Structure, function and dynamics of ATP synthases and rotary proton pumps

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ATP synthase is the molecular machinery that converts energy derived from nutrients or photosynthesis into the universal biological fuel source ATP (adenosine triphosphate). This is one of the most fundamental processes of life and is conserved from bacteria to plants to humans. Understanding how ATP synthase and its relatives work in molecular detail is expected to have wide-ranging implications for both medicine (in understanding metabolic disorders) and the design of new antibacterial agents.