Snail family proteins regulate stem cell differentiation

蜗牛家族蛋白调节干细胞分化

• 批准号: nhmrc : 520307
• 负责人: Dr Gregory Somers
• 金额: $ 19.25万
• 依托单位: La Trobe University
• 依托单位国家: 澳大利亚
• 项目类别: Early Career Fellowships
• 财政年份: 2008
• 资助国家: 澳大利亚
• 起止时间: 2008-01-01 至 2012-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/snail-family-proteins-cell-differentiation/115778
• 关键词: Snail; family; proteins; regulate; stem

This research aims to discover the role of a family of genes in regulating stem cells. These genes are known to turn other genes off and we have shown that this family is required to maintain stem cells in animal tissues. The current research seeks to determine which genes are normally switched off in order to maintain normal stem cells. We also aim to determine if turning these genes on leads to cancer formation.

本研究旨在发现一个基因家族在调节干细胞中的作用。众所周知，这些基因可以关闭其他基因，我们已经证明，这个家族是维持动物组织中的干细胞所必需的。目前的研究试图确定哪些基因通常被关闭以维持正常的干细胞。我们还旨在确定开启这些基因是否会导致癌症的形成。