Studies of the genetics of spotting in domestic dogs

家犬斑点的遗传学研究

• 批准号: 360663-2007
• 负责人: Schmutz, Sheila
• 金额: $ 0.95万
• 依托单位: University of Saskatchewan
• 依托单位国家: 加拿大
• 项目类别: Collaborative Research and Development Grants
• 财政年份: 2008
• 资助国家: 加拿大
• 起止时间: 2008-01-01 至 2009-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=403829
• 关键词: Studies; genetics; spotting; domestic; dogs

This study will focus on developing DNA tests for dogs that are spotted or ticked. In many breeds there are several forms of spotting and not all are equally desirable by individual breeders or by the breed as a whole. In other breeds there are solid or spotted dogs of only a single pattern of spotting, such as Newfoundlands. Developing DNA testing for these breeds will need to take such information into account. The gene MITF has recently been shown to be associated with some forms of spotting in dogs and so this needs to be studied more fully. Ticking is a pattern or small pigmented areas within larger nonpigmented areas. Hence ticking only shows on dogs with white markings. We will study several candidate genes to determine if they might be associated with ticking.

这项研究的重点是为有斑点或有斑点的狗开发DNA测试。在许多品种中，有几种形式的斑点，并不是所有的斑点都同样适合单个育种者或整个品种。在其他品种中，只有一种斑点图案的纯色或斑点狗，如纽芬兰。为这些品种开发DNA测试将需要考虑到这些信息。基因MITF最近被证明与狗的某些斑点有关，所以这需要更充分的研究。滴答是在较大的非色素区域内的小色素区域的图案。因此嘀嗒声只出现在白色斑纹的狗身上。我们将研究几个候选基因，以确定它们是否可能与滴答声有关。