STRUCTURE, FUNCTION AND REGULATION OF F-TYPE ATP SYNTHASES

F 型 ATP 合酶的结构、功能和调控

• 批准号: nhmrc : 1047004
• 负责人: Dr Daniela Stock
• 金额: $ 36.32万
• 依托单位: Victor Chang Cardiac Research Institute
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2013
• 资助国家: 澳大利亚
• 起止时间: 2013-01-01 至 2016-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/structure-function-regulation-atp-synthases/111896
• 关键词: STRUCTURE; FUNCTION; REGULATION; TYPE; ATP

ATP synthase is the molecular machinery that converts energy derived from nutrients or photosynthesis into the universal biological energy carrier ATP (adenosine triphosphate). This is one of the most fundamental processes of life and is conserved from bacteria to plants to humans. Understanding how bacterial and mitochondrial ATP synthases work in molecular detail will have wide-ranging implications for both medicine (in understanding metabolic disorders, controlled cell death and aging) and the design of new antibacterial agents.

三磷酸腺苷合成酶是一种分子机制，它将来自营养或光合作用的能量转化为普遍存在的生物能量载体三磷酸腺苷。这是最基本的生命过程之一，从细菌到植物再到人类都是保守的。了解细菌和线粒体ATP合成酶在分子细节上是如何工作的，将对医学(在理解新陈代谢障碍、受控的细胞死亡和衰老)和设计新的抗菌剂方面具有广泛的意义。