Biomechanical, Neural and Sensory Phenotyping of the Upper Airway in Obstructive Sleep Apnoea

阻塞性睡眠呼吸暂停上呼吸道的生物力学、神经和感觉表型

• 批准号: nhmrc : 1058974
• 负责人: A/Pr David Mckenzie
• 金额: $ 49.75万
• 依托单位: The University of New South Wales
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2014
• 资助国家: 澳大利亚
• 起止时间: 2014-01-01 至 2017-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/biomechanical-neural-sensory-sleep-apnoea/454718
• 关键词: Biomechanical; Neural; Sensory; Phenotyping; Upper

Obstructive sleep apnoea (OSA) is a common disorder where the upper airway closes repeatedly during sleep. It results in daytime sleepiness, increased risk of accidents and cardiovascular disease. But not all patients are the same, and individually tailored treatments are needed. This project will develop new ways to identify the causes of OSA in individual patients, using new MRI imaging methods, sensory testing, and measurements of the neural activity in the muscles that keep the airway open.

阻塞性睡眠呼吸暂停 (OSA) 是一种常见疾病，患者在睡眠期间上呼吸道反复关闭。它会导致白天嗜睡，增加发生事故和心血管疾病的风险。但并非所有患者都是一样的，需要个体化治疗。该项目将开发新方法，使用新的 MRI 成像方法、感官测试和保持气道开放的肌肉神经活动测量来确定个体患者 OSA 的病因。