Inert atmosphere glovebox for synthetic inorganic, organometallic chemistry at ryerson

瑞尔森用于合成无机、有机金属化学的惰性气氛手套箱

• 批准号: 360121-2008
• 负责人: Foucher, Daniel
• 金额: $ 4.92万
• 依托单位: Ryerson University
• 依托单位国家: 加拿大
• 项目类别: Research Tools and Instruments - Category 1 (<$150,000)
• 财政年份: 2007
• 资助国家: 加拿大
• 起止时间: 2007-01-01 至 2008-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=365408
• 关键词: Inert; atmosphere; glovebox; synthetic; inorganic

The proposed equipment is an inert atmosphere double glovebox required for a variety of applications in the synthetic inorganic, organic and polymer chemistries carried out at Ryerson University.  The inert atmosphere of the glovebox allows for the preparation, storage and safe handling of small to moderate quantities of moisture and air sensitive compounds. Moisture and air levels are maintained at < 1 ppm by the continuous recirculation of the inert atmosphere (Nitrogen or Argon) over drying columns. Storage and transfer of pyrophoric or moisture sensitive materials is facilitated by ready access through small and large port doors.  Reactions, weighing operations, sample preparation, and crystal growth of sensitive materials are safely and readily carried out in the glovebox. The low temperature refrigerator (-35 oC) provides an additional advantage of storing heat sensitive reactive materials in the glove box, or as a suitable location to recrystallize recovered air and moisture sensitive materials. Proper use of the glovebox can lead to higher synthetic yields, longer shelf life and storage of sensitive materials, and safer working conditions. The higher productivity and greater degree of safety expected with the glovebox would be realized by the participants on this RTI.  Daniel Foucher will use this glovebox to prepare air and moisture sensitive tin compounds in the preparation of polymers for applications in inkjet printable circuitry. Rob Gossage will use the glovebox to prepare and recrystalize air and moisture sensitive transition metal complexes with applications as catalysts and breast cancer therapies. Russell Viirre will use this equipment in the development of new reactions for the synthesis of medicinal compounds and molecular sensors.

拟议的设备是在瑞尔森大学进行的合成无机、有机和聚合物化学中的各种应用所需的惰性气氛双手套箱。手套箱的惰性气氛允许制备、储存和安全处理小到中等数量的湿气和空气敏感化合物。通过干燥柱上惰性气氛(氮气或氩气)的持续循环，水分和空气水平保持在1ppm。通过小的和大的港口门可以方便地储存和转移发火或湿气敏感材料。敏感材料的化学反应、称重操作、样品制备和晶体生长都可以在手套箱中安全、方便地进行。低温冰箱(-35oC)提供了一个额外的优势，可以将热敏反应材料储存在手套箱中，或作为回收的空气和湿敏材料重结晶的合适位置。正确使用手套盒可以带来更高的合成产率、更长的保质期和敏感材料的储存，以及更安全的工作条件。本次RTI的参与者将实现手套盒所期望的更高的生产率和更大的安全程度。丹尼尔·福彻将使用这种手套盒来制备空气和湿气敏感的锡化合物，以制备用于喷墨打印电路应用的聚合物。Rob Gossage将使用这种手套盒来制备和重结晶对空气和湿度敏感的过渡金属络合物，并将其应用于催化剂和乳腺癌治疗。Russell Viirre将使用该设备开发合成药物化合物和分子传感器的新反应。