High-power 1H/19F amplifier for the 500 MHz NMR spectrometer

固态核磁共振（NMR）已成为在分子水平上表征固体材料最有用和用途最广的技术之一，可用于研究晶体材料、玻璃和无序材料、金属合金、生物膜、蛋白质、药物、农产品、聚合物等。在分子水平上表征这种固体材料使研究人员能够深入了解新材料的合理设计及其体积特性的原子起源。这种理解已经并将继续产生巨大的科学、技术和经济影响。温莎大学化学与生物化学系有一个活跃的固态核磁共振研究小组（Schurko教授），参与研究固体材料，如催化茂金属、纳米颗粒、超分子层状材料和药物。目前，他的团队有一个全职的专用光谱仪（Varian），以及一个由部门共享的固态核磁共振兼职光谱仪（Bruker）。Schurko的小组与许多其他研究小组合作，并为他们提供服务。Loeb（超分子体系），Antonelli（介孔固体，燃料电池），Macdonald（有机金属，聚合物）和Eichhorn（液晶，纳米颗粒）。由于对固态核磁共振时间和协作的需求增加，必须将兼职光谱仪升级到全功能。布鲁克DRX-500配备了固态核磁共振；然而，在常规实验中至关重要的质子放大器功率太低，无法用于常规的固态核磁共振实验。我们建议交易我们的旧放大器（100w），并升级到一个新的300w放大器，用于1H和19F NMR应用。这将允许在现场进行广泛的常规和专业固态核磁共振实验，使该部门的所有研究小组受益。

Solid-state nuclear magnetic resonance (NMR) has become one of the most useful and versatile techniques for characterizing solid materials at the molecular level, and can be applied to study crystalline materials, glasses and disordered materials,  metal alloys, biomembranes, proteins, drugs, agricultural products, polymers, etc.  Characterizing such solid materials at the molecular level gives researchers insight into the rational design of new materials and the atomic origins of their bulk properties.   Such understanding has and will continue to have enormous scientific, technological and economic impact.    The Department of Chemistry and Biochemistry at the University of Windsor has an active solid-state NMR research group (Prof. Schurko) that is involved in studying the solid materials such as catalytic metallocenes, nanoparticles, supramolecular layered materials and pharmaceuticals.  There is currently a full-time dedicated spectrometer (Varian) for his group, and a part-time spectrometer (Bruker) for solid-state NMR which is shared by the department.  Schurko's group collaborates and performs service work for a number of other research groups, including Profs. Loeb (supramolecular systems), Antonelli (mesoporous solids, fuel cells), Macdonald (organometallics, polymers) and Eichhorn (liquid crystals, nanoparticles).  Due to the increased demand for solid-state NMR time and collaboration, the part-time spectrometer must be upgraded to full capability.    The Bruker DRX-500 is equipped for solid-state NMR; however, the proton amplifier, which is crucial in many routine experiments, is too low power to be of use in routine solid-state NMR experiments.  We are proposing to trade in our old amplifier (100 W) and upgrade to a new 300 W amplifier for 1H and 19F NMR applications.  This will permit a wide range of routine and specialized solid-state NMR experiments to be conducted on site, benefitting all of the research groups in the department.