Structural studies of membrane protein complexes

膜蛋白复合物的结构研究

• 批准号: nhmrc : 1109961
• 负责人: Dr Daniela Stock
• 金额: $ 42.1万
• 依托单位: Victor Chang Cardiac Research Institute
• 依托单位国家: 澳大利亚
• 项目类别: Research Fellowships
• 财政年份: 2016
• 资助国家: 澳大利亚
• 起止时间: 2016-01-01 至 2020-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/structural-studies-membrane-protein-complexes/663105
• 关键词: Structural; studies; membrane; protein; complexes

Life needs energy. We breathe and eat to make the universal biological fuel adenosine triphosphate (ATP). We turn over our own body weight in ATP every day and imbalances in this process lead to severe disorders such as obesity, diabetes and heart disease as well as to ageing. For any real breakthroughs we need to understand the machinery behind biological energy conversion in molecular detail and this is what my laboratory is aiming to achieve.

生命需要能量。我们呼吸和进食是为了制造通用的生物燃料三磷酸腺苷(ATP)。我们每天将自己的体重转化为三磷酸腺苷，这个过程中的失衡会导致严重的疾病，如肥胖、糖尿病、心脏病以及衰老。对于任何真正的突破，我们需要详细了解生物能量转化背后的分子机制，这也是我的实验室致力于实现的目标。