillary tangle formation
金属对神经原纤维缠结形成的影响
批准号:
nhmrc : 509276
负责人:
A/Pr Paul Adlard
金额:
$22.23万
依托单位:
依托单位国家:
澳大利亚
项目类别:
NHMRC Project Grants
财政年份:
2008
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2008-01-01 至 2010-12-31

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中文摘要
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英文摘要
The majority of studies into Alzheimer's disease (AD) have focussed on two brain lesions- the plaque and neurofibrillary tangle (NFT), which are believed to have a causative role in AD. Our lab has made several seminal discoveries about the role that metals play in the development of plaques. We are now extending this work to evaluate the role of metals in NFT formation. These studies will provide insight into the formation and possible treatments for this primary brain lesion in AD.
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会议论文
Metal-mediated mechanisms and therapeutic approaches for treating brain injury across age
  • 批准号:
    nhmrc : GNT1141597
  • 项目类别:
    Project Grants
  • 资助金额:
    $122.98万
  • 财政年份:
    2018
  • 负责人:
    A/Pr Paul Adlard
  • 依托单位:
Metal-mediated mechanisms and therapeutic approaches for treating brain injury across age
  • 批准号:
    nhmrc : 1141597
  • 项目类别:
    Project Grants
  • 资助金额:
    $83.15万
  • 财政年份:
    2018
  • 负责人:
    A/Pr Paul Adlard
  • 依托单位:
The role of beta-Amyloid Precursor Protein and Tau in the regulation of neuronal iron
  • 批准号:
    nhmrc : 1025774
  • 项目类别:
    Project Grants
  • 资助金额:
    $43.36万
  • 财政年份:
    2012
  • 负责人:
    A/Pr Paul Adlard
  • 依托单位:
The role of metals in healthy brain aging: identification of novel compounds to prevent age-related cognitive decline
  • 批准号:
    nhmrc : 1027379
  • 项目类别:
    Project Grants
  • 资助金额:
    $52.66万
  • 财政年份:
    2012
  • 负责人:
    A/Pr Paul Adlard
  • 依托单位:
国内基金
海外基金
Rare Metals(稀有金属(英文版))
红树对重金属的定位累积及耦合微观分析与耐受策略研究
  • 批准号:
    30970527
  • 项目类别:
    面上项目
  • 资助金额:
    35.0万元
  • 批准年份:
    2009
  • 负责人:
    严重玲
  • 依托单位: