In situ visualisation of cell fate commitment in haematopoiesis, immune cells and tissue remodelling.

造血、免疫细胞和组织重塑中细胞命运承诺的原位可视化。

• 批准号: nhmrc : GNT1159488
• 负责人: A/Pr Edwin Hawkins
• 金额: $ 48.34万
• 依托单位国家: 澳大利亚
• 项目类别: Career Development Fellowships
• 财政年份: 2019
• 资助国家: 澳大利亚
• 起止时间: 2019-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/situ-visualisation-cell-tissue-remodelling/1349295
• 关键词: situ; visualisation; cell; fate; commitment

White blood cells are the key components of the immune system that protect us from infection. Their growth is tightly regulated, and when they malfunction, they can expand rapidy to cause blood cancers and or autoimmune diseases. The aim of this work is to use cutting edge technology to observe these disease causing cells in their natural environment so we can better understand their strengths and weaknesses. This information will help us design new treatments for these devastating diseases.

白血球是保护我们免受感染的免疫系统的关键组成部分。它们的生长受到严格的控制，当它们出现故障时，它们会迅速扩张，导致血癌和/或自身免疫性疾病。这项工作的目的是利用尖端技术在自然环境中观察这些致病细胞，以便我们更好地了解它们的优势和劣势。这些信息将帮助我们设计针对这些毁灭性疾病的新疗法。