Control of human inspiratory muscles in health and disease

健康和疾病中人体呼吸肌的控制

• 批准号: nhmrc : 568701
• 负责人: A/Pr David Mckenzie
• 金额: $ 26.45万
• 依托单位: The University of New South Wales
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2009
• 资助国家: 澳大利亚
• 起止时间: 2009-01-01 至 2011-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/control-human-inspiratory-health-disease/81618
• 关键词: Control; human; inspiratory; muscles; health

This project will study how human inspiratory muscles that 'pump' air into the lungs and upper airway 'dilator' muscles are controlled in normal healthy subjects and subjects with respiratory disorders such as obstructive sleep apnoea. We will study (i) the output to the inspiratory muscles, (ii) the interation of automatic and voluntary control of breathing, and (iii) reflex connections of human pump and dilator muscles. This work promises new understanding of basic and patho-physiology.

该项目将研究正常健康受试者和患有阻塞性睡眠呼吸暂停等呼吸系统疾病的受试者如何控制将空气“泵入”肺部的人类吸气肌和上呼吸道“扩张器”肌肉。我们将研究（i）吸气肌的输出，（ii）自动和自愿呼吸控制的相互作用，以及（iii）人体泵和扩张肌的反射连接。这项工作带来了对基础和病理生理学的新理解。