High-power 1H/19F amplifier for the 500 MHz NMR spectrometer

适用于 500 MHz NMR 波谱仪的高功率 1H/19F 放大器

• 批准号: 345519-2007
• 负责人: Schurko, Robert
• 金额: $ 4.59万
• 依托单位: University of Windsor
• 依托单位国家: 加拿大
• 项目类别: Research Tools and Instruments - Category 1 (<$150,000)
• 财政年份: 2006
• 资助国家: 加拿大
• 起止时间: 2006-01-01 至 2007-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=325966
• 关键词: power; 1H; 19F; amplifier; 500

Solid-state nuclear magnetic resonance (NMR) has become one of the most useful and versatile techniques for characterizing solid materials at the molecular level, and can be applied to study crystalline materials, glasses and disordered materials,  metal alloys, biomembranes, proteins, drugs, agricultural products, polymers, etc.  Characterizing such solid materials at the molecular level gives researchers insight into the rational design of new materials and the atomic origins of their bulk properties.   Such understanding has and will continue to have enormous scientific, technological and economic impact.    The Department of Chemistry and Biochemistry at the University of Windsor has an active solid-state NMR research group (Prof. Schurko) that is involved in studying the solid materials such as catalytic metallocenes, nanoparticles, supramolecular layered materials and pharmaceuticals.  There is currently a full-time dedicated spectrometer (Varian) for his group, and a part-time spectrometer (Bruker) for solid-state NMR which is shared by the department.  Schurko's group collaborates and performs service work for a number of other research groups, including Profs. Loeb (supramolecular systems), Antonelli (mesoporous solids, fuel cells), Macdonald (organometallics, polymers) and Eichhorn (liquid crystals, nanoparticles).  Due to the increased demand for solid-state NMR time and collaboration, the part-time spectrometer must be upgraded to full capability.    The Bruker DRX-500 is equipped for solid-state NMR; however, the proton amplifier, which is crucial in many routine experiments, is too low power to be of use in routine solid-state NMR experiments.  We are proposing to trade in our old amplifier (100 W) and upgrade to a new 300 W amplifier for 1H and 19F NMR applications.  This will permit a wide range of routine and specialized solid-state NMR experiments to be conducted on site, benefitting all of the research groups in the department.

固态核磁共振（NMR）已经成为在分子水平上表征固体材料的最有用和最通用的技术之一，并且可以应用于研究晶体材料、玻璃和无序材料、金属合金、生物膜、蛋白质、药物、农产品、聚合物、在分子水平上表征这种固体材料使研究人员深入了解新材料的合理设计及其整体性质的原子起源。 这种认识已经并将继续产生巨大的科学、技术和经济影响。 温莎大学的化学和生物化学系有一个活跃的固态核磁共振研究小组（Prof. Schurko），该研究所从事催化烯烃、纳米颗粒、超分子层状材料和药物等固体材料的研究。目前，他所在的研究组有一台全职专用光谱仪（Varian），Schurko的研究小组与其他一些研究小组合作，并为他们提供服务，其中包括：Loeb（超分子系统）、Antonelli（介孔固体、燃料电池）、Macdonald（有机金属、聚合物）和Eichhorn（液晶、纳米颗粒）。由于对固态NMR时间和协作的需求增加，兼职光谱仪必须升级到全功能。 Bruker DRX-500配备固态NMR;然而，在许多常规实验中至关重要的质子放大器，功率太低，不能用于常规的固体核磁共振实验。我们建议以旧的放大器（100 W）进行交易。并升级到一个新的300 W放大器，用于1H和19F NMR应用。这将允许在现场进行广泛的常规和专业固态NMR实验，使系里的所有研究小组都受益。